Gene Symbol | DUSP3 |
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Entrez Gene | 1845 |
Alt Symbol | VHR |
Species | Human |
Gene Type | protein-coding |
Description | dual specificity phosphatase 3 |
Other Description | dual specificity protein phosphatase 3|dual specificity protein phosphatase VHR|serine/threonine specific protein phosphatase|vaccinia H1-related phosphatase|vaccinia virus phosphatase VH1-related |
Swissprots | P51452 Q5U0J1 Q8IYJ9 D3DX45 |
Accessions | EAW51667 EAW51668 P51452 AB451424 BAG70238 AK055834 AK129822 AK226170 AL049417 BC002682 AAH02682 BC008286 BC035701 AAH35701 BQ575811 BQ652984 BT019522 AAV38329 BU177084 DA075379 DA104250 DA167802 DB171573 DQ893122 ABM84048 DQ896399 ABM87398 L05147 AAA35777 NM_004090 NP_004081 |
Function | Shows activity both for tyrosine-protein phosphate and serine-protein phosphate, but displays a strong preference toward phosphotyrosines. Specifically dephosphorylates and inactivates ERK1 and ERK2. {ECO:0000269|PubMed:10224087, ECO:0000269|PubMed:11863439}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:10224087}. |
Top Pathways | MAPK signaling pathway |
dual specificity phosphatase 3, ELISA Kit - MBS9327347 from MyBioSource
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DUSP3 ELISA Kit (Human) (OKEH02215) - OKEH02215 from Aviva Systems Biology
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Custom Human VHR ELISA - ELH-VHR-1 from RayBiotech
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Human DUSP3 ELISA Kit - E012451 from Biobool
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Human Dual specificity protein phosphatase 3 ELISA Kit - EK3006 from Signalway Antibody
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anti-DUSP3 antibody [9E6] - ARG57052 from Arigo Biolaboratories
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Dual specificity protein phosphatase 3, ELISA Kit - MBS2887773 from MyBioSource
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Dual specificity protein phosphatase 3, ELISA Kit - MBS9426841 from MyBioSource
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Dual specificity protein phosphatase 3, ELISA Kit - MBS2887898 from MyBioSource
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