LRP5

Gene Symbol	LRP5
Entrez Gene	4041
Alt Symbol	BMND1, EVR1, EVR4, HBM, LR3, LRP-5, LRP7, OPPG, OPS, OPTA1, VBCH2
Species	Human
Gene Type	protein-coding
Description	low density lipoprotein receptor-related protein 5
Other Description	low density lipoprotein receptor-related protein 7|low-density lipoprotein receptor-related protein 5
Swissprots	Q9UES7 Q9UP66 Q96TD6 O75197
Accessions	AAK52433 EAW74705 EAW74706 O75197 AA279383 AA953315 AB017498 BAA33051 AF064548 AAC36467 AF077820 AAC72791 AF088027 AI583742 BC098397 BC150595 AAI50596 DN999254 XM_005273994 XP_005274051 XM_011545029 XP_011543331 XM_011545030 XP_011543332 XM_011545031 XP_011543333 XR_949925 XR_949926 NM_001291902 NP_001278831 NM_002335 NP_002326
Function	Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor- ligand complexes into ribosome-sized signalsomes. Cell-surface coreceptor of Wnt/beta-catenin signaling, which plays a pivotal role in bone formation. The Wnt-induced Fzd/LRP6 coreceptor complex recruits DVL1 polymers to the plasma membrane which, in turn, recruits the AXIN1/GSK3B-complex to the cell surface promoting the formation of signalsomes and inhibiting AXIN1/GSK3- mediated phosphorylation and destruction of beta-catenin. Appears be required for postnatal control of vascular regression in the eye. Required for posterior patterning of the epiblast during gastrulation. {ECO:0000269|PubMed:11336703, ECO:0000269|PubMed:11448771, ECO:0000269|PubMed:14727154, ECO:0000269|PubMed:14731402, ECO:0000269|PubMed:15778503}.
Subcellular Location	Membrane; Single-pass type I membrane protein. Endoplasmic reticulum {ECO:0000250}. Note=Chaperoned to the plasma membrane by MESD. {ECO:0000250}.
Tissue Specificity	Widely expressed, with the highest level of expression in the liver and in aorta. {ECO:0000269|PubMed:9790987}.
Top Pathways	Wnt signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Rat LRP5 ELISA Kit (Sandwich ELISA) - LS-F8902 from LifeSpan Bioscience Category ELISA Kit Prices $780.00 Sizes 1 plate Sensitivity 0.3 ng/ml Range 0.781-50 ng/ml

Human LRP5 ELISA Kit (Sandwich ELISA) - LS-F11980 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 0.312 Range 0.781-50 ng/ml

Low-density lipoprotein receptor-related protein 5, LRP5, Human, ELISA Kit - E3681h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 0.312-20 ng/mL

Low-density lipoprotein-receptor-related protein 5, LRP-5, Human, ELISA Kit - CSB-E13502h from ARP American Research Products Category ELISA Kit Prices $550.00, $790.00, $791.00, $794.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Low Density Lipoprotein Receptor Related Protein 5, ELISA Kit - MBS068352 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Low Density Lipoprotein Receptor Related Protein 5, ELISA Kit - MBS078343 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Low Density Lipoprotein Receptor Related Protein 5, ELISA Kit - MBS082981 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Low Density Lipoprotein Receptor Related Protein 5, ELISA Kit - MBS053797 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Low Density Lipoprotein Receptor Related Protein 5, ELISA Kit - MBS096306 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Low Density Lipoprotein Receptor Related Protein 5, ELISA Kit - MBS071987 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Low Density Lipoprotein Receptor Related Protein 5, ELISA Kit - MBS051775 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Low Density Lipoprotein Receptor Related Protein 5, ELISA Kit - MBS069704 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Low Density Lipoprotein Receptor Related Protein 5, ELISA Kit - MBS093262 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Low Density Lipoprotein Receptor Related Protein 5, ELISA Kit - MBS073048 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Low Density Lipoprotein Receptor Related Protein 5, ELISA Kit - MBS084360 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Low Density Lipoprotein Receptor Related Protein 5, ELISA Kit - MBS099215 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Low Density Lipoprotein Receptor Related Protein 5, ELISA Kit - MBS079257 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Low Density Lipoprotein Receptor Related Protein 5, ELISA Kit - MBS051353 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Low Density Lipoprotein Receptor Related Protein 5, ELISA Kit - MBS067995 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Low Density Lipoprotein Receptor Related Protein 5, ELISA Kit - MBS078502 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Low Density Lipoprotein Receptor Related Protein 5, ELISA Kit - MBS078774 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Low Density Lipoprotein Receptor Related Protein 5, ELISA Kit - MBS103108 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Low Density Lipoprotein Receptor Related Protein 5, ELISA Kit - MBS097490 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Low Density Lipoprotein Receptor Related Protein 5, ELISA Kit - MBS057307 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Low Density Lipoprotein Receptor Related Protein 5, ELISA Kit - MBS091632 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Search more