IL6R

Gene Symbol IL6R
Entrez Gene 3570
Alt Symbol CD126, IL-6R-1, IL-6RA, IL6Q, IL6RA, IL6RQ, gp80
Species Human
Gene Type protein-coding
Description interleukin 6 receptor
Other Description CD126 antigen|IL-6 receptor subunit alpha|IL-6R 1|interleukin-6 receptor subunit alpha|membrane glycoprotein 80
Swissprots Q16202 A8KAE8 B2R6V4 Q5FWG2 Q53EQ7 Q5VZ23 P08887
Accessions ABK41906 CAI84624 EAW53199 EAW53200 EAW53201 P08887 AA035377 AK223582 BAD97302 AK293013 BAF85702 AK312730 BAG35601 BC035327 BC089410 AAH89410 BC132684 AAI32685 BC132686 AAI32687 BM911928 HQ258435 ADR83189 HQ258616 ADR83368 S72848 AAC60635 X12830 CAA31312 X58298 CAA41231 XM_005245139 XP_005245196 XM_005245140 XP_005245197 XM_006711298 XP_006711361 XM_006711299 XP_006711362 NM_000565 NP_000556 NM_001206866 NP_001193795 NM_181359 NP_852004
Function Part of the receptor for interleukin 6. Binds to IL6 with low affinity, but does not transduce a signal. Signal activation necessitate an association with IL6ST. Activation may lead to the regulation of the immune response, acute-phase reactions and hematopoiesis.
Subcellular Location Isoform 1: Basolateral cell membrane; Single-pass type I membrane protein.
Tissue Specificity Isoform 2 is expressed in peripheral blood mononuclear cells and weakly found in urine and serum.
Top Pathways Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, Hematopoietic cell lineage, PI3K-Akt signaling pathway, Non-alcoholic fatty liver disease (NAFLD)

IL-6Rα CRISPR/Cas9 KO Plasmid (h) - sc-400582 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

IL-6Rα HDR Plasmid (h) - sc-400582-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

IL-6Rα Double Nickase Plasmid (h) - sc-400582-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

IL-6Rα Double Nickase Plasmid (h2) - sc-400582-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

IL-6Rα CRISPR Activation Plasmid (h) - sc-400582-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

IL-6Rα CRISPR Activation Plasmid (h2) - sc-400582-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

IL-6Rα Lentiviral Activation Particles (h) - sc-400582-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

IL-6Rα Lentiviral Activation Particles (h2) - sc-400582-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

IL-6Rα siRNA (h) - sc-35663 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

IL-6Rα shRNA Plasmid (h) - sc-35663-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

IL-6Rα shRNA (h) Lentiviral Particles - sc-35663-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

IL6R RNAi - H00003570-R03 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

IL6R RNAi - H00003570-R04 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU140561 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN1097 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1097 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

IL6R siRNA (Human) - CRH2387 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

IL6R - MBS8233946 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human IL6R (NM_000565.3) - SHH319057 from Creative biogene

Category siRNA
Species Reactivities Human

Human IL6R siRNA - orb262889 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

IL6R shRNA Plasmid (Human) - CHH2387 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

IL6R miRNA 3'UTR clone - MiUTR1H-04925 from Creative biogene

Species Reactivities Human
Search more