IL6R

Gene Symbol	IL6R
Entrez Gene	3570
Alt Symbol	CD126, IL-6R-1, IL-6RA, IL6Q, IL6RA, IL6RQ, gp80
Species	Human
Gene Type	protein-coding
Description	interleukin 6 receptor
Other Description	CD126 antigen|IL-6 receptor subunit alpha|IL-6R 1|interleukin-6 receptor subunit alpha|membrane glycoprotein 80
Swissprots	Q16202 A8KAE8 B2R6V4 Q5FWG2 Q53EQ7 Q5VZ23 P08887
Accessions	ABK41906 CAI84624 EAW53199 EAW53200 EAW53201 P08887 AA035377 AK223582 BAD97302 AK293013 BAF85702 AK312730 BAG35601 BC035327 BC089410 AAH89410 BC132684 AAI32685 BC132686 AAI32687 BM911928 HQ258435 ADR83189 HQ258616 ADR83368 S72848 AAC60635 X12830 CAA31312 X58298 CAA41231 XM_005245139 XP_005245196 XM_005245140 XP_005245197 XM_006711298 XP_006711361 XM_006711299 XP_006711362 NM_000565 NP_000556 NM_001206866 NP_001193795 NM_181359 NP_852004
Function	Part of the receptor for interleukin 6. Binds to IL6 with low affinity, but does not transduce a signal. Signal activation necessitate an association with IL6ST. Activation may lead to the regulation of the immune response, acute-phase reactions and hematopoiesis.
Subcellular Location	Isoform 1: Basolateral cell membrane; Single-pass type I membrane protein.
Tissue Specificity	Isoform 2 is expressed in peripheral blood mononuclear cells and weakly found in urine and serum.
Top Pathways	Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, Hematopoietic cell lineage, PI3K-Akt signaling pathway, Non-alcoholic fatty liver disease (NAFLD)

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human-IL6R-cDNA-Clone - DC14796 from Abgent, a WuXi AppTec company Prices $631.80 Sizes 10 µg Species Human Accession BC132686

Human IL-6 R alpha (NP_000556) VersaClone cDNA - RDC1155 from R&D Systems Prices $199.00 Sizes 10 µg Species Human

IL6R - MBS1268287 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC132686

IL6R - MBS1268395 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC132684

Human IL6R ORF Clone(NM_000565.3) - CDCL167175 from Creative Biomart Species Human Accession NM_000565.3

Human IL6R ORF Clone(NM_000565.3) - CDCL167176 from Creative Biomart Species Human Accession NM_000565.3

Human IL6R/IL-6R/CD126 transcript variant 1 Gene ORF cDNA clone in cloning vector - HG10398-M from Sino Biological Species Human

Human IL6R/IL-6R/CD126 transcript variant 1 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG10398-ACR from Sino Biological Species Human

Human IL6R/IL-6R/CD126 transcript variant 1 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG10398-ACG from Sino Biological Species Human

Human IL6R/IL-6R/CD126 transcript variant 1 Gene ORF cDNA clone expression plasmid, N-His tag - HG10398-NH from Sino Biological Species Human

Human IL6R/IL-6R/CD126 transcript variant 1 Gene ORF cDNA clone expression plasmid, C-His tag - HG10398-CH from Sino Biological Species Human

Human IL6R/IL-6R/CD126 transcript variant 1 Gene ORF cDNA clone expression plasmid - HG10398-UT from Sino Biological Species Human

Human IL6R/IL-6R/CD126 transcript variant 1 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG10398-NF from Sino Biological Species Human

Human IL6R/IL-6R/CD126 transcript variant 1 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG10398-NM from Sino Biological Species Human

Human IL6R/IL-6R/CD126 transcript variant 1 Gene ORF cDNA clone expression plasmid, C-HA tag - HG10398-CY from Sino Biological Species Human

Human IL6R/IL-6R/CD126 transcript variant 1 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG10398-CF from Sino Biological Species Human

Human IL6R/IL-6R/CD126 transcript variant 1 Gene ORF cDNA clone expression plasmid, N-HA tag - HG10398-NY from Sino Biological Species Human

Human IL6R/IL-6R/CD126 transcript variant 1 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG10398-CM from Sino Biological Species Human

Rhesus IL6R/IL-6R/CD126 Gene ORF cDNA clone expression plasmid, C-HA tag - CG90324-CY from Sino Biological Species Monkey

Rhesus IL6R/IL-6R/CD126 Gene ORF cDNA clone expression plasmid, C-Myc tag - CG90324-CM from Sino Biological Species Monkey

Rhesus IL6R/IL-6R/CD126 Gene ORF cDNA clone expression plasmid, N-His tag - CG90324-NH from Sino Biological Species Monkey

Rhesus IL6R/IL-6R/CD126 Gene ORF cDNA clone expression plasmid, C-His tag - CG90324-CH from Sino Biological Species Monkey

Rhesus IL6R/IL-6R/CD126 Gene ORF cDNA clone expression plasmid, N-HA tag - CG90324-NY from Sino Biological Species Monkey

Rhesus IL6R/IL-6R/CD126 Gene ORF cDNA clone expression plasmid, N-Myc tag - CG90324-NM from Sino Biological Species Monkey

Mouse IL-6 R alpha (NP_034689) VersaClone cDNA - RDC1436 from R&D Systems Prices $199.00 Sizes 10 µg Species Mouse

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