PGF

Gene Symbol PGF
Entrez Gene 5228
Alt Symbol D12S1900, PGFL, PLGF, PlGF-2, SHGC-10760
Species Human
Gene Type protein-coding
Description placental growth factor
Other Description placenta growth factor|placental growth factor, vascular endothelial growth factor-related protein
Swissprots Q9Y6S8 Q9BV78 Q07101 P49763
Accessions AAB25832 AAD30179 ABY87550 AGC09600 CAH23419 CAI84580 CAJ32891 CAL32761 CBH30536 EAW81207 EAW81208 EAW81209 P49763 A18411 CAA01393 AK023843 AK309886 AK310608 AK310886 AL543693 BC001422 AAH01422 BC007255 AAH07255 BC007789 AAH07789 BT007182 AAP35846 BX248289 CAD62617 BX356823 DQ892136 ABM83062 DQ895330 ABM86256 S72960 AAB30462 X54936 CAA38698 NM_001207012 NP_001193941 NM_001293643 NP_001280572 NM_002632 NP_002623
Function Growth factor active in angiogenesis and endothelial cell growth, stimulating their proliferation and migration. It binds to the receptor FLT1/VEGFR-1. Isoform PlGF-2 binds NRP1/neuropilin-1 and NRP2/neuropilin-2 in a heparin-dependent manner. Also promotes cell tumor growth. {ECO:0000269|PubMed:21215706}.
Subcellular Location Secreted. Note=The three isoforms are secreted but PlGF-2 appears to remain cell attached unless released by heparin.
Tissue Specificity While the three isoforms are present in most placental tissues, PlGF-2 is specific to early (8 week) placenta and only PlGF-1 is found in the colon and mammary carcinomas.
Top Pathways Focal adhesion, PI3K-Akt signaling pathway, Rap1 signaling pathway

PlGF CRISPR/Cas9 KO Plasmid (h) - sc-402864 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PlGF HDR Plasmid (h) - sc-402864-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PlGF Double Nickase Plasmid (h) - sc-402864-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PlGF Double Nickase Plasmid (h2) - sc-402864-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PlGF CRISPR Activation Plasmid (h) - sc-402864-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PlGF CRISPR Activation Plasmid (h2) - sc-402864-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PlGF Lentiviral Activation Particles (h) - sc-402864-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PlGF Lentiviral Activation Particles (h2) - sc-402864-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PlGF siRNA (h) - sc-44027 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PlGF shRNA Plasmid (h) - sc-44027-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PlGF shRNA (h) Lentiviral Particles - sc-44027-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU064891 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN16683 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16683 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

PGF siRNA (Human) - CRH3493 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human PGF (NM_002632.5) - SHH374224 from Creative biogene

Category siRNA
Species Reactivities Human

Human PGF siRNA - orb263995 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

PGF shRNA Plasmid (Human) - CHH3493 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

PGF miRNA 3'UTR clone - MiUTR3H-03892 from Creative biogene

Species Reactivities Human
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