DKK4

Gene Symbol	DKK4
Entrez Gene	27121
Alt Symbol	DKK-4
Species	Human
Gene Type	protein-coding
Description	dickkopf WNT signaling pathway inhibitor 4
Other Description	dickkopf-4|dickkopf-related protein 4|hDkk-4
Swissprots	Q3KNX0 Q9UBT3 Q9Y4C3
Accessions	BAA33475 CAR82119 EAW63220 Q9UBT3 AB017788 BAA33438 AF177397 AAF02677 AK301609 BAG63095 BC107046 AAI07047 BC107047 AAI07048 BX105775 XM_011544486 XP_011542788 XM_011544487 XP_011542789 XM_011544488 XP_011542790 XM_011544489 XP_011542791 NM_014420 NP_055235
Function	Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero- posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease (By similarity). {ECO:0000250}.
Subcellular Location	Secreted.
Tissue Specificity	Expressed in cerebellum, T-cells, esophagus and lung.
Top Pathways	Wnt signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human-DKK4-cDNA-Clone - DC09445 from Abgent, a WuXi AppTec company Prices $302.40 Sizes 10 µg Species Human Accession BC107047

DKK4 - MBS1275989 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC107047

Human DKK4 cDNA clone(NM_014420.2) - CDFH005129 from Creative Biomart Species Human Accession NM_014420.2

Human DKK4 ORF clone(NM_014420.2) - CDCL183927 from Creative Biomart Species Human Accession NM_014420.2

Human DKK4 ORF Clone(NM_014420.2) - CDCR297539 from Creative Biomart Species Human Accession NM_014420.2

Human DKK4 ORF Clone(NM_014420.2) - CDCR297540 from Creative Biomart Species Human Accession NM_014420.2

Human DKK4 ORF Clone(NM_014420.2) - CDCR297541 from Creative Biomart Species Human Accession NM_014420.2

Human DKK4 ORF Clone(NM_014420.2) - CDCL161142 from Creative Biomart Species Human Accession NM_014420.2

Human DKK4 Gene cDNA clone plasmid - HG11570-M from Sino Biological Species Human

Human DKK4 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG11570-CF from Sino Biological Species Human

Human DKK4 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG11570-NM from Sino Biological Species Human

Human DKK4 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG11570-ACR from Sino Biological Species Human

Human DKK4 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG11570-CM from Sino Biological Species Human

Human DKK4 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG11570-ACG from Sino Biological Species Human

Human DKK4 Gene ORF cDNA clone expression plasmid - HG11570-UT from Sino Biological Species Human

Human DKK4 Gene ORF cDNA clone expression plasmid, N-HA tag - HG11570-NY from Sino Biological Species Human

Human DKK4 Gene ORF cDNA clone expression plasmid, N-His tag - HG11570-NH from Sino Biological Species Human

Human DKK4 Gene ORF cDNA clone expression plasmid, C-HA tag - HG11570-CY from Sino Biological Species Human

Human DKK4 Gene ORF cDNA clone expression plasmid, C-His tag - HG11570-CH from Sino Biological Species Human

Human DKK4 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG11570-NF from Sino Biological Species Human

Human DKK4 ORF clone(NM_014420.2) - CDCL183927 from Creative biogene Species Human

Human DKK4 ORF Clone (BC107047) - CDCS413618 from Creative biogene Species Human Accession Q9UBT3

Human DKK4 cDNA Clone(NM_014420.2) - CDFH005129 from Creative biogene Species Human

Human Dickkopf 4 Gene - orb92274 from Biorbyt Prices $264.00 Sizes 10 μg Species Human

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