MZB1

Gene Symbol	MZB1
Entrez Gene	51237
Alt Symbol	MEDA-7, PACAP, pERp1
Species	Human
Gene Type	protein-coding
Description	marginal zone B and B1 cell-specific protein
Other Description	HSPC190|caspase-2 binding protein|marginal zone B- and B1-cell-specific protein|mesenteric estrogen-dependent adipose 7|mesenteric oestrogen-dependent adipose gene- 7|plasma cell-induced ER protein 1|plasma cell-induced resident ER protein|plasma cell-induced resident endoplasmic reticulum protein|proapoptotic caspase adapter protein|proapoptotic caspase adaptor protein
Swissprots	Q9P0T3 Q96RL5 Q7Z6N2 Q8WU39 D2IYS0
Accessions	Q8WU39 AA837360 AF151024 AAF36110 AF338109 AAK84085 AK057549 BAG51934 AK292706 BAF85395 BC009931 AAH09931 BC021275 AAH21275 BU601458 DQ892627 ABM83553 EU176703 ABW03504 GQ477350 ACY74343 NM_016459 NP_057543
Function	Associates with immunoglobulin M (IgM) heavy and light chains and promotes IgM assembly and secretion. May exert its effect by acting as a molecular chaperone or as an oxidoreductase as it displays a low level of oxidoreductase activity (By similarity). Isoform 2 may be involved in regulation of apoptosis. Helps to diversify peripheral B-cell functions by regulating Ca(2+) stores, antibody secretion and integrin activation. {ECO:0000250}.
Subcellular Location	Isoform 1: Endoplasmic reticulum lumen {ECO:0000255|PROSITE-ProRule:PRU10138}. Secreted.
Tissue Specificity	Widely expressed with highest levels in adult brain, small intestine and lymphoid tissues such as thymus and spleen. Expression is frequently lower in intestinal-type gastric cancer. In obese patients, more abundant in omental than in subcutaneous fat. {ECO:0000269|PubMed:11350957, ECO:0000269|PubMed:12792799, ECO:0000269|PubMed:19805157}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

PACAP 293T Cell Transient Overexpression Lysate(Denatured) - H00051237-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

PACAP 293T Cell Transient Overexpression Lysate(Denatured) - H00051237-T02 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

MZB1 overexpression lysate - LY402553 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

MGC29506 293 Cell Lysate - 402234 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg Tissue Plasma

Proapoptotic Caspase Adaptor Protein Overexpression Lysate (Denatured) - H00051237-T01 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

Proapoptotic Caspase Adaptor Protein Overexpression Lysate (Native) - NBL1-13064 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

MGC29506 Over-expression Lysate Product - GWB-83C544 from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

Human PERP1 / MZB1 HEK293 Cell Lysate (WB positive control) - 15682-H02HL-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Human

Human MZB1 / PERP1 HEK293 Cell Lysate (WB positive control) - 15682-H08HL-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Human

Human PERP1 Human Cells Transfected Lysate (positive control) (denatured) - orb233047 from Biorbyt Category Cell Lysate Prices $425.00 Sizes 300 μg Species Human

Human MZB1 Human Cells Transfected Lysate (positive control) (denatured) - orb174636 from Biorbyt Category Cell Lysate Prices $425.00 Sizes 300 μg Species Human

Proapoptotic Caspase Adaptor Protein Overexpression Lysate (Denatured) - H00051237-T02 from Novus Biologicals Category Cell Lysate Prices $299.00 Sizes 100 µl

Panoply™ Human MZB1 Knockdown Stable Cell Line - CSC-DC010060 from Creative biogene Category Cell Line Species Human

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