CCL21

Gene Symbol CCL21
Entrez Gene 6366
Alt Symbol 6Ckine, CKb9, ECL, SCYA21, SLC, TCA4
Species Human
Gene Type protein-coding
Description chemokine (C-C motif) ligand 21
Other Description C-C motif chemokine 21|Efficient Chemoattractant for Lymphocytes|beta chemokine exodus-2|secondary lymphoid tissue chemokine|small inducible cytokine subfamily A (Cys-Cys), member 21
Swissprots O00585
Accessions AAQ13417 ABK41948 CAA06653 EAW58415 O00585 AB002409 BAA21817 AF001979 AAB86594 AK311901 BAG34842 AY358887 AAQ89246 BC027918 AAH27918 BI833188 BP331359 CR450326 CAG29322 DQ892048 ABM82974 DQ895242 ABM86168 U88320 AAB91454 XM_011518004 XP_011516306 NM_002989 NP_002980
Function Inhibits hemopoiesis and stimulates chemotaxis. Chemotactic in vitro for thymocytes and activated T-cells, but not for B-cells, macrophages, or neutrophils. Shows preferential activity towards naive T-cells. May play a role in mediating homing of lymphocytes to secondary lymphoid organs. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4.
Subcellular Location Secreted.
Tissue Specificity Highly expressed in high endothelial venules of lymph nodes, spleen and appendix. Intermediate levels found in small intestine, thyroid gland and trachea. Low level expression in thymus, bone marrow, liver, and pancreas. Also found in tonsil, fetal heart and fetal spleen.
Top Pathways Cytokine-cytokine receptor interaction, Chemokine signaling pathway

6CKine (FL-134) - sc-25445 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
6CKine (FL-134): sc-25445. Western blot analysis of 6CKine expression in mouse thymus tissue extract.

6CKine (C-15) - sc-5808 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
6CKine (C-15): sc-5808. Western blot analysis of human recombinant 6CKine.

Anti-CCL21 antibody - ab9851 from Abcam

Prices $378.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC image of ab9851 staining in human normal lymph node formalin fixed paraffin embedded tissue section, performed on a Leica BondTM system using the standard protocol F. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH6, epitope retrieval solution 1) for 20 mins. The section was then incubated with ab9851, 1µg/ml, for 15 mins at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.For other IHC staining systems (automated and non-automated) customers should optimize variable parameters such as antigen retrieval conditions, primary antibody concentration and antibody incubation times.

Anti-CCL21 antibody - ab197760 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin-embedded Human cervical cancer tissue labeling CCL21 with ab197760 at 1/40 dilution.

Anti-CCL21 antibody - ab156948 from Abcam

Prices $376.00
Sizes 200 µl
Host Goat
Clonality Polyclonal
Anti-CCL21 antibody (ab156948) at 0.1 µg/ml + Human lymph node lysate at 35 µgdeveloped using the ECL technique

Anti-CCL21 antibody - ab167506 from Abcam

Prices $376.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-CCL21 antibody (ab167506) at 1 µg/mlLane 1 : CCL21 transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 15 µl per lane.SecondaryGoat anti-Mouse IgG HRP at 1/2500 dilution

Anti-CCL21 antibody - ab36770 from Abcam

Prices $370.00
Sizes 50 µg
Host Chicken
Clonality Polyclonal

Anti-CCL21 antibody [EPR6218] - ab129014 from Abcam

Prices $378.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR6218
All lanes : Anti-CCL21 antibody [EPR6218] (ab129014) at 1/1000 dilutionLane 1 : Human CCL21 recombinant protein at 0.01 µgLane 2 : Caco 2 cell lysate at 10 µgSecondaryHRP labelled Goat anti-Rabbit IgG at 1/2000 dilution

Anti-CCL21 antibody [MM0146-2H26] - ab89396 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone MM0146-2H26
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human placental tissue section (4µm) labelling CCL21 with ab89396. Tissue was treated with 15µg/ml Protenase K for antigen retrieval and fixed with 4% PFA. A HRP-conjugated anti-mouse IgG was used as the secondary antibody (30 minutes at room temperature) followed by DAB color development.

Anti-Exodus 2 antibody (Biotin) - ab83130 from Abcam

Prices $370.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-CCL21 / SLC Antibody (aa491-509) - LS-C312875 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
CCL21 / Exodus 2 / SLC antibody. IHC(P): Rat Cardiac Muscle Tissue.

Anti-CCL21 / SLC Antibody - LS-C15104 from LifeSpan Bioscience

Prices $425.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-CCL21 / SLC Antibody - LS-C48901 from LifeSpan Bioscience

Prices $445.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-CCL21 / SLC Antibody (Biotin) - LS-C104622 from LifeSpan Bioscience

Prices $285.00, $325.00
Sizes 25 µg, 50 µg
Host Rabbit
Clonality Polyclonal

Anti-CCL21 / SLC Antibody (aa23-52, AP) - LS-C253744 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CCL21 / SLC Antibody (Biotin) - LS-C190359 from LifeSpan Bioscience

Prices $590.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-CCL21 / SLC Antibody (aa23-52, Azide-free, HRP) - LS-C253747 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CCL21 / SLC Antibody (aa23-52, APC) - LS-C253745 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CCL21 / SLC Antibody - LS-C285468 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-CCL21 / SLC Antibody (aa23-52, PE) - LS-C253748 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CCL21 / SLC Antibody (aa5-130, Biotin) - LS-C297270 from LifeSpan Bioscience

Prices $425.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-CCL21 / SLC Antibody (aa5-130, FITC) - LS-C302990 from LifeSpan Bioscience

Prices $445.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-CCL21 / SLC Antibody (aa5-132, Biotin) - LS-C297283 from LifeSpan Bioscience

Prices $435.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-CCL21 / SLC Antibody (aa24-134, Biotin) - LS-C299553 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-CCL21 / SLC Antibody (aa5-132, FITC) - LS-C303004 from LifeSpan Bioscience

Prices $465.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
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