BPI

Gene Symbol BPI
Entrez Gene 671
Alt Symbol BPIFD1, rBPI
Species Human
Gene Type protein-coding
Description bactericidal/permeability-increasing protein
Other Description BPI fold containing family D, member 1|CAP 57|bactericidal permeability-increasing protein|recombinant BPI holoprotein, rBPI
Swissprots B2RCY2 Q9UD65 P17213 Q9H1L2 Q5JRW0 Q9UCT4 Q9H203 Q9BYZ9 Q1ZZU8 Q9H1M8 Q8IW58
Accessions CAG28072 EAW76035 P17213 AF322588 AAG42844 AI436120 AK296568 BAG59188 AK315328 BAG37729 AX713278 CAD88641 AX746123 CAD97475 AX752831 CAD99178 BC032230 BC040955 AAH40955 BP306215 DQ414688 ABD66755 J04739 AAA51841 XM_005260522 XP_005260579 XM_011529012 XP_011527314 XR_430313 NM_001725 NP_001716
Function The cytotoxic action of BPI is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope. Has antibacterial activity against the Gram-nagative bacterium P.aeruginosa, this activity is inhibited by LPS from P.aeruginosa. {ECO:0000269|PubMed:1937776, ECO:0000269|PubMed:2722846}.
Subcellular Location Secreted. Cytoplasmic granule membrane. Note=Membrane-associated in polymorphonuclear Leukocytes (PMN) granules.
Tissue Specificity Restricted to cells of the myeloid series.

Human-BPI-cDNA-Clone - DC07388 from Abgent, a WuXi AppTec company

Prices $657.45
Sizes 10 µg
Species Human
Accession BC040955

BPI - MBS1275108 from MyBioSource

Prices $175.00
Sizes 10ug plasmid + 200ul glycerol stock
Species Human
Accession BC040955

Human BPI ORF Clone (BC040955) - CDCS410400 from Creative biogene

Species Human
Accession P17213

Human BPI ORF clone (BC040955) - CDCB159019 from Creative biogene

Species Human
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