HHLA2

Gene Symbol	HHLA2
Entrez Gene	11148
Alt Symbol	B7H7
Species	Human
Gene Type	protein-coding
Description	HERV-H LTR-associating 2
Other Description	HERV-H LTR-associating protein 2|human endogenous retrovirus-H long terminal repeat-associating protein 2
Swissprots	Q9NWQ6 B4DKN2 Q9UM44 D3DN60
Accessions	EAW79727 EAW79728 Q9UM44 AF126162 AAD48396 AK000692 BAA91323 AK027132 AK097806 AK296644 BAG59244 AK315109 BC035971 AAH35971 BM980981 BP293912 DQ892610 ABM83536 DQ895850 ABM86776 XM_005247080 XP_005247137 XM_011512362 XP_011510664 XM_011512363 XP_011510665 XM_011512364 XP_011510666 XM_011512365 XP_011510667 XM_011512366 XP_011510668 XM_011512367 XP_011510669 XR_924094 XR_924095 NM_001282556 NP_001269485 NM_001282557 NP_001269486 NM_001282558 NP_001269487 NM_001282559 NP_001269488 NM_007072 NP_009003
Function	Through interaction with TMIGD2, costimulates T-cells in the context of TCR-mediated activation. Enhances T-cell proliferation and cytokine production via an AKT-dependent signaling cascade. {ECO:0000269|PubMed:23784006}.
Subcellular Location	Membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
Tissue Specificity	Expressed at high levels in colon, kidney, testis, lung and pancreas, and at lower levels in small intestine, liver and skeletal muscle. In immune cells, highly expressed in B- cells, dendritic cells and macrophages. Not detected in T-cells. {ECO:0000269|PubMed:10444326, ECO:0000269|PubMed:23784006}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human HHLA2 cDNA clone(NM_007072.2) - CDFH008457 from Creative Biomart Species Human Accession NM_007072.2

Human HHLA2 ORF Clone(NM_007072.2) - CDCL166010 from Creative Biomart Species Human Accession NM_007072.2

Human HHLA2 ORF Clone(NM_007072.2) - CDCR294342 from Creative Biomart Species Human Accession NM_007072.2

Human HHLA2 ORF Clone(NM_007072.2) - CDCR294343 from Creative Biomart Species Human Accession NM_007072.2

Human HHLA2 ORF Clone(NM_007072.2) - CDCR294344 from Creative Biomart Species Human Accession NM_007072.2

Human HHLA2 Gene cDNA Clone (full-length ORF Clone) - HG16139-G from Sino Biological Species Human Accession BC035971.1

Human HHLA2 natural ORF mammalian expression plasmid, N-His tag - HG16139-NH from Sino Biological Species Human Accession BC035971.1

Human HHLA2 Gene cDNA Clone (full-length ORF Clone), expression ready, C-HA-tagged - HG16139-CY from Sino Biological Species Human Accession BC035971.1

Human HHLA2 Gene cDNA Clone (full-length ORF Clone), expression ready, C-His-tagged - HG16139-CH from Sino Biological Species Human Accession BC035971.1

Human HHLA2 Gene cDNA Clone (full-length ORF Clone), expression ready, N-FLAG-tagged - HG16139-NF from Sino Biological Species Human Accession BC035971.1

Human HHLA2 Gene cDNA Clone (full-length ORF Clone), expression ready, N-Myc-tagged - HG16139-NM from Sino Biological Species Human Accession BC035971.1

Human HHLA2 natural ORF mammalian expression plasmid, N-HA tag - HG16139-NY from Sino Biological Species Human Accession BC035971.1

Human HHLA2 natural ORF mammalian expression plasmid, C-GFPSpark tag - HG16139-ACG from Sino Biological Species Human Accession BC035971.1

Human HHLA2 Gene cDNA Clone (full-length ORF Clone), expression ready, untagged - HG16139-UT from Sino Biological Species Human Accession BC035971.1

Human HHLA2 Gene cDNA Clone (full-length ORF Clone), expression ready, C-Myc-tagged - HG16139-CM from Sino Biological Species Human Accession BC035971.1

Human HHLA2 Gene cDNA Clone (full-length ORF Clone), expression ready, C-FLAG-tagged - HG16139-CF from Sino Biological Species Human Accession BC035971.1

Human B7-H7/HHLA2 (NP_009003) VersaClone cDNA - RDC1264 from R&D Systems Prices $199.00 Sizes 10 µg Species Human

Human HHLA2 ORF Clone(NM_007072.2) - CDCR294342 from Creative biogene Species Human

Human HHLA2 cDNA Clone(NM_007072.2) - CDFH008457 from Creative biogene Species Human

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