NR1I2

Gene Symbol	NR1I2
Entrez Gene	8856
Alt Symbol	BXR, ONR1, PAR, PAR1, PAR2, PARq, PRR, PXR, SAR, SXR
Species	Human
Gene Type	protein-coding
Description	nuclear receptor subfamily 1, group I, member 2
Other Description	nuclear receptor subfamily 1 group I member 2|orphan nuclear receptor PAR1|orphan nuclear receptor PXR|pregnane X nuclear receptor variant 2|pregnane X receptor|steroid and xenobiotic receptor
Swissprots	Q9UJ27 Q9UJ22 Q006P5 Q9UJ25 Q008C8 Q9UJ24 Q96AC7 O75469 Q9UJ26 Q9UNW4 Q9UJ23
Accessions	AAG23345 AAK38720 AAK38721 AAK38722 ABJ52965 ABJ52966 ABR09276 EAW79537 EAW79538 EAW79539 O75469 AB307701 BAH02292 AF061056 AAD05436 AF084644 AAC64557 AF084645 AAC64558 AJ009936 CAB55489 AJ009937 CAB55492 AK122990 BAG53837 AK223456 AK310789 AY091855 AAM26736 BC017304 AAH17304 HQ692837 ADZ17348 HQ709177 ADZ17384 NM_003889 NP_003880 NM_022002 NP_071285 NM_033013 NP_148934
Function	Nuclear receptor that binds and is activated by variety of endogenous and xenobiotic compounds. Transcription factor that activates the transcription of multiple genes involved in the metabolism and secretion of potentially harmful xenobiotics, drugs and endogenous compounds. Activated by the antibiotic rifampicin and various plant metabolites, such as hyperforin, guggulipid, colupulone, and isoflavones. Response to specific ligands is species-specific. Activated by naturally occurring steroids, such as pregnenolone and progesterone. Binds to a response element in the promoters of the CYP3A4 and ABCB1/MDR1 genes. {ECO:0000269|PubMed:11297522, ECO:0000269|PubMed:11668216, ECO:0000269|PubMed:12578355, ECO:0000269|PubMed:18768384, ECO:0000269|PubMed:19297428, ECO:0000269|PubMed:9727070}.
Subcellular Location	Nucleus {ECO:0000255|PROSITE- ProRule:PRU00407, ECO:0000269|PubMed:12606758}.
Tissue Specificity	Expressed in liver, colon and small intestine.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human NR1I2 / PXR ELISA Kit (Sandwich ELISA) - LS-F6765 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 0.126 ng/ml Range 0.313-20 ng/ml

Rat NR1I2 / PXR ELISA Kit (Sandwich ELISA) - LS-F7615 from LifeSpan Bioscience Category ELISA Kit Prices $780.00 Sizes 1 plate Sensitivity 0.113 ng/ml Range 0.313-20 ng/ml

Mouse NR1I2 / PXR ELISA Kit (Sandwich ELISA) - LS-F12189 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 0.156 Range 0.313-20 ng/ml

Human NR1I2 / PXR ELISA Kit (Sandwich ELISA) - LS-F12190 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 0.156 Range 0.313-20 ng/ml

Human Pregnane X Receptor ELISA Kit - abx152818 from Abbexa Category ELISA Kit Sensitivity 0.125 ng/ml Range 0.313 ng/ml - 20 ng/ml

Nuclear receptor subfamily 1 group I member 2, NR1I2, Human, ELISA Kit - E10641h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 0.156-10 ng/mL

Pregnane X Receptor (PXR), Human, ELISA Kit - SED950Hu from ARP American Research Products Category ELISA Kit Prices $720.00 Sizes 96 t Sensitivity 0.062ng/mL Range 0.156-10ng/mL

Pregnane X Receptor, PXR, Human, ELISA Kit - E-EL-H2423 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 0.094 Range 0.156-10ng/mL

Pregnane X Receptor, PXR, Rabbit, ELISA Kit - E-EL-RB1950 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Pregnane X Receptor, PXR, Chicken, ELISA Kit - E-EL-Ch2016 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t

Pregnane X Receptor, PXR, Porcine, ELISA Kit - E-EL-P0087 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Pregnane X Receptor, PXR, Sheep, ELISA Kit - E-EL-S0510 from ARP American Research Products Category ELISA Kit Prices $648.00 Sizes 96 t

Pregnane X Receptor, PXR, Guinea Pig, ELISA Kit - E-EL-GP0578 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t

Pregnane X Receptor, PXR, Monkey, ELISA Kit - E-EL-MK2099 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Human PXR(Pregnane X Receptor) ELISA Kit - E-EL-H2423 from Elabscience Category ELISA Kit Sensitivity 0.10 ng/mL Range 0.16—10 ng/mL

Rabbit PXR (Pregnane X Receptor) ELISA Kit - E-EL-RB1950 from Elabscience Category ELISA Kit

Human PXR (Pregnane X Receptor) CLIA Kit - E-CL-H1425 from Elabscience Category CLIA Kit Sensitivity 18.75 pg/mL Range Average Recovery (%)

nuclear receptor subfamily 1, group H, member 4 (NR1H4), ELISA Kit - MBS7205854 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

nuclear receptor subfamily 1, group I, member 2, ELISA Kit - MBS9326391 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 10 pg/ml. Range 62.5 pg/ml - 2000 pg/ml.

Pregnane X Receptor, ELISA Kit - MBS053025 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Pregnane X Receptor, ELISA Kit - MBS095027 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Pregnane X Receptor, ELISA Kit - MBS049260 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Pregnane X Receptor, ELISA Kit - MBS088486 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Pregnane X Receptor, ELISA Kit - MBS082863 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Pregnane X Receptor, ELISA Kit - MBS096206 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.1ng/ml. Range 0.625ng/ml-20ng/ml.

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