IL6R

Gene Symbol	IL6R
Entrez Gene	3570
Alt Symbol	CD126, IL-6R-1, IL-6RA, IL6Q, IL6RA, IL6RQ, gp80
Species	Human
Gene Type	protein-coding
Description	interleukin 6 receptor
Other Description	CD126 antigen|IL-6 receptor subunit alpha|IL-6R 1|interleukin-6 receptor subunit alpha|membrane glycoprotein 80
Swissprots	Q16202 A8KAE8 B2R6V4 Q5FWG2 Q53EQ7 Q5VZ23 P08887
Accessions	ABK41906 CAI84624 EAW53199 EAW53200 EAW53201 P08887 AA035377 AK223582 BAD97302 AK293013 BAF85702 AK312730 BAG35601 BC035327 BC089410 AAH89410 BC132684 AAI32685 BC132686 AAI32687 BM911928 HQ258435 ADR83189 HQ258616 ADR83368 S72848 AAC60635 X12830 CAA31312 X58298 CAA41231 XM_005245139 XP_005245196 XM_005245140 XP_005245197 XM_006711298 XP_006711361 XM_006711299 XP_006711362 NM_000565 NP_000556 NM_001206866 NP_001193795 NM_181359 NP_852004
Function	Part of the receptor for interleukin 6. Binds to IL6 with low affinity, but does not transduce a signal. Signal activation necessitate an association with IL6ST. Activation may lead to the regulation of the immune response, acute-phase reactions and hematopoiesis.
Subcellular Location	Isoform 1: Basolateral cell membrane; Single-pass type I membrane protein.
Tissue Specificity	Isoform 2 is expressed in peripheral blood mononuclear cells and weakly found in urine and serum.
Top Pathways	Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, Hematopoietic cell lineage, PI3K-Akt signaling pathway, Non-alcoholic fatty liver disease (NAFLD)

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

IL-6 Receptor (Interleukin-6 Receptor) Human SimpleStep ELISA™ Kit - ab181424 from Abcam Category ELISA Kit Prices $484.00 Sizes 1 x 96 tests Sensitivity 46 pg/ml Range 156 pg/ml - 10000 pg/ml

IL-6 Receptor (Interleukin-6 Receptor) Human ELISA Kit - ab46029 from Abcam Category ELISA Kit Prices $489.00, $734.00 Sizes 1 x 96 tests, 2 x 96 tests Sensitivity < 5 pg/ml Range 31.25 pg/ml - 1000 pg/ml

Human IL6R / IL6 Receptor ELISA Kit (Sandwich ELISA) - LS-F5052 from LifeSpan Bioscience Category ELISA Kit Prices $690.00 Sizes 1 plate Sensitivity 0.83 ng/ml Range 6.144-600 pg/ml

Human IL6R / IL6 Receptor ELISA Kit (Sandwich ELISA) - LS-F2676 from LifeSpan Bioscience Category ELISA Kit Prices $530.00 Sizes 1 plate Sensitivity 10 pg/ml Range 6.144-600 pg/ml

Rat IL6R / IL6 Receptor ELISA Kit (Sandwich ELISA) - LS-F4995 from LifeSpan Bioscience Category ELISA Kit Prices $740.00 Sizes 1 plate Sensitivity 0.067 ng/ml Range 6.144-600 pg/ml

Mouse IL6R / IL6 Receptor ELISA Kit (Sandwich ELISA) - LS-F264 from LifeSpan Bioscience Category ELISA Kit Prices $520.00, $930.00, $2,140.00 Sizes 1 plate, 2 plate, 5 plate Sensitivity 6.144 pg/ml Range 6.144-600 pg/ml

Human IL6R / IL6 Receptor ELISA Kit (Sandwich ELISA) - LS-F1001 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate Range 6.144-600 pg/ml

Mouse IL6R / IL6 Receptor ELISA Kit (Sandwich ELISA) - LS-F7705 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity 0.148 ng/ml Range 6.144-600 pg/ml

Human IL6R / IL6 Receptor ELISA Kit (Sandwich ELISA) - LS-F11804 from LifeSpan Bioscience Category ELISA Kit Prices $530.00 Sizes 1 plate Sensitivity 62.5 Range 6.144-600 pg/ml

Human IL-6 sR ELISA Kit - RAB0313 from Sigma-Aldrich Category ELISA Kit Prices $423.50 Sizes 1 kt

Human IL-6 R alpha Luminex Performance Assay - LBA227 from R&D Systems

Human IL-6 R alpha Quantikine ELISA Kit - DR600 from R&D Systems Category ELISA Kit Prices $509.00, $2,440.00, $16,540.00 Sizes 1 kit, 1 pack (6 Plates), 1 pack (50 Plates) Sensitivity 15.1 pg/mL Range 31.2 - 2,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Citrate Plasma, Urine)

Human IL-6 R alpha Quantikine PharmPak (50 Plates) - PDR600 from R&D Systems Category ELISA Kit Sensitivity 15.1 pg/mL Range 31.2 - 2,000 pg/mL (Serum, Heparin Plasma, Cell Culture Supernates, Citrate Plasma, EDTA Plasma, Urine)

Human IL-6 R alpha Quantikine SixPak (6 Plates) - SR600 from R&D Systems Category ELISA Kit Sensitivity 15.1 pg/mL Range 31.2 - 2,000 pg/mL (Serum, Heparin Plasma, Cell Culture Supernates, Citrate Plasma, EDTA Plasma, Urine)

Mouse IL-6 R alpha DuoSet ELISA - DY1830 from R&D Systems Category ELISA Kit Prices $649.00 Sizes 1 kit (for 15 Plates) Range 46.90 - 3,000 pg/mL

Human IL-6 R alpha DuoSet ELISA - DY227 from R&D Systems Category ELISA Kit Prices $649.00 Sizes 1 kit (for 15 Plates) Range 15.60 - 1,000 pg/mL

Mouse IL-6 R alpha Quantikine ELISA Kit - MR600 from R&D Systems Category ELISA Kit Prices $479.00 Sizes 1 kit Sensitivity 0.07 ng/mL Range 0.2 - 12 ng/mL (Cell Culture Supernates, Serum, Heparin Plasma)

IL-6R ELISA Kit (Human) : 96 Wells (OKAG00149) - OKAG00149 from Aviva Systems Biology Category ELISA Kit Prices $390.00 Sizes 96 wells Sensitivity 16 pg/mL Range 16-1,000 pg/mL

Human CD126 ELISA Kit - abx056059 from Abbexa Category ELISA Kit

Human IL6R ELISA Kit - abx151950 from Abbexa Category ELISA Kit Sensitivity 0.05 ng/ml Range 1.875 ng/ml - 120 ng/ml

Interleukin 6 Receptor, IL-6R, Human, ELISA Kit - E-EL-H0192 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 18.75 Range 31.25-2000pg/mL

Interleukin 6 receptor (IL-6R), Human, ELISA Kit - CSB-E16524h from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Interleukin 6 Receptor (IL6R), Human, ELISA Kit - SEB815Hu from ARP American Research Products Category ELISA Kit Prices $685.00 Sizes 96 t Sensitivity 0.67ng/mL Range 1.88-120ng/mL

Interleukin 6 receptor, Human, ELISA Kit - E01I0206 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

Interleukin-6 receptor subunit alpha, IL6R, Human, ELISA Kit - E1815h from ARP American Research Products Category ELISA Kit Prices $476.00 Sizes 96 t Range 62.5-4000 pg/mL

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