DUSP3

Gene Symbol	DUSP3
Entrez Gene	1845
Alt Symbol	VHR
Species	Human
Gene Type	protein-coding
Description	dual specificity phosphatase 3
Other Description	dual specificity protein phosphatase 3|dual specificity protein phosphatase VHR|serine/threonine specific protein phosphatase|vaccinia H1-related phosphatase|vaccinia virus phosphatase VH1-related
Swissprots	P51452 Q5U0J1 Q8IYJ9 D3DX45
Accessions	EAW51667 EAW51668 P51452 AB451424 BAG70238 AK055834 AK129822 AK226170 AL049417 BC002682 AAH02682 BC008286 BC035701 AAH35701 BQ575811 BQ652984 BT019522 AAV38329 BU177084 DA075379 DA104250 DA167802 DB171573 DQ893122 ABM84048 DQ896399 ABM87398 L05147 AAA35777 NM_004090 NP_004081
Function	Shows activity both for tyrosine-protein phosphate and serine-protein phosphate, but displays a strong preference toward phosphotyrosines. Specifically dephosphorylates and inactivates ERK1 and ERK2. {ECO:0000269|PubMed:10224087, ECO:0000269|PubMed:11863439}.
Subcellular Location	Nucleus {ECO:0000269|PubMed:10224087}.
Top Pathways	MAPK signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human DUSP3 full length protein - ab168010 from Abcam Category Protein Prices $410.00 Sizes 100 µg Source E. coli Species Human

Active human DUSP3 full length protein - ab90613 from Abcam Category Protein Prices $302.00 Sizes 20 µg Source E. coli Species Human

Human DUSP3 full length protein - ab113160 from Abcam Category Protein Source E. coli Species Human

DUSP3 / VHR Antibody Blocking Peptide - LS-E9602 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

VHR/DUSP3 Partial Recombinant Protein - H00001845-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human VHR/DUSP3 Protein - H00001845-P02 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

VHR/DUSP3 Recombinant Protein - H00001845-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human VHR/DUSP3 Protein - NBP1-72478 from Novus Biologicals Category Protein Prices $269.00, $729.00 Sizes 100 µg, 500 µg Source E. coli Species Human

VHR/DUSP3 Peptide - P3333 from Novus Biologicals Category Peptide Species Human

DUSP3-Antibody-N-term-Blocking-Peptide - BP8478a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

DUSP3 Protein - GTX109149-pro from GeneTex Category Protein Prices $299.00 Sizes 25 μg Source E. coli Species Human

Recombinant Human VHR, CF - 1654-VH-050 from R&D Systems Category Protein Source E. coli-derived, Ser2-Pro185, with an N-terminal Met and 6-His tag

Human DUSP3 protein - orb168256 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 20 μg Species Human

Human DUSP3 His GST tag protein - orb84443 from Biorbyt Category Protein Prices $400.00, $612.00 Sizes 50 μg, 100 μg Source Insect Species Human

Human DUSP3 protein - orb138718 from Biorbyt Category Protein Prices $400.00, $612.00 Sizes 50 μg, 100 μg Source Baculovirus-Insect Cells Species Human

DUSP3 protein (His tag) - 80R-1992 from Fitzgerald Category Protein Prices $275.00 Sizes 100 µg Source E.coli

Human DUSP3 Protein - abx066364 from Abbexa Category Protein Source E.coli Species Human

DUSP3 (1-185, His-tag) - AR50062PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

DUSP3 (1-185, His-tag) - AR50062PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

DUSP3 - H00001845-P01-02 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Source in vitro transl. Species Human

DUSP3 - H00001845-P02 from Acris Antibodies Category Protein Prices $370.00 Sizes 10 µg Species Human

DUSP3 - H00001845-P02-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

DUSP3 - H00001845-P02-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

DUSP3 - H00001845-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

DUSP3 - H00001845-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

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