CCL21

Gene Symbol	CCL21
Entrez Gene	6366
Alt Symbol	6Ckine, CKb9, ECL, SCYA21, SLC, TCA4
Species	Human
Gene Type	protein-coding
Description	chemokine (C-C motif) ligand 21
Other Description	C-C motif chemokine 21|Efficient Chemoattractant for Lymphocytes|beta chemokine exodus-2|secondary lymphoid tissue chemokine|small inducible cytokine subfamily A (Cys-Cys), member 21
Swissprots	O00585
Accessions	AAQ13417 ABK41948 CAA06653 EAW58415 O00585 AB002409 BAA21817 AF001979 AAB86594 AK311901 BAG34842 AY358887 AAQ89246 BC027918 AAH27918 BI833188 BP331359 CR450326 CAG29322 DQ892048 ABM82974 DQ895242 ABM86168 U88320 AAB91454 XM_011518004 XP_011516306 NM_002989 NP_002980
Function	Inhibits hemopoiesis and stimulates chemotaxis. Chemotactic in vitro for thymocytes and activated T-cells, but not for B-cells, macrophages, or neutrophils. Shows preferential activity towards naive T-cells. May play a role in mediating homing of lymphocytes to secondary lymphoid organs. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4.
Subcellular Location	Secreted.
Tissue Specificity	Highly expressed in high endothelial venules of lymph nodes, spleen and appendix. Intermediate levels found in small intestine, thyroid gland and trachea. Low level expression in thymus, bone marrow, liver, and pancreas. Also found in tonsil, fetal heart and fetal spleen.
Top Pathways	Cytokine-cytokine receptor interaction, Chemokine signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human CCL21 gene - orb91057 from Biorbyt Prices $255.00 Sizes 10 μg Species Human

Human-CCL21-cDNA-Clone - DC05707 from Abgent, a WuXi AppTec company Prices $180.90 Sizes 10 µg Species Human Accession BC027918

CCL21 - MBS1276817 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC027918

Human CCL21/6Ckine Gene ORF cDNA clone in cloning vector - HG10477-M from Sino Biological Species Human

Human CCL21/6Ckine Gene ORF cDNA clone expression plasmid, N-Flag tag - HG10477-NF from Sino Biological Species Human

Human CCL21/6Ckine Gene ORF cDNA clone expression plasmid, N-Myc tag - HG10477-NM from Sino Biological Species Human

Human CCL21/6Ckine Gene ORF cDNA clone expression plasmid, C-HA tag - HG10477-CY from Sino Biological Species Human

Human CCL21/6Ckine Gene ORF cDNA clone expression plasmid, C-Flag tag - HG10477-CF from Sino Biological Species Human

Human CCL21/6Ckine Gene ORF cDNA clone expression plasmid, N-HA tag - HG10477-NY from Sino Biological Species Human

Human CCL21/6Ckine Gene ORF cDNA clone expression plasmid, C-Myc tag - HG10477-CM from Sino Biological Species Human

Human CCL21/6Ckine Gene ORF cDNA clone expression plasmid, C-His tag - HG10477-CH from Sino Biological Species Human

Human CCL21/6Ckine Gene ORF cDNA clone expression plasmid, C-Flag tag - HG10477-M-F from Sino Biological Species Human

Human CCL21/6Ckine Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG10477-ACR from Sino Biological Species Human

Human CCL21 Gene cDNA Clone (full-length ORF Clone) expression ready, untagged - HG10477-M-N from Sino Biological Species Human Accession NM_002989.2

Human CCL21/6Ckine Gene ORF cDNA clone expression plasmid - HG10477-UT from Sino Biological Species Human

Human CCL21/6Ckine Gene ORF cDNA clone expression plasmid, N-His tag - HG10477-NH from Sino Biological Species Human

Human CCL21/6Ckine Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG10477-ACG from Sino Biological Species Human

CCL21 - CL01337H01 from Elabscience Species Human Accession NM_002989.2

Human CCL21 ORF clone(NM_002989.2) - CDCL183098 from Creative biogene Species Human

Human CCL21 ORF Clone (BC027918) - CDCS411083 from Creative biogene Species Human Accession O00585

Human CCL21 cDNA Clone(NM_002989.2) - CDFH002939 from Creative biogene Species Human

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