DCX

Gene Symbol	DCX
Entrez Gene	1641
Alt Symbol	DBCN, DC, LISX, SCLH, XLIS
Species	Human
Gene Type	protein-coding
Description	doublecortin
Other Description	doublecortex|doublin|lis-X|lissencephalin-X|neuronal migration protein doublecortin
Swissprots	Q5JYZ5 D3DUY9 O43911 D3DUY8 A6NFY6 O43602 A9Z1V8 D3DUZ0
Accessions	CAA06617 EAX02642 EAX02643 EAX02644 EAX02645 EAX02646 EAX02647 EAX02648 EAX02649 O43602 AF034634 AAC52037 AF040254 AAC31797 AF040255 AAC31696 AJ003112 CAA05867 AK002120 AK290455 BAF83144 AK297297 BAG59765 AK299822 BAG61691 AU120758 AW163329 BC027925 AAH27925 DA497601 DC375659 HQ447825 ADQ32309 XM_011530878 XP_011529180 XM_011530879 XP_011529181 XM_011530880 XP_011529182 NM_000555 NP_000546 NM_001195553 NP_001182482 NM_178151 NP_835364 NM_178152 NP_835365 NM_178153 NP_835366
Function	Microtubule-associated protein required for initial steps of neuronal dispersion and cortex lamination during cerebral cortex development. May act by competing with the putative neuronal protein kinase DCLK1 in binding to a target protein. May in that way participate in a signaling pathway that is crucial for neuronal interaction before and during migration, possibly as part of a calcium ion-dependent signal transduction pathway. May be part with PAFAH1B1/LIS-1 of overlapping, but distinct, signaling pathways that promote neuronal migration. {ECO:0000269|PubMed:22359282}.
Subcellular Location	Cytoplasm. Cell projection {ECO:0000250}. Note=Localizes at neurite tips. {ECO:0000250}.
Tissue Specificity	Highly expressed in neuronal cells of fetal brain (in the majority of cells of the cortical plate, intermediate zone and ventricular zone), but not expressed in other fetal tissues. In the adult, highly expressed in the brain frontal lobe, but very low expression in other regions of brain, and not detected in heart, placenta, lung, liver, skeletal muscles, kidney and pancreas.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human DCX / Doublecortin ELISA Kit (Sandwich ELISA) - LS-F6199 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 0.156 ng/ml Range 0.156-10 ng/ml

Mouse/Human/Rat DCX / Doublecortin ELISA Kit (Cell-Based ELISA) - LS-F1946 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate Range 0.156-10 ng/ml

Mouse DCX / Doublecortin ELISA Kit (Sandwich ELISA) - LS-F7562 from LifeSpan Bioscience Category ELISA Kit Prices $740.00 Sizes 1 plate Sensitivity 0.061 ng/ml Range 0.156-10 ng/ml

Rat DCX / Doublecortin ELISA Kit (Sandwich ELISA) - LS-F7708 from LifeSpan Bioscience Category ELISA Kit Prices $780.00 Sizes 1 plate Sensitivity 0.054 ng/ml Range 0.156-10 ng/ml

Human Doublecortin ELISA Kit - abx151342 from Abbexa Category ELISA Kit Sensitivity 0.058 ng/ml Range 0.156 ng/ml - 10 ng/ml

Doublecortin, DCX, Human, ELISA Kit - E-EL-H2033 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 0.094 Range 0.156-10ng/mL

Doublecortin (DCX), Human, ELISA Kit - SEC442Hu from ARP American Research Products Category ELISA Kit Prices $720.00 Sizes 96 t Sensitivity 0.058ng/mL Range 0.156-10ng/mL

Doublecortin, Human, ELISA Kit - E01D0148 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t Sensitivity 0.1ng/ml Range 0.5-10ng/mL,

Doublecortin, DCX, Rabbit, ELISA Kit - E-EL-RB0795 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Doublecortin, DCX, Chicken, ELISA Kit - E-EL-Ch0334 from ARP American Research Products Category ELISA Kit Prices $445.50 Sizes 96 t

Doublecortin, DCX, Porcine, ELISA Kit - E-EL-P0546 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Doublecortin, DCX, Sheep, ELISA Kit - E-EL-S0022 from ARP American Research Products Category ELISA Kit Prices $648.00 Sizes 96 t

Doublecortin, DCX, Guinea Pig, ELISA Kit - E-EL-GP0368 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t

Doublecortin, DCX, Monkey, ELISA Kit - E-EL-MK2018 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Human DCX ELISA Kit - HD0155 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Anserine DCX ELISA Kit - AD0155 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

DCX, ELISA Kit - MBS2513446 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.094ng/mL Range 0.156-10ng/mL

DCX, ELISA Kit - MBS2512442 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 18.75pg/mL Range 31.25-2000pg/mL

DCX, ELISA Kit - MBS2515516 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

DCX, ELISA Kit - MBS2502721 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 37.5pg/mL Range 62.5-4000pg/mL

DCX, ELISA Kit - MBS2505551 from MyBioSource Category ELISA Kit Prices $490.00, $585.00, $2,475.00, $4,360.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 18.75pg/mL Range 31.25-2000pg/mL

DCX, ELISA Kit - MBS2511213 from MyBioSource Category ELISA Kit Prices $410.00, $490.00, $2,040.00, $3,590.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.094ng/mL Range 0.156--10ng/mL

DCX, ELISA Kit - MBS2503322 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.094ng/mL Range 0.156-10ng/mL

Doublecortin, ELISA Kit - MBS040903 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Doublecortin, ELISA Kit - MBS026580 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

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