HHLA2

Gene Symbol HHLA2
Entrez Gene 11148
Alt Symbol B7H7
Species Human
Gene Type protein-coding
Description HERV-H LTR-associating 2
Other Description HERV-H LTR-associating protein 2|human endogenous retrovirus-H long terminal repeat-associating protein 2
Swissprots Q9NWQ6 B4DKN2 Q9UM44 D3DN60
Accessions EAW79727 EAW79728 Q9UM44 AF126162 AAD48396 AK000692 BAA91323 AK027132 AK097806 AK296644 BAG59244 AK315109 BC035971 AAH35971 BM980981 BP293912 DQ892610 ABM83536 DQ895850 ABM86776 XM_005247080 XP_005247137 XM_011512362 XP_011510664 XM_011512363 XP_011510665 XM_011512364 XP_011510666 XM_011512365 XP_011510667 XM_011512366 XP_011510668 XM_011512367 XP_011510669 XR_924094 XR_924095 NM_001282556 NP_001269485 NM_001282557 NP_001269486 NM_001282558 NP_001269487 NM_001282559 NP_001269488 NM_007072 NP_009003
Function Through interaction with TMIGD2, costimulates T-cells in the context of TCR-mediated activation. Enhances T-cell proliferation and cytokine production via an AKT-dependent signaling cascade. {ECO:0000269|PubMed:23784006}.
Subcellular Location Membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
Tissue Specificity Expressed at high levels in colon, kidney, testis, lung and pancreas, and at lower levels in small intestine, liver and skeletal muscle. In immune cells, highly expressed in B- cells, dendritic cells and macrophages. Not detected in T-cells. {ECO:0000269|PubMed:10444326, ECO:0000269|PubMed:23784006}.

HHLA2 CRISPR/Cas9 KO Plasmid (h) - sc-411576 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

HHLA2 HDR Plasmid (h) - sc-411576-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HHLA2 Double Nickase Plasmid (h) - sc-411576-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HHLA2 Double Nickase Plasmid (h2) - sc-411576-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HHLA2 CRISPR Activation Plasmid (h) - sc-411576-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

HHLA2 CRISPR Activation Plasmid (h2) - sc-411576-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

HHLA2 Lentiviral Activation Particles (h) - sc-411576-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HHLA2 Lentiviral Activation Particles (h2) - sc-411576-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HHLA2 siRNA (h) - sc-78498 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

HHLA2 shRNA Plasmid (h) - sc-78498-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

HHLA2 shRNA (h) Lentiviral Particles - sc-78498-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU079891 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN10022 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10022 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

HHLA2 siRNA (Human) - CRH7630 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

HHLA2 - MBS8211290 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human HHLA2 (NM_007072.2) - SHH312033 from Creative biogene

Category siRNA
Species Reactivities Human

Human HHLA2 siRNA - orb268132 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

HHLA2 shRNA Plasmid (Human) - CHH7630 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

HHLA2 miRNA 3'UTR clone - MiUTR1H-04491 from Creative biogene

Species Reactivities Human
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