Gene Symbol | ASF1A |
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Entrez Gene | 25842 |
Alt Symbol | CGI-98, CIA, HSPC146 |
Species | Human |
Gene Type | protein-coding |
Description | anti-silencing function 1A histone chaperone |
Other Description | ASF1 anti-silencing function 1 homolog A|CCG1-interacting factor A|anti-silencing function protein 1 homolog A|hAsf1|hAsf1a|hCIA|histone chaperone ASF1A |
Swissprots | Q9P014 Q6IA08 Q9Y294 |
Accessions | EAW48193 Q9Y294 AA481056 AB028628 BAA96542 AF151856 AAD34093 AF161495 AAF29110 AF279306 AAK82972 AK025738 BAB15228 AL050261 CAB43363 BC010878 AAH10878 CR457347 CAG33628 DA902777 HQ447977 ADQ32460 NM_014034 NP_054753 |
Function | Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. Cooperates with chromatin assembly factor 1 (CAF-1) to promote replication-dependent chromatin assembly and with HIRA to promote replication-independent chromatin assembly. Required for the formation of senescence-associated heterochromatin foci (SAHF) and efficient senescence-associated cell cycle exit. {ECO:0000269|PubMed:10759893, ECO:0000269|PubMed:11897662, ECO:0000269|PubMed:12842904, ECO:0000269|PubMed:14718166, ECO:0000269|PubMed:15621527, ECO:0000269|PubMed:15664198, ECO:0000269|PubMed:16151251}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:11897662, ECO:0000269|PubMed:12842904}. |
Tissue Specificity | Ubiquitously expressed. {ECO:0000269|PubMed:12842904}. |
ASF1A (C6E10) Rabbit mAb - 2990 from Cell Signaling Technology
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ASF1A/B (4A1/3) - sc-53171 from Santa Cruz Biotechnology
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Anti-ASF1 A+B antibody [ASF 4A1/3] - ab31843 from Abcam
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Anti-ASF1A antibody - ab66754 from Abcam
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Anti-ASF1A antibody - ab197048 from Abcam
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Anti-ASF1a antibody - ab69935 from Abcam
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Anti-ASF1A Antibody (aa140-168, APC) - LS-C251857 from LifeSpan Bioscience
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Anti-ASF1A Antibody (aa121-170) - LS-C119336 from LifeSpan Bioscience
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Anti-ASF1A Antibody (N-Terminus) - LS-C117178 from LifeSpan Bioscience
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Anti-ASF1A Antibody (aa140-168, AP) - LS-C251856 from LifeSpan Bioscience
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Anti-ASF1A Antibody (aa140-168, FITC) - LS-C251859 from LifeSpan Bioscience
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Anti-ASF1A Antibody (aa140-168, Biotin) - LS-C251858 from LifeSpan Bioscience
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Anti-ASF1A Antibody (aa190-200) - LS-C54547 from LifeSpan Bioscience
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Anti-ASF1A Antibody (aa154-164) - LS-C54548 from LifeSpan Bioscience
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Anti-ASF1A Antibody (aa140-168, Azide-free, HRP) - LS-C251860 from LifeSpan Bioscience
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Anti-ASF1A Antibody (aa140-168) - LS-C159133 from LifeSpan Bioscience
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Anti-ASF1A Antibody (aa139-168) - LS-C319631 from LifeSpan Bioscience
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Anti-ASF1A Antibody (aa140-168, PE) - LS-C251861 from LifeSpan Bioscience
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Anti-ASF1A Antibody (aa114-205) - LS-C306404 from LifeSpan Bioscience
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Anti-ASF1A Antibody (C-Terminus) - LS-C345764 from LifeSpan Bioscience
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Anti-ASF1A Antibody - LS-C334765 from LifeSpan Bioscience
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Anti-ASF1A Antibody - LS-C334777 from LifeSpan Bioscience
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ASF1a Antibody - NB100-93376 from Novus Biologicals
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ASF1a Antibody - NBP1-55759 from Novus Biologicals
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ASF1a Antibody (2G10) - H00025842-M07A from Novus Biologicals
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