MZB1

Gene Symbol	MZB1
Entrez Gene	51237
Alt Symbol	MEDA-7, PACAP, pERp1
Species	Human
Gene Type	protein-coding
Description	marginal zone B and B1 cell-specific protein
Other Description	HSPC190|caspase-2 binding protein|marginal zone B- and B1-cell-specific protein|mesenteric estrogen-dependent adipose 7|mesenteric oestrogen-dependent adipose gene- 7|plasma cell-induced ER protein 1|plasma cell-induced resident ER protein|plasma cell-induced resident endoplasmic reticulum protein|proapoptotic caspase adapter protein|proapoptotic caspase adaptor protein
Swissprots	Q9P0T3 Q96RL5 Q7Z6N2 Q8WU39 D2IYS0
Accessions	Q8WU39 AA837360 AF151024 AAF36110 AF338109 AAK84085 AK057549 BAG51934 AK292706 BAF85395 BC009931 AAH09931 BC021275 AAH21275 BU601458 DQ892627 ABM83553 EU176703 ABW03504 GQ477350 ACY74343 NM_016459 NP_057543
Function	Associates with immunoglobulin M (IgM) heavy and light chains and promotes IgM assembly and secretion. May exert its effect by acting as a molecular chaperone or as an oxidoreductase as it displays a low level of oxidoreductase activity (By similarity). Isoform 2 may be involved in regulation of apoptosis. Helps to diversify peripheral B-cell functions by regulating Ca(2+) stores, antibody secretion and integrin activation. {ECO:0000250}.
Subcellular Location	Isoform 1: Endoplasmic reticulum lumen {ECO:0000255|PROSITE-ProRule:PRU10138}. Secreted.
Tissue Specificity	Widely expressed with highest levels in adult brain, small intestine and lymphoid tissues such as thymus and spleen. Expression is frequently lower in intestinal-type gastric cancer. In obese patients, more abundant in omental than in subcutaneous fat. {ECO:0000269|PubMed:11350957, ECO:0000269|PubMed:12792799, ECO:0000269|PubMed:19805157}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human PACAP full length protein - ab157854 from Abcam Category Protein Source Wheat germ Species Human

Human PACAP protein fragment - ab157855 from Abcam Category Protein Source Wheat germ Species Human

Human Proapoptotic Caspase Adaptor Protein full length protein - ab162468 from Abcam Category Protein Source Wheat germ Species Human

Human Proapoptotic Caspase Adaptor Protein full length protein - ab180267 from Abcam Category Protein Source E. coli Species Human

PACAP Antibody Blocking Peptide - LS-E7923 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PACAP Antibody Blocking Peptide - LS-E27093 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Proapoptotic Caspase Adaptor Protein Recombinant Protein - H00051237-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Human MZB1 protein (His Tag) - orb139363 from Biorbyt Category Protein Prices $323.00, $646.00 Sizes 20 μg, 100 μg Source Human Cells Species Human

Human PERP1 (Fc Tag) protein - orb232387 from Biorbyt Category Protein Prices $323.00, $646.00 Sizes 20 μg, 100 μg Species Human

PACAP (6-38) peptide - orb73091 from Biorbyt Category Peptide Prices $340.00 Sizes 500 µg

PACAP (1-38) peptide - orb104223 from Biorbyt Category Peptide Prices $1,054.00 Sizes 1 mg Species Human

PACAP peptide - orb73089 from Biorbyt Category Peptide Prices $238.00 Sizes 500 µg

MZB1 protein (His tag) - 80R-3765 from Fitzgerald Category Protein Prices $275.00 Sizes 100 µg Source E.coli

PACAP (1-27) Peptide - abx064668 from Abbexa Category Peptide Source Human, Sheep, Rat Species Human, Sheep, Rat

PACAP (1-38) Peptide - abx064669 from Abbexa Category Peptide Source Human, Sheep, Rat Species Human, Sheep, Rat

PACAP (6-27) Peptide - abx064670 from Abbexa Category Peptide Source Human, Sheep, Rat Species Human, Sheep, Rat

PACAP (6-38) Peptide - abx064671 from Abbexa Category Peptide Source Human, Sheep, Rat Species Human, Sheep, Rat

PACAP (1-97, His-tag) - AR51452PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

PACAP (1-97, His-tag) - AR51452PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

PACAP - H00051237-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

PACAP - H00051237-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

MZB1, 1-97aa, Human, His tag, E.coli - 01-P2632 from ARP American Research Products Category Protein Prices $179.00, $369.00, $849.00 Sizes 20 µg, 100 µg, 500 µg Species Human

MZB1 fusion protein - ag17912 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

MZB1 fusion protein - Ag2015 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

PACAP (1-38), human, ovine, rat - 52290 from NeoScientific Category Peptide Prices $211.00, $372.00 Sizes 1 mg, 2.5 mg Species Human

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