Gene Symbol | BPI |
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Entrez Gene | 671 |
Alt Symbol | BPIFD1, rBPI |
Species | Human |
Gene Type | protein-coding |
Description | bactericidal/permeability-increasing protein |
Other Description | BPI fold containing family D, member 1|CAP 57|bactericidal permeability-increasing protein|recombinant BPI holoprotein, rBPI |
Swissprots | B2RCY2 Q9UD65 P17213 Q9H1L2 Q5JRW0 Q9UCT4 Q9H203 Q9BYZ9 Q1ZZU8 Q9H1M8 Q8IW58 |
Accessions | CAG28072 EAW76035 P17213 AF322588 AAG42844 AI436120 AK296568 BAG59188 AK315328 BAG37729 AX713278 CAD88641 AX746123 CAD97475 AX752831 CAD99178 BC032230 BC040955 AAH40955 BP306215 DQ414688 ABD66755 J04739 AAA51841 XM_005260522 XP_005260579 XM_011529012 XP_011527314 XR_430313 NM_001725 NP_001716 |
Function | The cytotoxic action of BPI is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope. Has antibacterial activity against the Gram-nagative bacterium P.aeruginosa, this activity is inhibited by LPS from P.aeruginosa. {ECO:0000269|PubMed:1937776, ECO:0000269|PubMed:2722846}. |
Subcellular Location | Secreted. Cytoplasmic granule membrane. Note=Membrane-associated in polymorphonuclear Leukocytes (PMN) granules. |
Tissue Specificity | Restricted to cells of the myeloid series. |
Human BPI ELISA Kit (Sandwich ELISA) - LS-F4494 from LifeSpan Bioscience
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Mouse BPI ELISA Kit (Sandwich ELISA) - LS-F7444 from LifeSpan Bioscience
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Human BPI ELISA Kit (Sandwich ELISA) - LS-F10957 from LifeSpan Bioscience
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BPI ELISA kit - 55R-ORG523 from Fitzgerald
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Human BPI ELISA Kit - abx054714 from Abbexa
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Human BPI ELISA Kit - abx150831 from Abbexa
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Anti-BPI, Human, ELISA - ORG 523 from ARP American Research Products
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Bactericidal permeability-increasing protein (BPI), Human, ELISA Kit - E01B0829 from ARP American Research Products
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Bactericidal permeability-increasing protein, BPI, Human, ELISA Kit - E1234h from ARP American Research Products
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Bactericidal/Permeability Increasing Protein (BPI), Human, ELISA Kit - SEB234Hu from ARP American Research Products
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Bactericidal/Permeability Increasing Protein, BPI, Human, ELISA Kit - E-EL-H0550 from ARP American Research Products
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Bactericidal/Permeability Increasing Protein, BPI, Rabbit, ELISA Kit - E-EL-RB1503 from ARP American Research Products
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Bactericidal/Permeability Increasing Protein, BPI, Chicken, ELISA Kit - E-EL-Ch0692 from ARP American Research Products
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Bactericidal/Permeability Increasing Protein, BPI, Porcine, ELISA Kit - E-EL-P0285 from ARP American Research Products
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Bactericidal/Permeability Increasing Protein, BPI, Sheep, ELISA Kit - E-EL-S0797 from ARP American Research Products
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Bactericidal/Permeability Increasing Protein, BPI, Guinea Pig, ELISA Kit - E-EL-GP1281 from ARP American Research Products
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Bactericidal/Permeability Increasing Protein, BPI, Monkey, ELISA Kit - E-EL-MK1278 from ARP American Research Products
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Human Anti-Bpi ELISA Kit - HB0692 from NeoScientific
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Human BPI(Bactericidal/Permeability Increasing Protein) ELISA Kit - E-EL-H0550 from Elabscience
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Human BPI (Bactericidal/Permeability Increasing Protein) CLIA Kit - E-CL-H0435 from Elabscience
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anti-Bactericidal permeability increasing protein antibody (BPI-Ab), ELISA Kit - MBS266768 from MyBioSource
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anti-Bactericidal permeability increasing protein antibody (BPI-Ab), ELISA Kit - MBS260906 from MyBioSource
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anti-Bactericidal permeability increasing protein antibody (BPI-Ab), ELISA Kit - MBS266309 from MyBioSource
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anti-Bactericidal permeability increasing protein antibody (BPI-Ab), ELISA Kit - MBS263002 from MyBioSource
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anti-Bactericidal permeability increasing protein antibody (BPI-Ab), ELISA Kit - MBS263536 from MyBioSource
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