IL6R

Gene Symbol	IL6R
Entrez Gene	3570
Alt Symbol	CD126, IL-6R-1, IL-6RA, IL6Q, IL6RA, IL6RQ, gp80
Species	Human
Gene Type	protein-coding
Description	interleukin 6 receptor
Other Description	CD126 antigen|IL-6 receptor subunit alpha|IL-6R 1|interleukin-6 receptor subunit alpha|membrane glycoprotein 80
Swissprots	Q16202 A8KAE8 B2R6V4 Q5FWG2 Q53EQ7 Q5VZ23 P08887
Accessions	ABK41906 CAI84624 EAW53199 EAW53200 EAW53201 P08887 AA035377 AK223582 BAD97302 AK293013 BAF85702 AK312730 BAG35601 BC035327 BC089410 AAH89410 BC132684 AAI32685 BC132686 AAI32687 BM911928 HQ258435 ADR83189 HQ258616 ADR83368 S72848 AAC60635 X12830 CAA31312 X58298 CAA41231 XM_005245139 XP_005245196 XM_005245140 XP_005245197 XM_006711298 XP_006711361 XM_006711299 XP_006711362 NM_000565 NP_000556 NM_001206866 NP_001193795 NM_181359 NP_852004
Function	Part of the receptor for interleukin 6. Binds to IL6 with low affinity, but does not transduce a signal. Signal activation necessitate an association with IL6ST. Activation may lead to the regulation of the immune response, acute-phase reactions and hematopoiesis.
Subcellular Location	Isoform 1: Basolateral cell membrane; Single-pass type I membrane protein.
Tissue Specificity	Isoform 2 is expressed in peripheral blood mononuclear cells and weakly found in urine and serum.
Top Pathways	Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, Hematopoietic cell lineage, PI3K-Akt signaling pathway, Non-alcoholic fatty liver disease (NAFLD)

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

IL6R-Over-expression-Lysate - LY11806a from Abgent, a WuXi AppTec company Category Cell Lysate Prices $325.00 Sizes 100 µg

IL6R 293T Cell Transient Overexpression Lysate(Denatured) - H00003570-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

IL6R overexpression lysate - LY405751 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

IL6R 293 Cell Lysate - 403711 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

IL6R Overexpression Lysate (Denatured) - H00003570-T01 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

IL6R Over-expression Lysate Product - GWB-93D4FD from Genway Biotech Category Cell Lysate Prices $445.00 Sizes 100 µg Species Human

Human IL6R / CD126 HEK293 Cell Lysate (WB positive control) - 10398-H08HL-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Human

IL6R Overexpression Lysate (Native) - NBP2-04920 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

IL6R Overexpression Lysate (Native) - NBP2-04164 from Novus Biologicals Category Cell Lysate Prices $529.00 Sizes 100 µg

Human IL6R Human Cells Transfected Lysate (positive control) (denatured) - orb172954 from Biorbyt Category Cell Lysate Prices $604.00 Sizes 300 μg Species Human

Panoply™ Human IL6R Knockdown Stable Cell Line - CSC-DC007611 from Creative biogene Category Cell Line Species Human

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