SNAI1

Gene Symbol	SNAI1
Entrez Gene	6615
Alt Symbol	SLUGH2, SNA, SNAH, SNAIL, SNAIL1, dJ710H13.1
Species	Human
Gene Type	protein-coding
Description	snail family zinc finger 1
Other Description	protein sna|protein snail homolog 1|snail 1 homolog|snail 1 zinc finger protein|snail 1, zinc finger protein|snail homolog 1|zinc finger protein SNAI1
Swissprots	Q9P113 Q9UHH7 B2R842 O95863 Q9UBP7
Accessions	AAD52986 AAD52996 CAB52414 CBX55848 EAW75640 O95863 AF125377 AAD17332 AF131208 AAF32527 AK313228 BAG36039 BC012910 AAH12910 BI822180 DA972913 DQ891599 ABM82525 DQ894793 ABM85719 NM_005985 NP_005976
Function	Involved in induction of the epithelial to mesenchymal transition (EMT), formation and maintenance of embryonic mesoderm, growth arrest, survival and cell migration. Binds to 3 E-boxes of the E-cadherin/CDH1 gene promoter and to the promoters of CLDN7 and KRT8 and, in association with histone demethylase KDM1A which it recruits to the promoters, causes a decrease in dimethylated H3K4 levels and represses transcription. Associates with EGR1 and SP1 to mediate tetradecanoyl phorbol acetate (TPA)-induced up- regulation of CDKN2B, possibly by binding to the CDKN2B promoter region 5'-TCACA-3. In addition, may also activate the CDKN2B promoter by itself. {ECO:0000269|PubMed:10655587, ECO:0000269|PubMed:15647282, ECO:0000269|PubMed:16096638, ECO:0000269|PubMed:20121949, ECO:0000269|PubMed:20562920, ECO:0000269|PubMed:21952048}.
Subcellular Location	Nucleus. Cytoplasm. Note=Once phosphorylated (probably on Ser-107, Ser-111, Ser-115 and Ser-119) it is exported from the nucleus to the cytoplasm where subsequent phosphorylation of the destruction motif and ubiquitination involving BTRC occurs.
Tissue Specificity	Expressed in a variety of tissues with the highest expression in kidney. Expressed in mesenchymal and epithelial cell lines. {ECO:0000269|PubMed:10655587}.
Top Pathways	Adherens junction

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Mouse/Human SNAI1 / SNAIL-1 ELISA Kit (Cell-Based ELISA) - LS-F2317 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate Range 0.156-10 ng/ml

Mouse/Human Phospho-SNAI1 / SNAIL-1 (Ser246) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1439 from LifeSpan Bioscience Category ELISA Kit Prices $550.00 Sizes 1 plate Range 0.156-10 ng/ml

Human SNAI1 / SNAIL-1 ELISA Kit (Sandwich ELISA) - LS-F8875 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 0.063 ng/ml Range 0.156-10 ng/ml

Snail Homolog 1 (SNAI1), Human, ELISA Kit - SEK089Hu from ARP American Research Products Category ELISA Kit Prices $720.00 Sizes 96 t Sensitivity 0.054ng/mL Range 0.156-10ng/mL

SNAI1 (Human) IP-WB Antibody Pair - H00006615-PW1 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

SNAI1 (Human) IP-WB Antibody Pair - H00006615-PW2 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

SNAI1 (Human) Matched Antibody Pair - H00006615-AP51 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

SNAI1 Colorimetric Cell-Based ELISA Kit - CB5643 from Assay Biotechnology Category ELISA Kit Prices $380.00, $760.00, $1,140.00 Sizes 1 kit, 2 kits, 3 kits Range > 5000 Cells

SNAI1 (Phospho-Ser246) Colorimetric Cell-Based ELISA Kit - CBP1479 from Assay Biotechnology Category ELISA Kit Prices $480.00, $960.00, $1,440.00 Sizes 1 kit, 2 kits, 3 kits Range > 5000 Cells

Snail Homolog 1, ELISA Kit - MBS077090 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Snail Homolog 1, ELISA Kit - MBS093030 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 5.0 pg/ml. Range 31.2 pg/ml - 1000 pg/ml.

Snail Homolog 1, ELISA Kit - MBS104830 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Snail Homolog 1, ELISA Kit - MBS102065 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Snail Homolog 1, ELISA Kit - MBS051633 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Snail Homolog 1, ELISA Kit - MBS081392 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Snail Homolog 1, ELISA Kit - MBS060152 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

snail homolog 1 (Drosophila) , ELISA Kit - MBS9327397 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Snail Homolog 1 (SNAI1), ELISA Kit - MBS2022010 from MyBioSource Category ELISA Kit Prices $380.00, $565.00, $765.00, $3,130.00, $5,670.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity Typically less than 0.063ng/mL. Range 0.156-10ng/mL

ELISA Kit for Snail Homolog 1 (SNAI1) - SEK089Hu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.063ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA’s were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

ELISA Kit for Snail Homolog 1 (SNAI1) - SEK089Hu from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.063ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA's were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

Human Snail Homolog 1 (SNAI1) ELISA Kit - EKU07380 from Biomatik Category ELISA Kit Prices $735.00, $3,234.00, $5,880.00 Sizes 96 t, 5x96t, 10x96t Sensitivity 0.063 ng/mL Range 0.156-10 ng/mL

Human Snail Homolog 1 ELISA Kit - abx153126 from Abbexa Category ELISA Kit Sensitivity 0.054 ng/ml Range 0.156 ng/ml - 10 ng/ml

Snail Homolog 1 (SNAI1), Human, ELISA Kit - DL-SNAI1-Hu from ARP American Research Products Category ELISA Kit Prices $655.00 Sizes 96 t Range 0.156-10 ng/mL

SNAI1 (Phospho-Ser246) ELISA Kit - DEIA-XYA1973 from Creative Diagnostics Category ELISA Kit

Human SNAI1 ELISA Kit - abx571569 from Abbexa Category ELISA Kit Sensitivity 0.054 ng/ml Range 0.156 ng/ml - 10 ng/ml

Search more