Gene Symbol | ASF1A |
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Entrez Gene | 25842 |
Alt Symbol | CGI-98, CIA, HSPC146 |
Species | Human |
Gene Type | protein-coding |
Description | anti-silencing function 1A histone chaperone |
Other Description | ASF1 anti-silencing function 1 homolog A|CCG1-interacting factor A|anti-silencing function protein 1 homolog A|hAsf1|hAsf1a|hCIA|histone chaperone ASF1A |
Swissprots | Q9P014 Q6IA08 Q9Y294 |
Accessions | EAW48193 Q9Y294 AA481056 AB028628 BAA96542 AF151856 AAD34093 AF161495 AAF29110 AF279306 AAK82972 AK025738 BAB15228 AL050261 CAB43363 BC010878 AAH10878 CR457347 CAG33628 DA902777 HQ447977 ADQ32460 NM_014034 NP_054753 |
Function | Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. Cooperates with chromatin assembly factor 1 (CAF-1) to promote replication-dependent chromatin assembly and with HIRA to promote replication-independent chromatin assembly. Required for the formation of senescence-associated heterochromatin foci (SAHF) and efficient senescence-associated cell cycle exit. {ECO:0000269|PubMed:10759893, ECO:0000269|PubMed:11897662, ECO:0000269|PubMed:12842904, ECO:0000269|PubMed:14718166, ECO:0000269|PubMed:15621527, ECO:0000269|PubMed:15664198, ECO:0000269|PubMed:16151251}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:11897662, ECO:0000269|PubMed:12842904}. |
Tissue Specificity | Ubiquitously expressed. {ECO:0000269|PubMed:12842904}. |
Human ASF1 A+B peptide - ab37490 from Abcam
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Human ASF1A full length protein - ab132261 from Abcam
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Human ASF1A full length protein - ab84211 from Abcam
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Human ASF1A full length protein - ab151335 from Abcam
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Human ASF1A full length protein - ab199600 from Abcam
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Human ASF1A peptide - ab71590 from Abcam
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ASF1A Antibody Blocking Peptide - LS-E4815 from LifeSpan Bioscience
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ASF1A Antibody Blocking Peptide - LS-E21315 from LifeSpan Bioscience
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ASF1A Antibody Blocking Peptide - LS-E26519 from LifeSpan Bioscience
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ASF1A Antibody Blocking Peptide - LS-E26345 from LifeSpan Bioscience
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ASF1a Recombinant Protein - H00025842-P01 from Novus Biologicals
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Recombinant Human ASF1a Protein - NBC1-22941 from Novus Biologicals
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ASF1A-Antibody-C-term-Blocking-Peptide - BP17195b from Abgent, a WuXi AppTec company
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ASF1A blocking peptide - GTX88909-PEP from GeneTex
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ASF1A blocking peptide - GTX88842-PEP from GeneTex
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ASF1A Protein (OPPA02069) - OPPA02069 from Aviva Systems Biology
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Human ASF1A protein - orb49439 from Biorbyt
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Human ASF1A protein - orb80932 from Biorbyt
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ASF1A Immunizing peptide - orb50351 from Biorbyt
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ASF1A Blocking Peptide - 33R-5680 from Fitzgerald
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ASF1A protein (His tag) - 80R-1135 from Fitzgerald
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ASF1A Peptide - AC21-1180-P from Abcore
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ASF1A Peptide - AC21-1355-P from Abcore
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ASF1A (1-204, His-tag) - AR09174PU-L from Acris Antibodies
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ASF1A (1-204, His-tag) - AR09174PU-N from Acris Antibodies
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