BPI

Gene Symbol BPI
Entrez Gene 671
Alt Symbol BPIFD1, rBPI
Species Human
Gene Type protein-coding
Description bactericidal/permeability-increasing protein
Other Description BPI fold containing family D, member 1|CAP 57|bactericidal permeability-increasing protein|recombinant BPI holoprotein, rBPI
Swissprots B2RCY2 Q9UD65 P17213 Q9H1L2 Q5JRW0 Q9UCT4 Q9H203 Q9BYZ9 Q1ZZU8 Q9H1M8 Q8IW58
Accessions CAG28072 EAW76035 P17213 AF322588 AAG42844 AI436120 AK296568 BAG59188 AK315328 BAG37729 AX713278 CAD88641 AX746123 CAD97475 AX752831 CAD99178 BC032230 BC040955 AAH40955 BP306215 DQ414688 ABD66755 J04739 AAA51841 XM_005260522 XP_005260579 XM_011529012 XP_011527314 XR_430313 NM_001725 NP_001716
Function The cytotoxic action of BPI is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope. Has antibacterial activity against the Gram-nagative bacterium P.aeruginosa, this activity is inhibited by LPS from P.aeruginosa. {ECO:0000269|PubMed:1937776, ECO:0000269|PubMed:2722846}.
Subcellular Location Secreted. Cytoplasmic granule membrane. Note=Membrane-associated in polymorphonuclear Leukocytes (PMN) granules.
Tissue Specificity Restricted to cells of the myeloid series.

BPI (B-8) - sc-365309 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
BPI (B-8): sc-365309. Western blot analysis of BPI expression in HL-60 whole cell lysate.

BPI (D-3) - sc-514434 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
BPI (D-3): sc-514434. Western blot analysis of BPI expression in HL-60 (A) and AML-193 (B) whole cell lysates.

BPI (H-10) - sc-514212 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
BPI (H-10): sc-514212. Western blot analysis of BPI expression in HL-60 (A) and AML-193 (B) whole cell lysates.

BPI (H-130) - sc-33131 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
BPI (H-130): sc-33131. Western blot analysis of BPI expression in HL-60 (A) and CCRF-CEM (B) whole cell lysates.

BPI (D-20) - sc-23292 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
BPI (D-20): sc-23292. Western blot analysis of BPI expression in HL-60 whole cell lysate.

BPI (K-15) - sc-23293 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-BPI antibody - ab106113 from Abcam

Prices $370.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-BPI antibody [4E3] - ab90815 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 4E3

Anti-BPI antibody [EPR12350(B)] - ab175231 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR12350(B)
Immunofluorescent analysis of HL60 cells labeling BPI with ab175231 at 1/100 (red) and DAPI staining (blue).

Anti-Neutrophil Bactericidal Protein BP30 antibody - ab196732 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Neutrophil Bactericidal Protein BP30 antibody (ab196732) at 1/500 dilutionLane 1 : Jurkat cell extractLane 2 : HepG2 cell extractLane 3 : SK-Hep1 cell extractLane 4 : Mouse liver extractLane 5 : Mouse thymus extract

Anti-Neutrophil Bactericidal Protein BP30 antibody - ab187519 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of mouse lung tissue labelling Neutrophil Bactericidal Protein BP30 with ab187519 at 1/200. Magnification: 400x.

Anti-BPI Antibody (aa140-250, Biotin) - LS-C298418 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-BPI Antibody (aa320-452, FITC) - LS-C304700 from LifeSpan Bioscience

Prices $465.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-BPI Antibody (aa320-452, Biotin) - LS-C300290 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-BPI Antibody (aa140-250) - LS-C292966 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant BPI.

Anti-BPI Antibody (aa320-452) - LS-C292967 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant BPI.

Anti-BPI Antibody (aa301-331) - LS-C156847 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin-embedded human tonsil tissue reacted with BPI Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Anti-BPI Antibody (aa140-250, FITC) - LS-C305269 from LifeSpan Bioscience

Prices $435.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-BPI Antibody (aa199-487) - LS-C311592 from LifeSpan Bioscience

Prices $250.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-BPI Antibody - LS-C341579 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-BPI Antibody - LS-C333989 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry of paraffin-embedded mouse cancer using BPI antibody at dilution of 1:200 (400x lens).

Anti-BPI Antibody - LS-C125151 from LifeSpan Bioscience

Prices $740.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-BPI Antibody - LS-C125152 from LifeSpan Bioscience

Prices $740.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-BPI Antibody (clone 3F9) - LS-C139975 from LifeSpan Bioscience

Prices $665.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3F9

Anti-BPI Antibody - LS-C126975 from LifeSpan Bioscience

Prices $740.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
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