PGF

Gene Symbol	PGF
Entrez Gene	5228
Alt Symbol	D12S1900, PGFL, PLGF, PlGF-2, SHGC-10760
Species	Human
Gene Type	protein-coding
Description	placental growth factor
Other Description	placenta growth factor|placental growth factor, vascular endothelial growth factor-related protein
Swissprots	Q9Y6S8 Q9BV78 Q07101 P49763
Accessions	AAB25832 AAD30179 ABY87550 AGC09600 CAH23419 CAI84580 CAJ32891 CAL32761 CBH30536 EAW81207 EAW81208 EAW81209 P49763 A18411 CAA01393 AK023843 AK309886 AK310608 AK310886 AL543693 BC001422 AAH01422 BC007255 AAH07255 BC007789 AAH07789 BT007182 AAP35846 BX248289 CAD62617 BX356823 DQ892136 ABM83062 DQ895330 ABM86256 S72960 AAB30462 X54936 CAA38698 NM_001207012 NP_001193941 NM_001293643 NP_001280572 NM_002632 NP_002623
Function	Growth factor active in angiogenesis and endothelial cell growth, stimulating their proliferation and migration. It binds to the receptor FLT1/VEGFR-1. Isoform PlGF-2 binds NRP1/neuropilin-1 and NRP2/neuropilin-2 in a heparin-dependent manner. Also promotes cell tumor growth. {ECO:0000269|PubMed:21215706}.
Subcellular Location	Secreted. Note=The three isoforms are secreted but PlGF-2 appears to remain cell attached unless released by heparin.
Tissue Specificity	While the three isoforms are present in most placental tissues, PlGF-2 is specific to early (8 week) placenta and only PlGF-1 is found in the colon and mammary carcinomas.
Top Pathways	Focal adhesion, PI3K-Akt signaling pathway, Rap1 signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

PLGF Human ELISA Kit - ab100629 from Abcam Category ELISA Kit Prices $489.00 Sizes 1 x 96 tests Sensitivity < 2 pg/ml Range 1.372 pg/ml - 1000 pg/ml

Human PGF / PLGF ELISA Kit (Sandwich ELISA) - LS-F5171 from LifeSpan Bioscience Category ELISA Kit Prices $490.00 Sizes 1 plate Sensitivity 25.8 pg/ml Range 1.371-1000 pg/ml

Rat PGF / PLGF ELISA Kit (Sandwich ELISA) - LS-F5506 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity 2.7 pg/ml Range 1.371-1000 pg/ml

Mouse PGF / PLGF ELISA Kit (Sandwich ELISA) - LS-F5507 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate Sensitivity 12.1 pg/ml Range 1.371-1000 pg/ml

Human PGF / PLGF ELISA Kit (Sandwich ELISA) - LS-F2536 from LifeSpan Bioscience Category ELISA Kit Prices $550.00 Sizes 1 plate Sensitivity 1 pg/ml Range 1.371-1000 pg/ml

Human PGF / PLGF ELISA Kit (Sandwich ELISA) - LS-F594 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate Range 1.371-1000 pg/ml

Human PGF / PLGF ELISA Kit (Sandwich ELISA) - LS-F177 from LifeSpan Bioscience Category ELISA Kit Prices $460.00, $840.00, $1,960.00 Sizes 1 plate, 2 plate, 5 plate Sensitivity 1.371 pg/ml Range 1.371-1000 pg/ml

Human PGF / PLGF ELISA Kit (Sandwich ELISA) - LS-F12346 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 31.2 Range 1.371-1000 pg/ml

Human Placental Growth Factor  ELISA Kit - RAB0404 from Sigma-Aldrich Category ELISA Kit Prices $423.50 Sizes 1 kt

Human PlGF Luminex Performance Assay - LAN264 from R&D Systems

Human PlGF Magnetic Luminex Performance Assay - LANM264 from R&D Systems

Human PlGF Quantikine ELISA Kit - DPG00 from R&D Systems Category ELISA Kit Prices $519.00, $2,491.00, $16,868.00 Sizes 1 kit, 1 pack (6 Plates), 1 pack (50 Plates) Sensitivity 7 pg/mL Range 15.6 - 1,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Citrate Plasma, Urine)

Human PlGF Quantikine PharmPak (50 Plates) - PDPG00 from R&D Systems Category ELISA Kit Sensitivity 7 pg/mL Range 15.6 - 1,000 pg/mL (Serum, Heparin Plasma, Cell Culture Supernates, Citrate Plasma, EDTA Plasma, Urine)

Human PlGF Quantikine SixPak (6 Plates) - SPG00 from R&D Systems Category ELISA Kit Sensitivity 7 pg/mL Range 15.6 - 1,000 pg/mL (Serum, Heparin Plasma, Cell Culture Supernates, Citrate Plasma, EDTA Plasma, Urine)

Mouse PlGF-2 Quantikine ELISA Kit - MP200 from R&D Systems Category ELISA Kit Prices $479.00 Sizes 1 kit Sensitivity 1.84 pg/mL Range 23.4 - 1,500 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma)

Human PlGF DuoSet ELISA - DY264 from R&D Systems Category ELISA Kit Prices $649.00 Sizes 1 kit (for 15 Plates) Range 31.20 - 2,000 pg/mL

Mouse PlGF-2 DuoSet ELISA - DY465 from R&D Systems Category ELISA Kit Prices $649.00 Sizes 1 kit (for 15 Plates) Range 15.60 - 1,000 pg/mL

Human PlGF Quantikine HS ELISA Kit - HSPG00 from R&D Systems Category ELISA Kit Prices $599.00 Sizes 1 kit Sensitivity 0.326 pg/mL Range 3.1 - 200 pg/mL (Serum, EDTA Plasma, Heparin Plasma)

Quantikine Immunoassay Control Set 813 for Human HS PlGF - QC144 from R&D Systems Category ELISA Kit Prices $125.00 Sizes 1 each

Human Placental Growth Factor ELISA Kit - 55R-1671 from Fitzgerald Category ELISA Kit Prices $425.00 Sizes 1 kit

PLGF ELISA Kit (Human) : 96 Wells (OKAG00057) - OKAG00057 from Aviva Systems Biology Category ELISA Kit Prices $390.00 Sizes 96 wells Sensitivity 32 pg/mL Range 32-2,000 pg/mL

Human Placenta Growth Factor ELISA Kit - abx053186 from Abbexa Category ELISA Kit

Human PLGF ELISA kit - abx050192 from Abbexa Category ELISA Kit Sensitivity < 1pg/ml Range 15.6 pg/ml-1000 pg/ml

Human PLGF ELISA Kit - abx152780 from Abbexa Category ELISA Kit Sensitivity 6.3 pg/ml Range 15.625 pg/ml - 1000 pg/ml

Human PLGF ELISA Kit - abx056310 from Abbexa Category ELISA Kit

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