TNFRSF1A

Gene Symbol	TNFRSF1A
Entrez Gene	7132
Alt Symbol	CD120a, FPF, MS5, TBP1, TNF-R, TNF-R-I, TNF-R55, TNFAR, TNFR1, TNFR1-d2, TNFR55, TNFR60, p55, p55-R, p60
Species	Human
Gene Type	protein-coding
Description	tumor necrosis factor receptor superfamily, member 1A
Other Description	TNF-R1|TNF-RI|TNFR-I|tumor necrosis factor binding protein 1|tumor necrosis factor receptor 1A isoform beta|tumor necrosis factor receptor superfamily member 1A|tumor necrosis factor receptor type 1|tumor necrosis factor-alpha receptor
Swissprots	D3DUR1 B4DQB7 B4E309 P19438 B2RDE4 B3KPQ1 B5M0B5 Q9UCA4 A8K4X3
Accessions	AAA61201 AAM77802 CAI84622 CCA94574 EAW88805 EAW88806 P19438 A21522 CAA01558 AK056611 BAG51763 AK130807 AK291088 BAF83777 AK298729 BAG60879 AK304517 BAG65321 AK308061 AK315509 BAG37891 AY182755 AAO23979 BC010140 AAH10140 BF528949 DA664652 EU176385 ABW03836 EU176726 ABW03527 EU927389 ACH57451 JN172914 AEO89726 M33294 AAA03210 M58286 AAA36753 M60275 AAA36756 M63121 AAA36754 NM_001065 NP_001056
Function	Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate- specific cysteine proteases) mediating apoptosis. Contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase.
Subcellular Location	Cell membrane {ECO:0000269|PubMed:22801493}; Single-pass type I membrane protein {ECO:0000269|PubMed:22801493}. Golgi apparatus membrane {ECO:0000269|PubMed:22801493}; Single- pass type I membrane protein {ECO:0000269|PubMed:22801493}. Secreted {ECO:0000269|PubMed:22801493}. Note=A secreted form is produced through proteolytic processing.
Top Pathways	Sphingolipid signaling pathway, Herpes simplex infection, TNF signaling pathway, Non-alcoholic fatty liver disease (NAFLD), Tuberculosis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human CD120a gene - orb91332 from Biorbyt Prices $255.00 Sizes 10 μg Species Human

Rat TNF RI/TNFRSF1A (NP_037223) VersaClone cDNA - RDC0363 from R&D Systems Prices $199.00 Sizes 10 µg Species Rat

TNFRSF1A - MBS1275778 from MyBioSource Species Human Accession BC010140

Human TNFRSF1A ORF Clone(NM_001065.3) - CDCL179224 from Creative Biomart Species Human Accession NM_001065.3

human TNFRSF1A ORF clone - CDCH093518 from Creative Biomart Species Human Accession NM_001065

human TNFRSF1A ORF clone - CDCH093519 from Creative Biomart Species Human Accession NM_001065

human TNFRSF1A ORF clone - CDCH093520 from Creative Biomart Species Human Accession NM_001065

human TNFRSF1A ORF clone - CDCH093521 from Creative Biomart Species Human Accession NM_001065

Human TNFR1/TNFRSF1A/CD120a Gene ORF cDNA clone in cloning vector - HG10872-M from Sino Biological Species Human

Human TNFR1/TNFRSF1A/CD120a Gene ORF cDNA clone expression plasmid, C-Myc tag - HG10872-CM from Sino Biological Species Human

Human TNFR1/TNFRSF1A/CD120a Gene ORF cDNA clone expression plasmid, C-Flag tag - HG10872-M-F from Sino Biological Species Human

Human TNFR1/TNFRSF1A/CD120a Gene ORF cDNA clone expression plasmid - HG10872-M-N from Sino Biological Species Human

Human TNFR1/TNFRSF1A/CD120a Gene ORF cDNA clone expression plasmid, N-His tag - HG10872-NH from Sino Biological Species Human

Human TNFR1/TNFRSF1A/CD120a Gene ORF cDNA clone expression plasmid, N-HA tag - HG10872-NY from Sino Biological Species Human

Human TNFR1/TNFRSF1A/CD120a Gene ORF cDNA clone expression plasmid, C-His tag - HG10872-CH from Sino Biological Species Human

Human TNFR1/TNFRSF1A/CD120a Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG10872-ACR from Sino Biological Species Human

Human TNFR1/TNFRSF1A/CD120a Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG10872-ACG from Sino Biological Species Human

Human TNFR1/TNFRSF1A/CD120a Gene ORF cDNA clone expression plasmid - HG10872-UT from Sino Biological Species Human

Human TNFR1/TNFRSF1A/CD120a Gene ORF cDNA clone expression plasmid, N-Flag tag - HG10872-NF from Sino Biological Species Human

Human TNFR1/TNFRSF1A/CD120a Gene ORF cDNA clone expression plasmid, N-Myc tag - HG10872-NM from Sino Biological Species Human

Human TNFR1/TNFRSF1A/CD120a Gene ORF cDNA clone expression plasmid, C-HA tag - HG10872-CY from Sino Biological Species Human

Human TNFR1/TNFRSF1A/CD120a Gene ORF cDNA clone expression plasmid, C-Flag tag - HG10872-CF from Sino Biological Species Human

Mouse TNF RI/TNFRSF1A (NP_035739) VersaClone cDNA - RDC1526 from R&D Systems Prices $199.00 Sizes 10 µg Species Mouse

Human TNFRSF1A ORF Clone (BC010140) - CDCS407176 from Creative biogene Species Human Accession P19438

Cyno Monkey TNF RI/TNFRSF1A (NP_001306550) VersaClone cDNA - RDC2200 from R&D Systems Species Monkey

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