DUSP3

Gene Symbol	DUSP3
Entrez Gene	1845
Alt Symbol	VHR
Species	Human
Gene Type	protein-coding
Description	dual specificity phosphatase 3
Other Description	dual specificity protein phosphatase 3|dual specificity protein phosphatase VHR|serine/threonine specific protein phosphatase|vaccinia H1-related phosphatase|vaccinia virus phosphatase VH1-related
Swissprots	P51452 Q5U0J1 Q8IYJ9 D3DX45
Accessions	EAW51667 EAW51668 P51452 AB451424 BAG70238 AK055834 AK129822 AK226170 AL049417 BC002682 AAH02682 BC008286 BC035701 AAH35701 BQ575811 BQ652984 BT019522 AAV38329 BU177084 DA075379 DA104250 DA167802 DB171573 DQ893122 ABM84048 DQ896399 ABM87398 L05147 AAA35777 NM_004090 NP_004081
Function	Shows activity both for tyrosine-protein phosphate and serine-protein phosphate, but displays a strong preference toward phosphotyrosines. Specifically dephosphorylates and inactivates ERK1 and ERK2. {ECO:0000269|PubMed:10224087, ECO:0000269|PubMed:11863439}.
Subcellular Location	Nucleus {ECO:0000269|PubMed:10224087}.
Top Pathways	MAPK signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

DUSP3-Over-expression-Lysate - LY10563a from Abgent, a WuXi AppTec company Category Cell Lysate Prices $325.00 Sizes 100 µg

DUSP3 293T Cell Transient Overexpression Lysate(Denatured) - H00001845-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

DUSP3 293 Cell Lysate - 401210 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

VHR/DUSP3 Overexpression Lysate (Denatured) - H00001845-T01 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

VHR/DUSP3 Overexpression Lysate (Native) - NBL1-10053 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

VHR (h): 293T Lysate - sc-170129 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

VHR (h2): 293T Lysate - sc-170610 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

VHR (h3): 293T Lysate - sc-159087 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

VHR (h4): 293T Lysate - sc-159088 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

DUSP3 Over-expression Lysate Product - GWB-EF7D1F from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

Human DUSP3 / VHR Insect Cell Lysate (WB positive control) - 10114-HNCBL-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Human

Human DUSP3 / VHR Insect Cell Lysate (WB positive control) - 10114-H20BL-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Human

Human DUSP3 Baculovirus-Insect Cells Transfected Lysate (positive control) (denatured) - orb175046 from Biorbyt Category Cell Lysate Prices $425.00 Sizes 300 μg Species Human

Human DUSP3 Baculovirus-Insect Cells Transfected Lysate (positive control) (denatured) - orb175284 from Biorbyt Category Cell Lysate Prices $604.00 Sizes 300 μg Species Human

Panoply™ Human DUSP3 Knockdown Stable Cell Line - CSC-DC004615 from Creative biogene Category Cell Line Species Human

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