KLK7

Gene Symbol	KLK7
Entrez Gene	5650
Alt Symbol	PRSS6, SCCE, hK7
Species	Human
Gene Type	protein-coding
Description	kallikrein-related peptidase 7
Other Description	kallikrein 7 (chymotryptic, stratum corneum)|kallikrein-7|serine protease 6|signal protein|stratum corneum chymotryptic enzyme
Swissprots	A8K0U5 Q8N5N9 Q8NFV7 P49862
Accessions	AAD49718 AAG33360 AAK69624 CAA02644 CAG17626 EAW71958 EAW71959 EAW71960 EAW71961 P49862 AA101043 AF411214 AAN03662 AF411215 AAN03663 AI049783 AK289660 BAF82349 AK295313 BAG58291 AY601109 AAU04540 AY646152 AAT66047 BC032005 AAH32005 DA243628 DA307925 DQ018784 AAY97797 DQ890746 ABM81672 DQ893916 ABM84842 KF963189 AHN52223 KF963190 KF963191 KF963192 AHN52224 KF963193 L33404 AAC37551 NM_001243126 NP_001230055 NM_001207053 NP_001193982 NM_005046 NP_005037 NM_139277 NP_644806
Function	May catalyze the degradation of intercellular cohesive structures in the cornified layer of the skin in the continuous shedding of cells from the skin surface. Specific for amino acid residues with aromatic side chains in the P1 position. Cleaves insulin A chain at '14-Tyr-|-Gln-15' and insulin B chain at '6- Leu-|-Cys-7', '16-Tyr-|-Leu-17', '25-Phe-|-Tyr-26' and '26-Tyr-|- Thr-27'. Could play a role in the activation of precursors to inflammatory cytokines. {ECO:0000269|PubMed:23370777}.
Subcellular Location	Secreted {ECO:0000269|PubMed:12738725}. Note=In ovarian carcinoma, secreted and also observed at the apical membrane and in cytoplasm at the invasive front.
Tissue Specificity	Abundantly expressed in the skin and is expressed by keratinocytes in the epidermis. Also expressed in the brain, mammary gland, cerebellum, spinal cord and kidney. Lower levels in salivary glands, uterus, thymus, thyroid, placenta, trachea and testis. Up-regulated in ovarian carcinoma, especially late-stage serous carcinoma, compared with normal ovaries and benign adenomas (at protein level). {ECO:0000269|PubMed:10974542, ECO:0000269|PubMed:12738725}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human KLK7 / Kallikrein 7 ELISA Kit (Sandwich ELISA) - LS-F5717 from LifeSpan Bioscience Category ELISA Kit Prices $580.00 Sizes 1 plate Sensitivity 0.156 ng/ml Range 0.156-10 ng/ml

Mouse KLK7 / Kallikrein 7 ELISA Kit (Sandwich ELISA) - LS-F7650 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity 78 pg/ml Range 0.156-10 ng/ml

Human KLK7 / Kallikrein 7 EIA Kit - LS-F9887 from LifeSpan Bioscience Category ELISA Kit Prices $690.00 Sizes 1 plate Sensitivity 43.8 pg/ml Range 123.46 - 10000 pg/ml

Human KLK7 / Kallikrein 7 ELISA Kit (Sandwich ELISA) - LS-F11890 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 0.312 Range 0.156-10 ng/ml

Kallikrein 7 (KLK7), Human, ELISA Kit - SEB910Hu from ARP American Research Products Category ELISA Kit Prices $580.00 Sizes 96 t Sensitivity 0.065ng/mL Range 0.156-10ng/mL

Kallikrein 7, KLK 7, Human, ELISA Kit - CSB-E13797h from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t Sensitivity 0.156 ng/ml Range 0.625 ng/ml-40 ng/ml

Kallikrein-7, KLK7, Human, ELISA Kit - E1910h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 0.312-20 ng/mL

Kallikrein 7, KLK7, Human, ELISA Kit - E-EL-H0500 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 0.094 Range 0.156-10ng/mL

Kallikrein 7, KLK7, Rabbit, ELISA Kit - E-EL-RB0661 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Kallikrein 7, KLK7, Chicken, ELISA Kit - E-EL-Ch2149 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t

Kallikrein 7, KLK7, Porcine, ELISA Kit - E-EL-P1415 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Kallikrein 7, KLK7, Sheep, ELISA Kit - E-EL-S0237 from ARP American Research Products Category ELISA Kit Prices $648.00 Sizes 96 t

Kallikrein 7, KLK7, Monkey, ELISA Kit - E-EL-MK0676 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Custom Human Kallikrein 7 ELISA - ELH-KLK7 from RayBiotech Category ELISA Kit Prices $615.00, $1,107.00, $2,460.00 Sizes 1 plate kit, 2 plate kit, 5 plate kit

Human KLK7 ELISA Kit - HK0081 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Anserine KLK7 ELISA Kit - AK0081 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

kallikrein-related peptidase 7, ELISA Kit - MBS702381 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of human KLK7 is typically less than 0.156 ng/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations. Range 0.625 ng/ml -40 ng/ml.

Human KLK7(Kallikrein 7) ELISA Kit - E-EL-H0500 from Elabscience Category ELISA Kit Sensitivity 0.10 ng/mL Range 0.16—10 ng/mL

Human KLK7 (Kallikrein 7) CLIA Kit - E-CL-H0405 from Elabscience Category CLIA Kit Sensitivity 18.75 pg/mL Range Average Recovery (%)

Kallikrein 7, ELISA Kit - MBS738562 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Kallikrein 7, ELISA Kit - MBS729863 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Kallikrein 7, ELISA Kit - MBS021519 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Kallikrein 7, ELISA Kit - MBS731413 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Kallikrein 7, ELISA Kit - MBS038684 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Kallikrein 7, ELISA Kit - MBS737311 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.1 ng/mL.

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