BPI

Gene Symbol	BPI
Entrez Gene	671
Alt Symbol	BPIFD1, rBPI
Species	Human
Gene Type	protein-coding
Description	bactericidal/permeability-increasing protein
Other Description	BPI fold containing family D, member 1|CAP 57|bactericidal permeability-increasing protein|recombinant BPI holoprotein, rBPI
Swissprots	B2RCY2 Q9UD65 P17213 Q9H1L2 Q5JRW0 Q9UCT4 Q9H203 Q9BYZ9 Q1ZZU8 Q9H1M8 Q8IW58
Accessions	CAG28072 EAW76035 P17213 AF322588 AAG42844 AI436120 AK296568 BAG59188 AK315328 BAG37729 AX713278 CAD88641 AX746123 CAD97475 AX752831 CAD99178 BC032230 BC040955 AAH40955 BP306215 DQ414688 ABD66755 J04739 AAA51841 XM_005260522 XP_005260579 XM_011529012 XP_011527314 XR_430313 NM_001725 NP_001716
Function	The cytotoxic action of BPI is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope. Has antibacterial activity against the Gram-nagative bacterium P.aeruginosa, this activity is inhibited by LPS from P.aeruginosa. {ECO:0000269|PubMed:1937776, ECO:0000269|PubMed:2722846}.
Subcellular Location	Secreted. Cytoplasmic granule membrane. Note=Membrane-associated in polymorphonuclear Leukocytes (PMN) granules.
Tissue Specificity	Restricted to cells of the myeloid series.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

BPI CRISPR/Cas9 KO Plasmid (h) - sc-404909 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

BPI HDR Plasmid (h) - sc-404909-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

BPI Double Nickase Plasmid (h) - sc-404909-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

BPI Double Nickase Plasmid (h2) - sc-404909-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

BPI CRISPR Activation Plasmid (h) - sc-404909-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

BPI CRISPR Activation Plasmid (h2) - sc-404909-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

BPI Lentiviral Activation Particles (h) - sc-404909-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

BPI Lentiviral Activation Particles (h2) - sc-404909-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

BPI siRNA (h) - sc-42738 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

BPI shRNA Plasmid (h) - sc-42738-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

BPI shRNA (h) Lentiviral Particles - sc-42738-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

MISSION® esiRNA - EHU024831 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN4037 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND4037 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR01913 from Sigma-Aldrich Category miRNA Prices $350.00 Sizes hutr01913

BPI siRNA (Human) - CRH0466 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

BPI - MBS8207703 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

BPI CRISPR/Cas9 KO Plasmid (h2) - sc-404909-KO-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

BPI HDR Plasmid (h2) - sc-404909-HDR-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

shRNA set against Human BPI (NM_001725.2) - SHH247446 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human BPI(NM_001725.2) - SHG103573 from Creative biogene Category siRNA Species Reactivities Human

Human BPI siRNA - orb260968 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

BPI shRNA Plasmid (Human) - CHH0466 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

BPI miRNA 3'UTR clone - MiUTR1H-00932 from Creative biogene Species Reactivities Human

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