PGF

Gene Symbol PGF
Entrez Gene 5228
Alt Symbol D12S1900, PGFL, PLGF, PlGF-2, SHGC-10760
Species Human
Gene Type protein-coding
Description placental growth factor
Other Description placenta growth factor|placental growth factor, vascular endothelial growth factor-related protein
Swissprots Q9Y6S8 Q9BV78 Q07101 P49763
Accessions AAB25832 AAD30179 ABY87550 AGC09600 CAH23419 CAI84580 CAJ32891 CAL32761 CBH30536 EAW81207 EAW81208 EAW81209 P49763 A18411 CAA01393 AK023843 AK309886 AK310608 AK310886 AL543693 BC001422 AAH01422 BC007255 AAH07255 BC007789 AAH07789 BT007182 AAP35846 BX248289 CAD62617 BX356823 DQ892136 ABM83062 DQ895330 ABM86256 S72960 AAB30462 X54936 CAA38698 NM_001207012 NP_001193941 NM_001293643 NP_001280572 NM_002632 NP_002623
Function Growth factor active in angiogenesis and endothelial cell growth, stimulating their proliferation and migration. It binds to the receptor FLT1/VEGFR-1. Isoform PlGF-2 binds NRP1/neuropilin-1 and NRP2/neuropilin-2 in a heparin-dependent manner. Also promotes cell tumor growth. {ECO:0000269|PubMed:21215706}.
Subcellular Location Secreted. Note=The three isoforms are secreted but PlGF-2 appears to remain cell attached unless released by heparin.
Tissue Specificity While the three isoforms are present in most placental tissues, PlGF-2 is specific to early (8 week) placenta and only PlGF-1 is found in the colon and mammary carcinomas.
Top Pathways Focal adhesion, PI3K-Akt signaling pathway, Rap1 signaling pathway

PlGF (C-20) - sc-1880 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
PlGF (C-20): sc-1880. Western blot analysis of human (A) and mouse (B) recombinant PlGF.

PlGF (H-90) - sc-20714 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

PlGF (L-20) - sc-27133 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

PlGF (P-19) - sc-27132 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

PlGF (MM0010-2D93) - sc-101572 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal

PlGF (37203.111) - sc-57402 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal

Anti-PLGF antibody - ab9542 from Abcam

Prices $385.00
Sizes 200 µg
Host Rabbit
Clonality Polyclonal
Western blot of chromatography purified, recombinant PlGF-1/-2 and VEGF165 immobilized to PVDF-membrane. PlGF antibody shows no cross-reactivity to VEGF165.

Anti-PLGF antibody - ab196666 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-PLGF antibody (ab196666) at 1/500 dilutionLane 1 : BT474 cell extractLane 2 : Mouse brain tissue extract

Anti-PLGF antibody - ab11938 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-PLGF antibody (ab11938)Lane 1 : Recombinant human PLGFLane 2 : Recombinant mouse PLGF

Anti-PLGF antibody - ab99250 from Abcam

Prices $376.00
Sizes 200 µl
Host Goat
Clonality Polyclonal
Anti-PLGF antibody (ab99250) at 1 µg/ml + Human Placenta lysate (in RIPA buffer) at 35 µgdeveloped using the ECL technique

Anti-PLGF antibody [37203.111] - ab10966 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 37203.111

Anti-PLGF antibody [EPR2802(2)] - ab140639 from Abcam

Prices $379.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR2802(2)
Anti-PLGF antibody [EPR2802(2)] (ab140639) at 1/1000 dilution + JAR cell lysate at 10 µg

Anti-PLGF antibody [PLGF94] - ab190717 from Abcam

Prices $368.00
Sizes 500 µl
Host Mouse
Clonality Monoclonal
Clone PLGF94

Anti-PLGF antibody - C-terminal - ab176391 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-PLGF antibody - C-terminal (ab176391) at 0.5 µg/ml + Human Placenta Tissue Lysate

Anti-PLGF1 antibody - ab180734 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of rat testis tissue labelling PLGF1 with ab180734 at 1/200. Magnification: 400x.

Anti-PGF / PLGF Antibody (N-Terminus) - LS-C17318 from LifeSpan Bioscience

Prices $530.00
Sizes 200 µg
Host Rabbit
Clonality Polyclonal

Anti-PGF / PLGF Antibody - LS-C48952 from LifeSpan Bioscience

Prices $445.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PGF / PLGF Antibody - LS-C91984 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-PGF / PLGF Antibody - LS-C56848 from LifeSpan Bioscience

Prices $435.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PGF / PLGF Antibody (N-Terminus) - LS-C122322 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PGF / PLGF Antibody (Biotin) - LS-C104525 from LifeSpan Bioscience

Prices $285.00, $325.00
Sizes 25 µg, 50 µg
Host Rabbit
Clonality Polyclonal

Anti-PGF / PLGF Antibody (N-Terminus, Sepharose) - LS-C171825 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PGF / PLGF Antibody (N-Terminus, Magnetic beads) - LS-C171824 from LifeSpan Bioscience

Prices $325.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PGF / PLGF Antibody (Biotin) - LS-C190402 from LifeSpan Bioscience

Prices $590.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-PGF / PLGF Antibody (aa91-141) - LS-C191200 from LifeSpan Bioscience

Prices $725.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
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