DUSP3

Gene Symbol DUSP3
Entrez Gene 1845
Alt Symbol VHR
Species Human
Gene Type protein-coding
Description dual specificity phosphatase 3
Other Description dual specificity protein phosphatase 3|dual specificity protein phosphatase VHR|serine/threonine specific protein phosphatase|vaccinia H1-related phosphatase|vaccinia virus phosphatase VH1-related
Swissprots P51452 Q5U0J1 Q8IYJ9 D3DX45
Accessions EAW51667 EAW51668 P51452 AB451424 BAG70238 AK055834 AK129822 AK226170 AL049417 BC002682 AAH02682 BC008286 BC035701 AAH35701 BQ575811 BQ652984 BT019522 AAV38329 BU177084 DA075379 DA104250 DA167802 DB171573 DQ893122 ABM84048 DQ896399 ABM87398 L05147 AAA35777 NM_004090 NP_004081
Function Shows activity both for tyrosine-protein phosphate and serine-protein phosphate, but displays a strong preference toward phosphotyrosines. Specifically dephosphorylates and inactivates ERK1 and ERK2. {ECO:0000269|PubMed:10224087, ECO:0000269|PubMed:11863439}.
Subcellular Location Nucleus {ECO:0000269|PubMed:10224087}.
Top Pathways MAPK signaling pathway

DUSP3/VHR Antibody - 4752 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from HeLa, NIH/3T3, C6 and COS cells, using DUSP3/VHR Antibody.

VHR (F-2) - sc-374161 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
VHR (F-2): sc-374161. Western blot analysis of VHR expression in K-562 (A) and human PBL (B) whole cell lysates.

VHR (N-19) - sc-8889 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
VHR (N-19): sc-8889. Western blot analysis of VHR expression in non-transfected 293T: sc-117752 (A), human VHR transfected 293T: sc-170610 (B) and human PBL (C) whole cell lysates.

VHR (C-19) - sc-8890 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
VHR (C-19): sc-8890. Immunoperoxidase staining of formalin fixed, paraffin-embedded human ovary tissue showing nuclear staining of follicle cells and ovarian stroma cells.

VHR (H-55) - sc-366328 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
VHR (H-55): sc-366328. Western blot analysis of VHR expression in non-transfected: sc-117752 (A) and human VHR transfected: sc-170610 (B) 293T whole cell lysates.

VHR (24) - sc-136118 from Santa Cruz Biotechnology

Prices $279.00
Sizes 50 µg/0.5 ml
Host Mouse
Clonality Monoclonal
VHR (24): sc-136118. Western blot analysis of VHR expression in Jurkat whole cell lysate.

Anti-DUSP3 antibody - ab97453 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-DUSP3 antibody (ab97453) at 1/1000 dilution + 293T whole cell lysate at 30 µg

Anti-DUSP3 antibody - ab168428 from Abcam

Prices $370.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
All lanes : Anti-DUSP3 antibody (ab168428) at 1/500 dilutionLane 1 : DUSP3 transfected 293T lysate.Lane 2 : Non-transfected 293T lysate.Lysates/proteins at 15 µl per lane.

Anti-DUSP3 antibody - ab60228 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Ab60228 (1:50) staining human DUSP3 in human hepatocarcinoma tissue by immunohistochemistry formalin fixed paraffin embedded. Peroxidase conjugated to the secondary antibody followed by AEC staining. HC = hepatocarcinoma.

Anti-DUSP3 antibody - ab124475 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-DUSP3 antibody (ab124475) at 1/1000 dilutionLane 1 : HeLa cell lysateLane 2 : Human fetal spleen lysateLane 3 : Human fetal brain lysateLane 4 : Human fetal kidney lysate

Anti-DUSP3 antibody [ARM-1] - ab70902 from Abcam

Prices $370.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone ARM-1
All lanes : Anti-DUSP3 antibody [ARM-1] (ab70902) at 1/2000 dilutionLane 1 : HepG2 cell lysateLane 2 : Hep3B cell lysateLane 3 : U87mg cell lysateLane 4 : 293T cell lysate

Anti-DUSP3 antibody [EPR5492] - ab125077 from Abcam

Prices $313.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR5492
All lanes : Anti-DUSP3 antibody [EPR5492] (ab125077) at 1/50000 dilutionLane 1 : HeLa cell lysateLane 2 : Jurkat cell lysateLane 3 : MCF-7 cell lysateLane 4 : K562 cell lysateLysates/proteins at 10 µg per lane.SecondaryGoat anti-Rabbit HRP at 1/2000 dilution

Anti-DUSP3 antibody [MM0951-44T22] - ab201586 from Abcam

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone MM0951-44T22

Anti-DUSP3 antibody - C-terminal - ab190949 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-DUSP3 antibody - C-terminal (ab190949) at 0.5 µg/mlLane 1 : Rat testis tissue lysateLane 2 : SKOV cell lysateLane 3 : M453 cell lysate

Anti-DUSP3 antibody - C-terminal - ab190604 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-DUSP3 antibody - C-terminal (ab190604) at 1/500 dilution + HepG2 cell extract

Anti-DUSP3 / VHR Antibody (aa2-185) - LS-C314317 from LifeSpan Bioscience

Prices $415.00
Sizes 200 µg
Host Mouse
Clonality Monoclonal
Western blot of recombinant DUSP3 / VHR.

Anti-DUSP3 / VHR Antibody (aa155-171) - LS-C312909 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
WB of DUSP3 / VHR antibody. All lanes: Anti-DUSP3 at 0.5ug/ml. Lane 1: Rat Testis Tissue Lysate at 40ug. Lane 2: SKOV Whole Cell Lysate at 40ug. Lane 3: MM453 Whole Cell Lysate at 40ug. Predicted bind size: 20KD. Observed bind size: 20KD.

Anti-DUSP3 / VHR Antibody (aa1-185) - LS-C186048 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded N87 xenograft using DUSP3 antibody at 1:500 dilution.

Anti-DUSP3 / VHR Antibody - LS-C76847 from LifeSpan Bioscience

Prices $465.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-DUSP3 / VHR Antibody - LS-C76848 from LifeSpan Bioscience

Prices $465.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-DUSP3 / VHR Antibody - LS-C62105 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal

Anti-DUSP3 / VHR Antibody (C-Terminus, APC) - LS-C225199 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DUSP3 / VHR Antibody (clone 2C4) - LS-C139514 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2C4
Detection limit for recombinant GST tagged DUSP3 is 0.3 ng/ml as a capture antibody.

Anti-DUSP3 / VHR Antibody (aa2-144) - LS-C178926 from LifeSpan Bioscience

Prices $255.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-DUSP3 / VHR Antibody (C-Terminus, AP) - LS-C225200 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
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