IL6R

Gene Symbol IL6R
Entrez Gene 3570
Alt Symbol CD126, IL-6R-1, IL-6RA, IL6Q, IL6RA, IL6RQ, gp80
Species Human
Gene Type protein-coding
Description interleukin 6 receptor
Other Description CD126 antigen|IL-6 receptor subunit alpha|IL-6R 1|interleukin-6 receptor subunit alpha|membrane glycoprotein 80
Swissprots Q16202 A8KAE8 B2R6V4 Q5FWG2 Q53EQ7 Q5VZ23 P08887
Accessions ABK41906 CAI84624 EAW53199 EAW53200 EAW53201 P08887 AA035377 AK223582 BAD97302 AK293013 BAF85702 AK312730 BAG35601 BC035327 BC089410 AAH89410 BC132684 AAI32685 BC132686 AAI32687 BM911928 HQ258435 ADR83189 HQ258616 ADR83368 S72848 AAC60635 X12830 CAA31312 X58298 CAA41231 XM_005245139 XP_005245196 XM_005245140 XP_005245197 XM_006711298 XP_006711361 XM_006711299 XP_006711362 NM_000565 NP_000556 NM_001206866 NP_001193795 NM_181359 NP_852004
Function Part of the receptor for interleukin 6. Binds to IL6 with low affinity, but does not transduce a signal. Signal activation necessitate an association with IL6ST. Activation may lead to the regulation of the immune response, acute-phase reactions and hematopoiesis.
Subcellular Location Isoform 1: Basolateral cell membrane; Single-pass type I membrane protein.
Tissue Specificity Isoform 2 is expressed in peripheral blood mononuclear cells and weakly found in urine and serum.
Top Pathways Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, Hematopoietic cell lineage, PI3K-Akt signaling pathway, Non-alcoholic fatty liver disease (NAFLD)

IL-6Rα (B-N12) - sc-65328 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal

IL-6Rα (2B2.3) - sc-71366 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal

IL-6Rα (H-300) - sc-13947 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
IL-6Rα (H-300): sc-13947. Western blot analysis of IL-6Rα expression in HeLa (A) and Hep G2 (B) whole cell lysates.

IL-6Rα (H-7) - sc-373708 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
IL-6Rα (H-7): sc-373708. Western blot analysis of IL-6Rα expression in HeLa (A) and BJAB (B) whole cell lysates.

IL-6Rα (C-20) - sc-661 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
IL-6Rα (C-20): sc-661. Western blot analysis of IL-6 receptor α expression in HeLa (A) and BJAB (B) whole cell lysates.

Anti-IL6R antibody - ab128008 from Abcam

Prices $378.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-IL6R antibody (ab128008) at 1/200 dilutionLane 1 : Jurkat cell lysateLane 2 : 803 cell lysate

Anti-IL6R antibody - ab103798 from Abcam

Prices $378.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-IL6R antibody (ab103798) at 5 µg/ml + HeLa cell lysate at 50 µg

Anti-IL6R antibody - ab180617 from Abcam

Host Rabbit
Clonality Polyclonal
All lanes : Anti-IL6R antibody (ab180617) at 1/500 dilutionLane 1 : SW480 cell line extractLane 2 : H480 cell line extractLane 3 : HepG2 cell line extract

Anti-IL6R antibody - ab85105 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-IL6R antibody (ab85105) at 1/200 dilutionLane 1 : Jurkat cell lysateLane 2 : 803 cell lysate

Anti-IL6R antibody - ab156362 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-IL6R antibody (ab156362) at 1 µg/mlLane 1 : Thymus (Human) Tissue Lysate - adult normal tissue (ab30146)Lane 2 : Spleen (Human) Tissue Lysate - adult normal tissue (ab29699)Lysates/proteins at 10 µg per lane.SecondaryGoat Anti-Rabbit IgG H&L (HRP) (ab97051) at 1/10000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-IL6R antibody [B-F19] - ab27405 from Abcam

Prices $378.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone B-F19
Ab27405, staining IL6R by FACS.

Anti-IL6R antibody [B-N12] - ab27404 from Abcam

Prices $376.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone B-N12
Ab27404, staining IL6R in U266 cell line by FACS.

Anti-IL6R antibody [B-R6] - ab47215 from Abcam

Prices $384.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone B-R6
ab47215 staining IL6R on U266 cell line.

Anti-IL6R antibody [B-R6] - ab47173 from Abcam

Prices $370.00
Sizes 1 ml
Host Mouse
Clonality Monoclonal
Clone B-R6

Anti-IL6R antibody [B-R6] (FITC) - ab27321 from Abcam

Prices $190.00
Sizes 50 tests
Host Mouse
Clonality Monoclonal
Clone B-R6
ab27321 at 10µl/106 cells staining IL6R in U266 cell line by Flow Cytometry.

Anti-IL6R / IL6 Receptor Antibody (clone B-R6) - LS-C5855 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone B-R6

Anti-IL6R / IL6 Receptor Antibody (FITC) - LS-C5856 from LifeSpan Bioscience

Prices $485.00
Sizes 100 tst
Host Mouse
Clonality Monoclonal

Anti-IL6R / IL6 Receptor Antibody - LS-C5854 from LifeSpan Bioscience

Prices $465.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-IL6R / IL6 Receptor Antibody - LS-C7992 from LifeSpan Bioscience

Prices $530.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-IL6R / IL6 Receptor Antibody (clone B-R6, Azide-free, Low Endotoxin) - LS-C7993 from LifeSpan Bioscience

Prices $495.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone B-R6

Anti-IL6R / IL6 Receptor Antibody (clone B-R6) - LS-C7995 from LifeSpan Bioscience

Prices $485.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone B-R6

Anti-IL6R / IL6 Receptor Antibody (Biotin) - LS-C7996 from LifeSpan Bioscience

Prices $560.00
Sizes 100 tst
Host Mouse
Clonality Monoclonal

Anti-IL6R / IL6 Receptor Antibody (clone B-R6) - LS-C45194 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone B-R6

Anti-IL6R / IL6 Receptor Antibody (PE) - LS-C70917 from LifeSpan Bioscience

Prices $495.00
Sizes 100 tst
Host Mouse
Clonality Monoclonal

Anti-IL6R / IL6 Receptor Antibody (Extracellular Domain) - LS-C70918 from LifeSpan Bioscience

Prices $575.00
Sizes 500 µg
Host Rat
Clonality Monoclonal
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