MZB1

Gene Symbol MZB1
Entrez Gene 51237
Alt Symbol MEDA-7, PACAP, pERp1
Species Human
Gene Type protein-coding
Description marginal zone B and B1 cell-specific protein
Other Description HSPC190|caspase-2 binding protein|marginal zone B- and B1-cell-specific protein|mesenteric estrogen-dependent adipose 7|mesenteric oestrogen-dependent adipose gene- 7|plasma cell-induced ER protein 1|plasma cell-induced resident ER protein|plasma cell-induced resident endoplasmic reticulum protein|proapoptotic caspase adapter protein|proapoptotic caspase adaptor protein
Swissprots Q9P0T3 Q96RL5 Q7Z6N2 Q8WU39 D2IYS0
Accessions Q8WU39 AA837360 AF151024 AAF36110 AF338109 AAK84085 AK057549 BAG51934 AK292706 BAF85395 BC009931 AAH09931 BC021275 AAH21275 BU601458 DQ892627 ABM83553 EU176703 ABW03504 GQ477350 ACY74343 NM_016459 NP_057543
Function Associates with immunoglobulin M (IgM) heavy and light chains and promotes IgM assembly and secretion. May exert its effect by acting as a molecular chaperone or as an oxidoreductase as it displays a low level of oxidoreductase activity (By similarity). Isoform 2 may be involved in regulation of apoptosis. Helps to diversify peripheral B-cell functions by regulating Ca(2+) stores, antibody secretion and integrin activation. {ECO:0000250}.
Subcellular Location Isoform 1: Endoplasmic reticulum lumen {ECO:0000255|PROSITE-ProRule:PRU10138}. Secreted.
Tissue Specificity Widely expressed with highest levels in adult brain, small intestine and lymphoid tissues such as thymus and spleen. Expression is frequently lower in intestinal-type gastric cancer. In obese patients, more abundant in omental than in subcutaneous fat. {ECO:0000269|PubMed:11350957, ECO:0000269|PubMed:12792799, ECO:0000269|PubMed:19805157}.

MGC29506 (D-15) - sc-168603 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
MGC29506 (D-15): sc-168603. Western blot analysis of MGC29506 expression in Raji whole cell lysate.

MGC29506 (S-15) - sc-168604 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
MGC29506 (S-15): sc-168604. Western blot analysis of MGC29506 expression in K-562 whole cell lysate.

MGC29506 (T-13) - sc-168605 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-Proapoptotic Caspase Adaptor Protein antibody [EPR11543(B)] - ab170891 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR11543(B)
Western blot analysis on immunoprecipitation pellet from (1) Raji cell lysate or (2) 1X PBS (negative control) immunoprecipitated using ab170891 at 1/10 dilution. Detection utilized HRP-conjugated anti-rabbit IgG which preferentially detects the non-reduced form of rabbit IgG.

Anti-Proapoptotic Caspase Adaptor Protein antibody [EPR11544] - ab181205 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR11544
All lanes : Anti-Proapoptotic Caspase Adaptor Protein antibody [EPR11544] (ab181205) at 1/50000 dilutionLane 1 : Raji cell lysateLane 2 : Ramos cell lysateLane 3 : Molt-4 cell lysateLysates/proteins at 20 µg per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution

Anti-Proapoptotic Caspase Adaptor Protein antibody - ab96308 from Abcam

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Proapoptotic Caspase Adaptor Protein antibody (ab96308) at 1/1000 dilutionLane 1 : MOLT4 whole cell lysateLane 2 : Raji whole cell lysateLysates/proteins at 30 µg per lane.

Anti-Proapoptotic Caspase Adaptor Protein antibody - ab67021 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-Proapoptotic Caspase Adaptor Protein antibody (ab67021) at 1/500 dilutionLane 1 : Transfected 293T cell lysateLane 2 : non Transfected 293T cell lysateLysates/proteins at 25 µg per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/5000 dilution

Proapoptotic Caspase Adaptor Protein Antibody - NBP1-92287 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: Proapoptotic Caspase Adaptor Protein Antibody [NBP1-92287] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG sp. Lane 4: Human plasma (IgG/HSA depleted). Lane 5: Human liver tissue. Lane 6: Human tonsil tissue

Proapoptotic Caspase Adaptor Protein Antibody - H00051237-B02 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: Proapoptotic Caspase Adaptor Protein Antibody [H00051237-B02] - analysis of PACAP expression in transfected 293T cell line by PACAP MaxPab polyclonal antibody (B02). Lane 1: PACAP transfected lysate (20.70 KDa). Lane 2: Non-transfected lysate.

Proapoptotic Caspase Adaptor Protein Antibody - NBP1-31619 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: Proapoptotic Caspase Adaptor Protein Antibody [NBP1-31619] - Sample(30 ug whole cell lysate)A:MOLT4 B:Raji 15% SDS PAGE, antibody diluted at 1:1000.

Proapoptotic Caspase Adaptor Protein Antibody - H00051237-B02P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: Proapoptotic Caspase Adaptor Protein Antibody [H00051237-B02P] - Analysis of MGC29506 expression in transfected 293T cell line by MGC29506 polyclonal antibody. Lane 1: PACAP transfected lysate(20.79 KDa). Lane 2: Non-transfected lysate.

Proapoptotic Caspase Adaptor Protein Antibody - H00051237-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-MGC29506 (PACAP) (96-110) antibody produced in rabbit - SAB1101600 from Sigma-Aldrich

Prices $328.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Anti-MGC29506 (PACAP) (96-110) (RB): <B>Cat. No. SAB1101600</B>: Immunofluorescence of HUVEC cells using Anti-MGC29506 (PACAP) (96-110) (RB) at a 1:50 dilution, taken at 40× magnification and nuclear staining with Hoescht 33342 (blue). Yale HTCB IF procedure used. Images may have been adjusted to improve viewing quality. If you would like the original image, please send a request to protocols@sial.com

Anti-MGC29506 (PACAP) (151-165) antibody produced in rabbit - SAB1101601 from Sigma-Aldrich

Prices $328.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Anti-MGC29506 (PACAP) (151-165) (RB): <B>Cat. No. SAB1101601</B>: Immunofluorescence of HUVEC cells using Anti-MGC29506 (PACAP) (151-165) (RB) at a 1:50 dilution, taken at 40× magnification and nuclear staining with Hoescht 33342 (blue). Yale HTCB IF procedure used. Images may have been adjusted to improve viewing quality. If you would like the original image, please send a request to protocols@sial.com

Anti-MGC29506 antibody produced in mouse - SAB1409405 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-MGC29506: <B>Cat. No. SAB1409405</B>: Antibody concentration: 0.1-5 μg/mL. Specific band of ~20.8 kDa using MGC29506 transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

Anti-RP11-1280I22.1 antibody produced in rabbit - HPA043745 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-RP11-1280I22.1: <B>Cat. No. HPA043745</B>: Immunohistochemical staining of human tonsil shows strong cytoplasmic positivity in subsets of germinal and non-germinal center cells.

Anti-PACAP antibody produced in mouse - SAB1407463 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-PACAP: <B>Cat. No. SAB1407463</B>: Antibody concentration: 0.1-5 μg/mL. Specific band of ~20.9 kDa using MGC29506 transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

PACAP antibody - GTX37576 from GeneTex

Prices $319.00
Sizes 100 μg
Host Rabbit
Clonality Polyclonal
Anti-PACAP antibody used in Western blot. GTX37576

PACAP antibody [N1C3] - GTX106794 from GeneTex

Prices $119.00
Sizes 25 μl
Host Rabbit
Clonality Polyclonal
Anti-PACAP antibody [N1C3] used in IHC (Formalin-fixed paraffin-embedded sections). GTX106794

PACAP antibody - 70R-13037 from Fitzgerald

Prices $395.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

MZB1 antibody (OAGA00534) - OAGA00534 from Aviva Systems Biology

Prices $340.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

PACAP antibody - orb69886 from Biorbyt

Prices $723.00
Sizes 100 μl
Host Rabbit
Clonality Polyclonal
Western Blot analysis of A:MOLT4, B:Raji whole cell lysate using PACAP antibody

PACAP antibody - 11454-1-AP from Acris Antibodies

Prices $270.00
Sizes 150 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry of paraffin-embedded Gliomas using 11454-1-AP(MGC29506 Antibody) at Dilution 1:50 (under 40x lens)

PACAP antibody - H00051237-B01P from Acris Antibodies

Prices $360.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot analysis of MGC29506 expression in transfected 293T cell line (H00051237-T01) by MGC29506 MaxPab polyclonal antibody.Lane 1: PAC

PACAP antibody - H00051237-B02 from Acris Antibodies

Prices $360.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot analysis of MGC29506 expression in transfected 293T cell line (H00051237-T02) by MGC29506 MaxPab polyclonal antibody.Lane 1: PAC
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