PDGFB

Gene Symbol	PDGFB
Entrez Gene	5155
Alt Symbol	IBGC5, PDGF-2, PDGF2, SIS, SSV, c-sis
Species	Human
Gene Type	protein-coding
Description	platelet-derived growth factor beta polypeptide
Other Description	PDGF subunit B|PDGF, B chain|becaplermin|platelet-derived growth factor 2|platelet-derived growth factor B chain|platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)|platelet-derived growth factor subunit B|platelet-derived growth factor, beta polypeptide (oncogene SIS)|proto-oncogene c-Sis
Swissprots	P01127 P78431 Q15354 Q9UF23 Q6FHE7 G3XAG8
Accessions	AAA60349 AAA60552 AAA98793 CAA02289 CAA02294 CAA25226 CAA25227 CAA25228 CAA25229 CAA25230 CAA67262 CAE82038 CAH23424 CAI06107 CAJ32895 CAJ32907 CAL32766 CBH30542 EAW60305 EAW60306 EAW60307 EAW60308 P01127 AK022920 BC029822 AAH29822 BC077725 AAH77725 BM983641 CR456538 CAG30424 CR541807 CAG46606 CU013138 CAK54569 CU013426 CAK54868 M12783 AAA60553 M32009 X02744 CAA26524 X02811 CAA26579 X03702 CAA27333 X83705 CAA58679 NM_002608 NP_002599 NM_033016 NP_148937
Function	Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Required for normal proliferation and recruitment of pericytes and vascular smooth muscle cells in the central nervous system, skin, lung, heart and placenta. Required for normal blood vessel development, and for normal development of kidney glomeruli. Plays an important role in wound healing. Signaling is modulated by the formation of heterodimers with PDGFA (By similarity). {ECO:0000250}.
Subcellular Location	Secreted. Note=Released by platelets upon wounding.
Tissue Specificity	Expressed at high levels in the heart, brain (sustantia nigra), placenta and fetal kidney. Expressed at moderate levels in the brain (hippocampus), skeletal muscle, kidney and lung. {ECO:0000269|PubMed:11331882}.
Top Pathways	Rap1 signaling pathway, PI3K-Akt signaling pathway, MicroRNAs in cancer, Choline metabolism in cancer, Cytokine-cytokine receptor interaction

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

PDGF BB Human ELISA Kit - ab100624 from Abcam Category ELISA Kit Prices $489.00 Sizes 1 x 96 tests Sensitivity < 1 pg/ml Range 0.549 pg/ml - 400 pg/ml

PDGF BB Human ELISA Kit - ab100625 from Abcam Category ELISA Kit Prices $489.00 Sizes 1 x 96 tests Sensitivity < 1 pg/ml Range 0.549 pg/ml - 400 pg/ml

PDGF BB Human SimpleStep ELISA™ Kit - ab184860 from Abcam Category ELISA Kit Prices $484.00 Sizes 1 x 96 tests Sensitivity 2.1 pg/ml Range 2 pg/ml - 1500 pg/ml

PDGF Receptor beta Human ELISA Kit - ab100626 from Abcam Category ELISA Kit Prices $489.00 Sizes 1 x 96 tests Sensitivity < 25 pg/ml Range 24.69 pg/ml - 18000 pg/ml

Human PDGF-BB ELISA Kit (Sandwich ELISA) - LS-F5139 from LifeSpan Bioscience Category ELISA Kit Prices $650.00 Sizes 1 plate Sensitivity 25.9 pg/ml Range 46.88-3000 pg/ml

Rat PDGF-BB ELISA Kit (Sandwich ELISA) - LS-F5140 from LifeSpan Bioscience Category ELISA Kit Prices $780.00 Sizes 1 plate Sensitivity 13.2 pg/ml Range 46.88-3000 pg/ml

Human PDGF-BB ELISA Kit (Sandwich ELISA) - LS-F4534 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 6.3 pg/ml Range 46.88-3000 pg/ml

Pig PDGF-BB ELISA Kit (Sandwich ELISA) - LS-F5748 from LifeSpan Bioscience Category ELISA Kit Prices $860.00 Sizes 1 plate Sensitivity 19.64 pg/ml Range 46.88-3000 pg/ml

Human PDGF-BB ELISA Kit (Sandwich ELISA) - LS-F472 from LifeSpan Bioscience Category ELISA Kit Prices $460.00, $840.00, $1,960.00 Sizes 1 plate, 2 plate, 5 plate Sensitivity 0.549 pg/ml Range 46.88-3000 pg/ml

Human PDGF-BB ELISA Kit (Sandwich ELISA) - LS-F593 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate Range 46.88-3000 pg/ml

Mouse/Human/Rat PDGF-BB ELISA Kit (Cell-Based ELISA) - LS-F2231 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate Range 46.88-3000 pg/ml

Mouse PDGF-BB ELISA Kit (Sandwich ELISA) - LS-F12287 from LifeSpan Bioscience Category ELISA Kit Prices $530.00 Sizes 1 plate Sensitivity 31.2 Range 46.88-3000 pg/ml

Pig PDGF-BB ELISA Kit (Sandwich ELISA) - LS-F12288 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity 78 Range 46.88-3000 pg/ml

Human PDGF-BB ELISA Kit (Sandwich ELISA) - LS-F12289 from LifeSpan Bioscience Category ELISA Kit Prices $530.00 Sizes 1 plate Sensitivity 31.2 pg/ml Range 46.88-3000 pg/ml

Human PDGF-BB ELISA Kit - RAB0397 from Sigma-Aldrich Category ELISA Kit Prices $423.50 Sizes 1 kt

Human PDGF-BB ELISA Kit - RAB0398 from Sigma-Aldrich Category ELISA Kit Prices $438.50 Sizes 1 kt

Human PDGF-BB Biotinylated Fluorokine Flow Cytometry Kit - NFPDBB from R&D Systems Prices $405.00 Sizes 1 kit

Human PDGF-BB Luminex Performance Assay - LAN220 from R&D Systems

Human PDGF-BB Magnetic Luminex Performance Assay - LANM220 from R&D Systems

Human PDGF-BB Quantikine ELISA Kit - DBB00 from R&D Systems Category ELISA Kit Prices $519.00, $2,491.00, $16,868.00 Sizes 1 kit, 1 pack (6 Plates), 1 pack (50 Plates) Sensitivity 15 pg/mL Range 31.2 - 2,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma)

Human PDGF-BB Quantikine PharmPak (50 Plates) - PDBB00 from R&D Systems Category ELISA Kit Sensitivity 15 pg/mL Range 31.2 - 2,000 pg/mL (Serum, Heparin Plasma, Cell Culture Supernates, EDTA Plasma)

Human PDGF-BB Quantikine SixPak (6 Plates) - SBB00 from R&D Systems Category ELISA Kit Sensitivity 15 pg/mL Range 31.2 - 2,000 pg/mL (Serum, Heparin Plasma, Cell Culture Supernates, EDTA Plasma)

Mouse/Rat PDGF-BB Quantikine ELISA Kit - MBB00 from R&D Systems Category ELISA Kit Prices $479.00 Sizes 1 kit Sensitivity 19.3 pg/mL Range 31.2 - 2,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma)

Human PDGF-BB DuoSet ELISA - DY220 from R&D Systems Category ELISA Kit Prices $649.00 Sizes 1 kit (for 15 Plates) Range 31.20 - 2,000 pg/mL

Mouse/Rat PDGF-BB DuoSet ELISA, 5 Plate - DY8464-05 from R&D Systems Category ELISA Kit Prices $299.00 Sizes 1 kit (for 5 Plates) Range 62.50 - 4,000 pg/mL

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