DUSP3

Gene Symbol	DUSP3
Entrez Gene	1845
Alt Symbol	VHR
Species	Human
Gene Type	protein-coding
Description	dual specificity phosphatase 3
Other Description	dual specificity protein phosphatase 3|dual specificity protein phosphatase VHR|serine/threonine specific protein phosphatase|vaccinia H1-related phosphatase|vaccinia virus phosphatase VH1-related
Swissprots	P51452 Q5U0J1 Q8IYJ9 D3DX45
Accessions	EAW51667 EAW51668 P51452 AB451424 BAG70238 AK055834 AK129822 AK226170 AL049417 BC002682 AAH02682 BC008286 BC035701 AAH35701 BQ575811 BQ652984 BT019522 AAV38329 BU177084 DA075379 DA104250 DA167802 DB171573 DQ893122 ABM84048 DQ896399 ABM87398 L05147 AAA35777 NM_004090 NP_004081
Function	Shows activity both for tyrosine-protein phosphate and serine-protein phosphate, but displays a strong preference toward phosphotyrosines. Specifically dephosphorylates and inactivates ERK1 and ERK2. {ECO:0000269|PubMed:10224087, ECO:0000269|PubMed:11863439}.
Subcellular Location	Nucleus {ECO:0000269|PubMed:10224087}.
Top Pathways	MAPK signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

VHR CRISPR/Cas9 KO Plasmid (h) - sc-405733 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

VHR HDR Plasmid (h) - sc-405733-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

VHR Double Nickase Plasmid (h) - sc-405733-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

VHR Double Nickase Plasmid (h2) - sc-405733-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

VHR CRISPR Activation Plasmid (h) - sc-405733-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

VHR CRISPR Activation Plasmid (h2) - sc-405733-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

VHR Lentiviral Activation Particles (h) - sc-405733-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

VHR Lentiviral Activation Particles (h2) - sc-405733-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

VHR siRNA (h) - sc-39006 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

VHR shRNA Plasmid (h) - sc-39006-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

VHR shRNA (h) Lentiviral Particles - sc-39006-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

VHR/DUSP3 RNAi - H00001845-R01 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU143681 from Sigma-Aldrich Category siRNA Prices $250.00 Sizes 50 µg

MISSION® Human Phosphatase - SIHP0134 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 250 pmol

MISSION® Human Phosphatase - SIHP0133 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 250 pmol

MISSION® Human Phosphatase - SIHP0135 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 250 pmol

CompoZr® Knockout ZFN Kit - CKOZFN7557 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7557 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

DUSP3 siRNA (Human) - CRH1293 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

DUSP3 - MBS8228691 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

VHR CRISPR/Cas9 KO Plasmid (h2) - sc-405733-KO-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

VHR HDR Plasmid (h2) - sc-405733-HDR-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

shRNA set against Human DUSP3 (NM_004090.3) - SHH281861 from Creative biogene Category siRNA Species Reactivities Human

Human DUSP3 siRNA - orb261795 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

DUSP3 shRNA Plasmid (Human) - CHH1293 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

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