TNFRSF1A

Gene Symbol	TNFRSF1A
Entrez Gene	7132
Alt Symbol	CD120a, FPF, MS5, TBP1, TNF-R, TNF-R-I, TNF-R55, TNFAR, TNFR1, TNFR1-d2, TNFR55, TNFR60, p55, p55-R, p60
Species	Human
Gene Type	protein-coding
Description	tumor necrosis factor receptor superfamily, member 1A
Other Description	TNF-R1|TNF-RI|TNFR-I|tumor necrosis factor binding protein 1|tumor necrosis factor receptor 1A isoform beta|tumor necrosis factor receptor superfamily member 1A|tumor necrosis factor receptor type 1|tumor necrosis factor-alpha receptor
Swissprots	D3DUR1 B4DQB7 B4E309 P19438 B2RDE4 B3KPQ1 B5M0B5 Q9UCA4 A8K4X3
Accessions	AAA61201 AAM77802 CAI84622 CCA94574 EAW88805 EAW88806 P19438 A21522 CAA01558 AK056611 BAG51763 AK130807 AK291088 BAF83777 AK298729 BAG60879 AK304517 BAG65321 AK308061 AK315509 BAG37891 AY182755 AAO23979 BC010140 AAH10140 BF528949 DA664652 EU176385 ABW03836 EU176726 ABW03527 EU927389 ACH57451 JN172914 AEO89726 M33294 AAA03210 M58286 AAA36753 M60275 AAA36756 M63121 AAA36754 NM_001065 NP_001056
Function	Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate- specific cysteine proteases) mediating apoptosis. Contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase.
Subcellular Location	Cell membrane {ECO:0000269|PubMed:22801493}; Single-pass type I membrane protein {ECO:0000269|PubMed:22801493}. Golgi apparatus membrane {ECO:0000269|PubMed:22801493}; Single- pass type I membrane protein {ECO:0000269|PubMed:22801493}. Secreted {ECO:0000269|PubMed:22801493}. Note=A secreted form is produced through proteolytic processing.
Top Pathways	Sphingolipid signaling pathway, Herpes simplex infection, TNF signaling pathway, Non-alcoholic fatty liver disease (NAFLD), Tuberculosis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Soluble TNF Receptor I Human ELISA Kit - ab100642 from Abcam Category ELISA Kit Prices $489.00 Sizes 1 x 96 tests Sensitivity < 1 pg/ml Range 0.55 pg/ml - 400 pg/ml

Human soluble TNF Receptor 1 ELISA Kit - RAB0489 from Sigma-Aldrich Category ELISA Kit Prices $423.50 Sizes 1 kt

Human TNFRSF1A / TNFR1 ELISA Kit (Sandwich ELISA) - LS-F1029 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate Range 13-800 pg/ml

Rat TNFRSF1A / TNFR1 ELISA Kit (Sandwich ELISA) - LS-F8072 from LifeSpan Bioscience Category ELISA Kit Prices $740.00 Sizes 1 plate Sensitivity 0.055 ng/ml Range 13-800 pg/ml

Human TNFRSF1A / TNFR1 ELISA Kit (Sandwich ELISA) - LS-F8739 from LifeSpan Bioscience Category ELISA Kit Prices $470.00 Sizes 1 plate Sensitivity 6.5 pg/ml Range 13-800 pg/ml

Mouse TNFRSF1A / TNFR1 ELISA Kit (Sandwich ELISA) - LS-F9991 from LifeSpan Bioscience Category ELISA Kit Prices $630.00 Sizes 1 plate Sensitivity 1.261 pg/ml Range 13-800 pg/ml

Human TNFRSF1A / TNFR1 ELISA Kit (Sandwich ELISA) - LS-F10269 from LifeSpan Bioscience Category ELISA Kit Prices $610.00 Sizes 1 plate Sensitivity 65 pg/ml Range 13-800 pg/ml

Human TNFRSF1A / TNFR1 ELISA Kit (Sandwich ELISA) - LS-F2560 from LifeSpan Bioscience Category ELISA Kit Prices $570.00 Sizes 1 plate Sensitivity 1 pg/ml Range 13-800 pg/ml

Pig TNFRSF1A / TNFR1 ELISA Kit (Sandwich ELISA) - LS-F12819 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity 15.6 Range 13-800 pg/ml

Bovine TNFRSF1A / TNFR1 ELISA Kit (Sandwich ELISA) - LS-F12820 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity 62.5 Range 13-800 pg/ml

Human sTNF RI/TNFRSF1A Quantikine ELISA Kit - DRT100 from R&D Systems Category ELISA Kit Prices $509.00, $2,440.00, $16,540.00 Sizes 1 kit, 1 pack (6 Plates), 1 pack (50 Plates) Sensitivity 1.2 pg/mL Range 7.8 - 500 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Citrate Plasma, Urine)

Human sTNF RI/TNFRSF1A Quantikine PharmPak (50 Plates) - PDRT100 from R&D Systems Category ELISA Kit Sensitivity 1.2 pg/mL Range 7.8 - 500 pg/mL (Serum, Heparin Plasma, Cell Culture Supernates, Citrate Plasma, EDTA Plasma, Urine)

Human sTNF RI/TNFRSF1A Quantikine SixPak (6 Plates) - SRT100 from R&D Systems Category ELISA Kit Sensitivity 1.2 pg/mL Range 7.8 - 500 pg/mL (Serum, Heparin Plasma, Cell Culture Supernates, Citrate Plasma, EDTA Plasma, Urine)

Mouse/Rat TNF RI/TNFRSF1A Quantikine ELISA Kit - MRT10 from R&D Systems Category ELISA Kit Prices $479.00 Sizes 1 kit Sensitivity 2.4 pg/mL Range 15.6 - 1,000 pg/mL (Cell Culture Supernates, Serum)

Human TNF RI/TNFRSF1A DuoSet ELISA - DY225 from R&D Systems Category ELISA Kit Prices $249.00, $649.00 Sizes 1 kit (for 5 Plates), 1 kit (for 15 Plates) Range 12.50 - 800 pg/mL

Mouse TNF RI/TNFRSF1A DuoSet ELISA - DY425 from R&D Systems Category ELISA Kit Prices $649.00 Sizes 1 kit (for 15 Plates) Range 7.81 - 500 pg/mL

Human TNF RI/TNFRSF1A DuoSet, 5 Plate - DY225-05 from R&D Systems Category ELISA Kit

Human TNFR1 ELISA Kit - 55R-1693 from Fitzgerald Category ELISA Kit Prices $440.00 Sizes 1 kit

Monkey TNFR1 ELISA kit - 55R-IB49727 from Fitzgerald Category ELISA Kit Prices $745.00 Sizes 96 wells

TNFR1 ELISA kit - 55R-2252 from Fitzgerald Category ELISA Kit Prices $695.00 Sizes 1 kit

sTNF-R1 ELISA Kit (Human) : 96 Wells (OKAG00249) - OKAG00249 from Aviva Systems Biology Category ELISA Kit Prices $390.00 Sizes 96 wells Sensitivity 13 pg/mL Range 13-800 pg/mL

Human CD120a ELISA Kit - abx056057 from Abbexa Category ELISA Kit

sTNFR1, Human, ELISA Kit - BEK1216 from ARP American Research Products Category ELISA Kit Prices $529.00 Sizes 96 t Sensitivity < 1pg/ml Range 7.8 pg/ml-500 pg/ml

Tumor Necrosis Factor Receptor Superfamily, Member 1A, TNFRSF1A, Human, ELISA Kit - E-EL-H0217 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 4.688 Range 7.813-500pg/mL

Tumor necrosis factor receptor superfamily member 1A, TNFRSF1A, Human, ELISA Kit - E0131h from ARP American Research Products Category ELISA Kit Prices $476.00 Sizes 96 t Range 15.6-1000 pg/mL

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