IL6R

Gene Symbol	IL6R
Entrez Gene	3570
Alt Symbol	CD126, IL-6R-1, IL-6RA, IL6Q, IL6RA, IL6RQ, gp80
Species	Human
Gene Type	protein-coding
Description	interleukin 6 receptor
Other Description	CD126 antigen|IL-6 receptor subunit alpha|IL-6R 1|interleukin-6 receptor subunit alpha|membrane glycoprotein 80
Swissprots	Q16202 A8KAE8 B2R6V4 Q5FWG2 Q53EQ7 Q5VZ23 P08887
Accessions	ABK41906 CAI84624 EAW53199 EAW53200 EAW53201 P08887 AA035377 AK223582 BAD97302 AK293013 BAF85702 AK312730 BAG35601 BC035327 BC089410 AAH89410 BC132684 AAI32685 BC132686 AAI32687 BM911928 HQ258435 ADR83189 HQ258616 ADR83368 S72848 AAC60635 X12830 CAA31312 X58298 CAA41231 XM_005245139 XP_005245196 XM_005245140 XP_005245197 XM_006711298 XP_006711361 XM_006711299 XP_006711362 NM_000565 NP_000556 NM_001206866 NP_001193795 NM_181359 NP_852004
Function	Part of the receptor for interleukin 6. Binds to IL6 with low affinity, but does not transduce a signal. Signal activation necessitate an association with IL6ST. Activation may lead to the regulation of the immune response, acute-phase reactions and hematopoiesis.
Subcellular Location	Isoform 1: Basolateral cell membrane; Single-pass type I membrane protein.
Tissue Specificity	Isoform 2 is expressed in peripheral blood mononuclear cells and weakly found in urine and serum.
Top Pathways	Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, Hematopoietic cell lineage, PI3K-Akt signaling pathway, Non-alcoholic fatty liver disease (NAFLD)

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human IL6R protein fragment - ab167742 from Abcam Category Protein Prices $410.00 Sizes 50 µg Source HEK 293 cells Species Human

Human IL6R full length protein - ab50082 from Abcam Category Protein Source HEK 293 cells Species Human

Human IL6R protein fragment - ab53370 from Abcam Category Protein Source E. coli Species Human

IL6R / IL6 Receptor Blocking Peptide - LS-E26035 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Human IL6R Biologically Active Protein - NBP2-35347 from Novus Biologicals Category Protein Prices $69.00, $169.00 Sizes 5 µg, 20 µg Source Baculovirus Species Human

IL6R Partial Recombinant Protein - H00003570-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

IL6R Recombinant Protein - H00003570-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Species Human

IL6R Recombinant Protein - H00003570-G01 from Novus Biologicals Category Protein Prices $579.00 Sizes 10 µg Species Human

Interleukin-6-Receptor-Peptide - SP2442b from Abgent, a WuXi AppTec company Category Peptide Prices $185.00 Sizes 5 mg

Interleukin-6-Receptor-Peptide - SP2442a from Abgent, a WuXi AppTec company Category Peptide Prices $100.00 Sizes 1 mg

Soluble IL-6 Receptor alpha Recombinant Protein (Active) - GTX48184-PRO from GeneTex Category Protein Prices $299.00 Sizes 20 μg Source Human Species Human

IL6 Receptor (isoform 1) blocking peptide - GTX89399-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human

Recombinant Human IL-6 R alpha - 227-SR-025 from R&D Systems Category Protein Source Spodoptera frugiperda, Sf 21 (baculovirus)-derived, Leu20-Asp358

Recombinant Human IL-6 R alpha, CF - 227-SR-025/CF from R&D Systems Category Protein Source Spodoptera frugiperda, Sf 21 (baculovirus)-derived, Leu20-Asp358

sIL 6R Protein (OPPA00551) - OPPA00551 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 5 µg Source E. coli

Human Interleukin 6 Receptor Protein - abx067543 from Abbexa Category Protein Source E.coli Species Human

IL6R Peptide - AC21-0863-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

CD126 / IL6R - PA234 from Acris Antibodies Category Protein Prices $135.00 Sizes 5 µg Source HEK293 cells Species Human

CD126 / IL6R - PA234X from Acris Antibodies Category Protein Prices $235.00 Sizes 20 µg Source HEK293 cells Species Human

CD126 / IL6R - H00003570-G01 from Acris Antibodies Category Protein Prices $550.00 Sizes 10 µg Species Human

CD126 / IL6R - H00003570-P01 from Acris Antibodies Category Protein Prices $340.00 Sizes 2 µg Species Human

CD126 / IL6R - H00003570-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

CD126 / IL6R - H00003570-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

CD126 / IL6R - P5842 from Acris Antibodies Category Protein Prices $500.00 Sizes 20 µg Species Human

CD126 / IL6R - P6154 from Acris Antibodies Category Protein Prices $580.00 Sizes 20 µg Species Human

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