HHLA2

Gene Symbol	HHLA2
Entrez Gene	11148
Alt Symbol	B7H7
Species	Human
Gene Type	protein-coding
Description	HERV-H LTR-associating 2
Other Description	HERV-H LTR-associating protein 2|human endogenous retrovirus-H long terminal repeat-associating protein 2
Swissprots	Q9NWQ6 B4DKN2 Q9UM44 D3DN60
Accessions	EAW79727 EAW79728 Q9UM44 AF126162 AAD48396 AK000692 BAA91323 AK027132 AK097806 AK296644 BAG59244 AK315109 BC035971 AAH35971 BM980981 BP293912 DQ892610 ABM83536 DQ895850 ABM86776 XM_005247080 XP_005247137 XM_011512362 XP_011510664 XM_011512363 XP_011510665 XM_011512364 XP_011510666 XM_011512365 XP_011510667 XM_011512366 XP_011510668 XM_011512367 XP_011510669 XR_924094 XR_924095 NM_001282556 NP_001269485 NM_001282557 NP_001269486 NM_001282558 NP_001269487 NM_001282559 NP_001269488 NM_007072 NP_009003
Function	Through interaction with TMIGD2, costimulates T-cells in the context of TCR-mediated activation. Enhances T-cell proliferation and cytokine production via an AKT-dependent signaling cascade. {ECO:0000269|PubMed:23784006}.
Subcellular Location	Membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
Tissue Specificity	Expressed at high levels in colon, kidney, testis, lung and pancreas, and at lower levels in small intestine, liver and skeletal muscle. In immune cells, highly expressed in B- cells, dendritic cells and macrophages. Not detected in T-cells. {ECO:0000269|PubMed:10444326, ECO:0000269|PubMed:23784006}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human HHLA2 full length protein - ab161322 from Abcam Category Protein Source Wheat germ Species Human

HHLA2 Blocking Peptide - LS-E375 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human B7-H7/HHLA2 Protein - H00011148-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

HHLA2-Antibody-N-term-Blocking-Peptide - BP10650a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Recombinant Human B7-H7 Fc Chimera, CF - 8084-B7-050 from R&D Systems Category Protein Source Human embryonic kidney cell, HEK293-derived

Human B7H7 (Fc Tag) protein - orb232432 from Biorbyt Category Protein Prices $510.00, $1,088.00 Sizes 50 μg, 200 μg Species Human

HHLA2 - H00011148-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

HHLA2 - H00011148-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

HHLA2 fusion protein - Ag9822 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

HHLA2 fusion protein - ag9845 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human HHLA2, His-tagged - HHLA2-13768H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human HHLA2 - HHLA2-69H from Creative Biomart Category Protein Source HEK293 Cells Species Human

Recombinant Human HHLA2, Fc-tagged - HHLA2-548H from Creative Biomart Category Protein Source Human cells Species Human

Recombinant Human HHLA2, His-tagged - HHLA2-549H from Creative Biomart Category Protein Source Human cells Species Human

Recombinant Human HHLA2, Fc-tagged, Biotinylated - HHLA2-550H from Creative Biomart Category Protein Source Human cells Species Human

Human B7H7 / HHLA2 Protein (ECD, Fc Tag) - 16139-H02H-50 from Sino Biological Category Protein Source Human Cells Species Human

HHLA2 peptide - ab204539 from Abcam Category Peptide

Recombinant Human B7-H7/HHLA2 Fc Chimera Protein, CF - 8084-B7 from R&D Systems Category Protein Prices $339.00 Sizes 50 µg Source Human embryonic kidney cell, HEK293-derived Human B7-H7/HHLA2 (Ile23-Asn344) Accession # Q9UM44 IEGRMD Human IgG 1 (Pro100-Lys330) N-terminus C-terminus Species Human

B7-H7/HHLA2 Recombinant Protein Antigen - NBP2-49187PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E. coli Species Human

HHLA2 Peptide, Human - M34GP06978H from Creative Peptides Category Peptide Source Synthetic. Species Human

Human B7H7 / HHLA2 Protein (ECD, Fc Tag) - 16139-H02H from ABclonal Category Protein Prices $178.00, $448.00 Sizes 50 µg, 200 µg Source Human Cells Species Human

HERV-H LTR-associating protein 2 (HHLA2), Recombinant Protein - MBS7016602 from MyBioSource Category Protein Prices $1,200.00, $2,185.00, $3,390.00 Sizes 10 µg, 50 µg, 100 µg Source Cell Free Expression Species Human

Recombinant Human HHLA2 Protein, Fc-tagged - HHLA2-421H from Creative Biomart Category Protein Source HEK293 Species Human

Recombinant Human HHLA2 Protein, Fc-Avi-tagged, Biotinylated - HHLA2-551H from Creative Biomart Category Protein Source HEK293 Species Human

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