GCSAM

Gene Symbol GCSAM
Entrez Gene 257144
Alt Symbol GCAT2, GCET2, HGAL
Species Human
Gene Type protein-coding
Description germinal center-associated, signaling and motility
Other Description germinal center B-cell-expressed transcript 2 protein|germinal center expressed transcript 2|germinal center-associated lymphoma protein|germinal center-associated signaling and motility protein|human germinal center-associated lymphoma
Swissprots C9JD17 Q8N6F7 C9JUG6
Accessions EAW79680 Q8N6F7 AA237025 AF521911 AAO21701 AK313368 BAG36167 AW576133 AY212246 AAO22147 BC030506 AAH30506 BM456595 BP224611 BX280641 DA455714 HQ447219 ADQ31706 XM_005247272 XP_005247329 XM_011512627 XP_011510929 XM_011512628 XP_011510930 XM_011512629 XP_011510931 XM_011512630 XP_011510932 NM_001190259 NP_001177188 NM_001190260 NP_001177189 NM_152785 NP_689998 NM_001008756
Function Involved in the negative regulation of lymphocyte motility. It mediates the migration-inhibitory effects of IL6. Serves as a positive regulator of the RhoA signaling pathway. Enhancement of RhoA activation results in inhibition of lymphocyte and lymphoma cell motility by activation of its downstream effector ROCK. Is a regulator of B-cell receptor signaling, that acts through SYK kinase activation. {ECO:0000269|PubMed:17823310, ECO:0000269|PubMed:20844236, ECO:0000269|PubMed:23299888}.
Subcellular Location Cytoplasm. Cell membrane. Note=It relocalizes from the cytoplasm to podosome-like structures upon cell treatment with IL6.
Tissue Specificity Expressed in diffuse large B-cell lymphoma (DLBCL) and several germinal center (GC)-like lymphoma cell lines (at protein level). Highly expressed in normal GC lymphocytes and GC-derived malignancies. Expressed in thymus and spleen. {ECO:0000269|PubMed:12509382, ECO:0000269|PubMed:12819018, ECO:0000269|PubMed:15677569}.

GCET2 (E-17) - sc-99903 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-GCET2 antibody - ab198731 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of Paraffin-embedded Human liver cancer tissue labeling GCET2 with ab198731 at 1/40 dilution.

Anti-GCET2 antibody - ab89180 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Anti-GCET2 antibody (ab89180) at 5 µg/ml + tagged, recombinant full length human GCET2 protein (the immunogen) at 0.2 µg

Anti-GCET2 antibody - ab69289 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-GCET2 antibody (ab69289) at 1/1000 dilutionLane 1 : GCET2 transfected 293T cell lysateLane 2 : Non-transfected lysateLysates/proteins at 25 µg per lane.

Anti-GCET2 antibody - ab86504 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-GCET2 antibody (ab86504) at 1 µg/ml (in 5% skim milk / PBS buffer) + 293T cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-GCET2 antibody [EPR14333] - ab185231 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Flow Cytometrical analysis of Raji cells labeling GCET2 with ab185231 at 1/230 and Goat anti rabbit IgG (FITC) at 1/150 as a secondary antibody compared to a negative control antibody.

Anti-GCET2 antibody [EPR14333-60] - ab185539 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR14333-60
Flow cytometry analysis of 2% paraformaldehyde fixed Jurkat cells labeling GCET2 with ab185539 at 1/130 dilution (pink) or a rabbit IgG isotype control (green), followed by secondary Goat anti rabbit IgG (FITC) at 1/150 dilution.

Anti-GCET2 / HGAL Antibody (clone MRQ-49) - LS-C202798 from LifeSpan Bioscience

Prices $560.00
Sizes 1 ml
Host Mouse
Clonality Monoclonal
Clone MRQ-49

Anti-GCET2 / HGAL Antibody - LS-C307656 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-GCET2 / HGAL Antibody (aa1-179) - LS-C129224 from LifeSpan Bioscience

Prices $445.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-GCET2 / HGAL Antibody (C-Terminus) - LS-C102662 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
GCET2 antibody LS-C102662 Western blot of Transfected 293T cell lysate.

GCET2 Antibody - NBP1-82693 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: GCET2 Antibody [NBP1-82693] - Lane 1: Marker [kDa] 220, 112, 84, 47, 32, 26, 17. Lane 2: Human cell line RT-4

GCET2 Antibody (1E9) - H00257144-M19 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1E9
Western Blot: GCET2 Antibody (1E9) [H00257144-M19] - Analysis of GCET2 expression in Jurkat (Cat # L017V1).

GCET2 Antibody - NBP1-54596 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal

GCET2 Antibody - H00257144-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

GCET2 Antibody - H00257144-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal

GCET2 Polyclonal Antibody - bs-6536R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Antigen: bs-6536P, 0.2ug/100ul \\nPrimary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000; \\nSecondary: HRP conjugated Goat Anti-Rabbit IgG(bs-0295G-HRP) at 1: 5000; \\nTMB staining; Read the data in Microplate Reader by 450nm\\n

Monoclonal Anti-GCET2 antibody produced in mouse - SAB1402072 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1E9
<B>Immunoblotting</B><BR/>Monoclonal Anti-GCET2, antibody produced in mouse, clone 1E9, purified immunoglobulin: <B>Cat. No. SAB1402072</B>: Antibody concentration: 1.0 - 5.0 μg/mL. Specific band of ~21.01 kDa using Jurkat lysate.

Anti-GCSAM antibody produced in rabbit - HPA002473 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-GCET2: <B>Cat. No. HPA002473</B>: Immunoperoxidase staining of formalin-fixed, paraffin-embedded human testis tissue showing positive staining of cells in ductus seminiferus.

Anti-GCET2 antibody produced in rabbit - SAB2103060 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-GCET2, antibody produced in rabbit: <B>Cat. No. SAB2103060</B>: Immunoblotting analysis of GCET2 in transfected 293T cell lysate with GCET2 anitbody at 1 μg/mL.

Anti-GCET2 antibody produced in mouse - SAB1408458 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-GCET2: <B>Cat. No. SAB1408458</B>: Antibody concentration: 0.1-5 μg/mL. Specific band of ~19.6 kDa using GCET2 transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

Anti-GCSAM antibody produced in rabbit - SAB4301203 from Sigma-Aldrich

Prices $230.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

GCET2 antibody - middle region (ARP55553_P050) - ARP55553_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

GCET2 antibody, Internal - GTX45254 from GeneTex

Prices $319.00
Sizes 50 μg
Host Rabbit
Clonality Polyclonal
Anti-GCET2 antibody, Internal used in Western blot. GTX45254

GCSAM Antibody (OABF01704) - OABF01704 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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