PGF

Gene Symbol	PGF
Entrez Gene	5228
Alt Symbol	D12S1900, PGFL, PLGF, PlGF-2, SHGC-10760
Species	Human
Gene Type	protein-coding
Description	placental growth factor
Other Description	placenta growth factor|placental growth factor, vascular endothelial growth factor-related protein
Swissprots	Q9Y6S8 Q9BV78 Q07101 P49763
Accessions	AAB25832 AAD30179 ABY87550 AGC09600 CAH23419 CAI84580 CAJ32891 CAL32761 CBH30536 EAW81207 EAW81208 EAW81209 P49763 A18411 CAA01393 AK023843 AK309886 AK310608 AK310886 AL543693 BC001422 AAH01422 BC007255 AAH07255 BC007789 AAH07789 BT007182 AAP35846 BX248289 CAD62617 BX356823 DQ892136 ABM83062 DQ895330 ABM86256 S72960 AAB30462 X54936 CAA38698 NM_001207012 NP_001193941 NM_001293643 NP_001280572 NM_002632 NP_002623
Function	Growth factor active in angiogenesis and endothelial cell growth, stimulating their proliferation and migration. It binds to the receptor FLT1/VEGFR-1. Isoform PlGF-2 binds NRP1/neuropilin-1 and NRP2/neuropilin-2 in a heparin-dependent manner. Also promotes cell tumor growth. {ECO:0000269|PubMed:21215706}.
Subcellular Location	Secreted. Note=The three isoforms are secreted but PlGF-2 appears to remain cell attached unless released by heparin.
Tissue Specificity	While the three isoforms are present in most placental tissues, PlGF-2 is specific to early (8 week) placenta and only PlGF-1 is found in the colon and mammary carcinomas.
Top Pathways	Focal adhesion, PI3K-Akt signaling pathway, Rap1 signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human PGF gene - orb90864 from Biorbyt Prices $255.00 Sizes 10 μg Species Human

Human-PGF-cDNA-Clone - DC00666 from Abgent, a WuXi AppTec company Prices $229.50 Sizes 10 µg Species Human Accession BC001422

PGF - MBS1267074 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC001422

Human PGF Gene ORF cDNA clone in cloning vector - HG10274-M from Sino Biological Species Human

Human PGF Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG10274-ACR from Sino Biological Species Human

Human PGF Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG10274-ACG from Sino Biological Species Human

Human PGF / PLGF Gene cDNA Clone (full-length ORF Clone), expression ready, N-His-tagged - HG10274-NH from Sino Biological Species Human Accession NM_002632.4

Human PGF Gene ORF cDNA clone expression plasmid - HG10274-UT from Sino Biological Species Human

Human PGF Gene ORF cDNA clone expression plasmid, C-HA tag - HG10274-CY from Sino Biological Species Human

Human PGF / PLGF Gene cDNA Clone (full-length ORF Clone) expression ready, untagged - HG10274-M-N from Sino Biological Species Human Accession NM_002632.4

Human PGF / PLGF Gene cDNA Clone (full-length ORF Clone) expression ready, FLAG-tagged - HG10274-M-F from Sino Biological Species Human Accession NM_002632.4

Human PGF Gene ORF cDNA clone expression plasmid, N-Flag tag - HG10274-NF from Sino Biological Species Human

Human PGF Gene ORF cDNA clone expression plasmid, C-Flag tag - HG10274-CF from Sino Biological Species Human

Human PGF Gene ORF cDNA clone expression plasmid, N-Myc tag - HG10274-NM from Sino Biological Species Human

Human PGF Gene ORF cDNA clone expression plasmid, C-His tag - HG10274-CH from Sino Biological Species Human

Human PGF Gene ORF cDNA clone expression plasmid, N-HA tag - HG10274-NY from Sino Biological Species Human

Human PGF Gene ORF cDNA clone expression plasmid, C-Myc tag - HG10274-CM from Sino Biological Species Human

Human PGF ORF clone (NM_001207012.1) - CDCL148431 from Creative biogene Species Human

Human PGF ORF Clone (BC001422) - CDCS409694 from Creative biogene Species Human Accession P49763

Human PGF ORF clone (NM_002632.4) - CDCB157555 from Creative biogene Species Human

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