DCX

Gene Symbol	DCX
Entrez Gene	1641
Alt Symbol	DBCN, DC, LISX, SCLH, XLIS
Species	Human
Gene Type	protein-coding
Description	doublecortin
Other Description	doublecortex|doublin|lis-X|lissencephalin-X|neuronal migration protein doublecortin
Swissprots	Q5JYZ5 D3DUY9 O43911 D3DUY8 A6NFY6 O43602 A9Z1V8 D3DUZ0
Accessions	CAA06617 EAX02642 EAX02643 EAX02644 EAX02645 EAX02646 EAX02647 EAX02648 EAX02649 O43602 AF034634 AAC52037 AF040254 AAC31797 AF040255 AAC31696 AJ003112 CAA05867 AK002120 AK290455 BAF83144 AK297297 BAG59765 AK299822 BAG61691 AU120758 AW163329 BC027925 AAH27925 DA497601 DC375659 HQ447825 ADQ32309 XM_011530878 XP_011529180 XM_011530879 XP_011529181 XM_011530880 XP_011529182 NM_000555 NP_000546 NM_001195553 NP_001182482 NM_178151 NP_835364 NM_178152 NP_835365 NM_178153 NP_835366
Function	Microtubule-associated protein required for initial steps of neuronal dispersion and cortex lamination during cerebral cortex development. May act by competing with the putative neuronal protein kinase DCLK1 in binding to a target protein. May in that way participate in a signaling pathway that is crucial for neuronal interaction before and during migration, possibly as part of a calcium ion-dependent signal transduction pathway. May be part with PAFAH1B1/LIS-1 of overlapping, but distinct, signaling pathways that promote neuronal migration. {ECO:0000269|PubMed:22359282}.
Subcellular Location	Cytoplasm. Cell projection {ECO:0000250}. Note=Localizes at neurite tips. {ECO:0000250}.
Tissue Specificity	Highly expressed in neuronal cells of fetal brain (in the majority of cells of the cortical plate, intermediate zone and ventricular zone), but not expressed in other fetal tissues. In the adult, highly expressed in the brain frontal lobe, but very low expression in other regions of brain, and not detected in heart, placenta, lung, liver, skeletal muscles, kidney and pancreas.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

DCX-Over-expression-Lysate - LY11440a from Abgent, a WuXi AppTec company Category Cell Lysate Prices $325.00 Sizes 100 µg

DCX 293T Cell Transient Overexpression Lysate(Denatured) - H00001641-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

DCX HEK293 Cell Transient Overexpression Lysate (Non-Denatured) - L049T6 from Acris Antibodies Category Cell Lysate Prices $290.00 Sizes 100 µg

DCX overexpression lysate - LY403598 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

DCX overexpression lysate - LY405947 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

DCX overexpression lysate - LY424646 from Acris Antibodies Category Cell Lysate Prices $480.00 Sizes 100 µg

DCX overexpression lysate - LY425000 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

DCX 293 Cell Lysate - 403769 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

DCX 293 Cell Lysate - 403108 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

Doublecortin Overexpression Lysate (Denatured) - H00001641-T01 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

Doublecortin Overexpression Lysate (Native) - NBL1-09761 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

Doublecortin Overexpression Lysate (Native) - NBL1-09760 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

Doublecortin (h): 293T Lysate - sc-114231 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

DCX Over-expression Lysate Product - GWB-68920D from Genway Biotech Category Cell Lysate Prices $445.00 Sizes 100 µg Species Human

DCX Over-expression Lysate Product - GWB-24E3AD from Genway Biotech Category Cell Lysate Prices $445.00 Sizes 100 µg Species Human

Doublecortin Overexpression Lysate (Native) - NBP2-04984 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

Doublecortin Overexpression Lysate (Native) - NBP2-10681 from Novus Biologicals Category Cell Lysate Prices $529.00 Sizes 100 µg

Doublecortin Overexpression Lysate (Native) - NBP2-11166 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

Panoply™ Human DCX Knockdown Stable Cell Line - CSC-DC004111 from Creative biogene Category Cell Line Species Human

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