CCL21

Gene Symbol	CCL21
Entrez Gene	6366
Alt Symbol	6Ckine, CKb9, ECL, SCYA21, SLC, TCA4
Species	Human
Gene Type	protein-coding
Description	chemokine (C-C motif) ligand 21
Other Description	C-C motif chemokine 21|Efficient Chemoattractant for Lymphocytes|beta chemokine exodus-2|secondary lymphoid tissue chemokine|small inducible cytokine subfamily A (Cys-Cys), member 21
Swissprots	O00585
Accessions	AAQ13417 ABK41948 CAA06653 EAW58415 O00585 AB002409 BAA21817 AF001979 AAB86594 AK311901 BAG34842 AY358887 AAQ89246 BC027918 AAH27918 BI833188 BP331359 CR450326 CAG29322 DQ892048 ABM82974 DQ895242 ABM86168 U88320 AAB91454 XM_011518004 XP_011516306 NM_002989 NP_002980
Function	Inhibits hemopoiesis and stimulates chemotaxis. Chemotactic in vitro for thymocytes and activated T-cells, but not for B-cells, macrophages, or neutrophils. Shows preferential activity towards naive T-cells. May play a role in mediating homing of lymphocytes to secondary lymphoid organs. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4.
Subcellular Location	Secreted.
Tissue Specificity	Highly expressed in high endothelial venules of lymph nodes, spleen and appendix. Intermediate levels found in small intestine, thyroid gland and trachea. Low level expression in thymus, bone marrow, liver, and pancreas. Also found in tonsil, fetal heart and fetal spleen.
Top Pathways	Cytokine-cytokine receptor interaction, Chemokine signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Exodus 2 (CCL21) Human SimpleStep ELISA™ Kit - ab193759 from Abcam Category ELISA Kit Prices $484.00 Sizes 1 x 96 tests Sensitivity 3.8 pg/ml Range 9 pg/ml - 600 pg/ml

Human CCL21 / SLC ELISA Kit (Sandwich ELISA) - LS-F2573 from LifeSpan Bioscience Category ELISA Kit Prices $530.00 Sizes 1 plate Sensitivity 12 pg/ml Range 15.63-500 pg/ml

Human CCL21 / SLC ELISA Kit (Sandwich ELISA) - LS-F3975 from LifeSpan Bioscience Category ELISA Kit Prices $690.00 Sizes 1 plate Sensitivity 12.3 pg/ml Range 15.63-500 pg/ml

Mouse CCL21 / SLC ELISA Kit (Sandwich ELISA) - LS-F216 from LifeSpan Bioscience Category ELISA Kit Prices $460.00, $840.00, $1,960.00 Sizes 1 plate, 2 plate, 5 plate Sensitivity 15.63 pg/ml Range 15.63-500 pg/ml

Human CCL21 / SLC ELISA Kit (Sandwich ELISA) - LS-F23 from LifeSpan Bioscience Category ELISA Kit Prices $460.00, $840.00, $1,960.00 Sizes 1 plate, 2 plate, 5 plate Sensitivity 30 pg/ml Range 15.63-500 pg/ml

Mouse CCL21 / SLC ELISA Kit (Sandwich ELISA) - LS-F8154 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity 7.8 pg/ml Range 15.63-500 pg/ml

Human CCL21 / 6ckine ELISA Kit - RAB0062 from Sigma-Aldrich Category ELISA Kit Prices $666.00 Sizes 1 kt

CCL21/6Ckine BioAssay™ ELISA Kit, Human - 143749 from USBiological Life Science Category ELISA Kit Sensitivity < 12 pg/ml Range 62.5pg/ml-4000pg/ml

Human CCL21/6Ckine Biotin Fluorokine Flow Cytometry Kit - NFCCL21 from R&D Systems Prices $405.00 Sizes 1 kit

Mouse CCL21/6Ckine DuoSet ELISA - DY457 from R&D Systems Category ELISA Kit Prices $649.00 Sizes 1 kit (for 15 Plates) Range 15.60 - 1,000 pg/mL

Human CCL21/6Ckine DuoSet ELISA - DY366 from R&D Systems Category ELISA Kit Prices $649.00 Sizes 1 kit (for 15 Plates) Range 62.50 - 4,000 pg/mL

Human CCL21 ELISA Kit - abx056040 from Abbexa Category ELISA Kit

C-C motif chemokine 21, CCL21, Human, ELISA Kit - E1575h from ARP American Research Products Category ELISA Kit Prices $536.00 Sizes 96 t

CCL21/6Ckine, Human, ELISA Kit - PB-0555 from ARP American Research Products Category ELISA Kit Prices $418.00 Sizes 96 t Sensitivity < 12 pg/ml Range 62.5pg/ml-4000pg/ml

Secondary Lymphoid Tissue Chemokine (SLC), Human, ELISA Kit - SEB575Hu from ARP American Research Products Category ELISA Kit Prices $685.00 Sizes 96 t Sensitivity 12.3pg/mL Range 31.2-2,000pg/mL

Secondary Lymphoid Tissue Chemokine, Human, ELISA Kit - E01S0111 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t Sensitivity 1.0pg/ml Range 100-2500pg/mL,

Secondary lymphoid-tissue chemokine, SLC, Human, ELISA Kit - CSB-E04521h from ARP American Research Products Category ELISA Kit Prices $550.00, $790.00, $791.00, $794.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t Sensitivity 20 pg/ml Range 78 pg/ml-5000 pg/ml

Secondary Lymphoid Tissue Chemokine, SLC, Human, ELISA Kit - E-EL-H0028 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 46.875 Range 78.125-5000pg/mL

Secondary Lymphoid Tissue Chemokine, SLC, Mouse, ELISA Kit - E-EL-M0145 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t Sensitivity 9.375 Range 15.625-1000pg/mL

Secondary Lymphoid Tissue Chemokine, SLC, Rat, ELISA Kit - E-EL-R0627 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t Sensitivity 37.5 Range 62.5-4000pg/mL

Secondary Lymphoid Tissue Chemokine, SLC/CCL21, Rabbit, ELISA Kit - E-EL-RB0519 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Secondary Lymphoid Tissue Chemokine, SLC/CCL21, Chicken, ELISA Kit - E-EL-Ch1093 from ARP American Research Products Category ELISA Kit Prices $504.00 Sizes 96 t

Secondary Lymphoid Tissue Chemokine, SLC/CCL21, Porcine, ELISA Kit - E-EL-P2087 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Secondary Lymphoid Tissue Chemokine, SLC/CCL21, Monkey, ELISA Kit - E-EL-MK0924 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t Sensitivity 0.094 Range 0.156-10ng/mL

Secondary Lymphoid Tissue Chemokine (SLC), Human, CLIA Kit - SCB575Hu from ARP American Research Products Category CLIA Kit Prices $840.00 Sizes 96 t Sensitivity 9.3pg/mL Range 31.2-2,000pg/mL

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