SOCS4

Gene Symbol	SOCS4
Entrez Gene	122809
Alt Symbol	SOCS7
Species	Human
Gene Type	protein-coding
Description	suppressor of cytokine signaling 4
Other Description	SH2 domain containing SOCS box protein|SOCS-4|SOCS-7|suppressor of cytokine signaling 7
Swissprots	Q8WXH5
Accessions	EAW80655 Q8WXH5 AF424815 AAL60517 AK056685 AK124083 BAG54001 AK126195 AK127299 BC060790 AAH60790 BX161418 CAD61893 BX648734 CD109883 CR933659 CAI45958 HQ448516 ADQ32995 XM_011536425 XP_011534727 XM_011536426 XP_011534728 NM_080867 NP_543143 NM_199421 NP_955453
Function	SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. Substrate-recognition component of a SCF-like ECS (Elongin BC- CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Inhibits EGF signaling by mediating the degradation of the Tyr-phosphorylated EGF receptor/EGFR. {ECO:0000269|PubMed:15590694, ECO:0000269|PubMed:17997974}.
Top Pathways	Jak-STAT signaling pathway, Insulin signaling pathway, Type II diabetes mellitus, Prolactin signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human SOCS4 full length protein - ab153591 from Abcam Category Protein Source Wheat germ Species Human

SOCS4 Antibody Blocking Peptide - LS-E1259 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SOCS4 Antibody Blocking Peptide - LS-E3374 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SOCS4 Antibody Blocking Peptide - LS-E25315 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SOCS7 / SOCS-7 Antibody Blocking Peptide - LS-E4739 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SOCS7 / SOCS-7 Antibody Blocking Peptide - LS-E26876 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SOCS-7/Nck/NAP4 Partial Recombinant Protein - H00030837-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

SOCS4-Antibody-Center-Blocking-peptide - BP11847c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

SOCS4-Antibody-Center-Blocking-Peptide - BP14548c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

SOCS7 blocking peptide - GTX88488-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human

SOCS7 Blocking Peptide - 33R-4853 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

SOCS4 Peptide - AC21-0143-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

SOCS4 - H00122809-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

SOCS4 - H00122809-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

SOCS4 Peptide - 46-410P from ProSci Category Peptide Species Human

Recombinant Human Suppressor of cytokine signaling 4(SOCS4) - CSB-YP022393HU CSB-EP022393HU CSB-BP022393HU CSB-MP022393HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

SOCS4 Protein - abx163068 from Abbexa Category Protein Species Human

SOCS4 (full length, N-term HIS tag, transcript variant 1) - TP760721 from Acris Antibodies Category Protein Prices $199.00 Sizes 50 µg Source E. coli Species Human

SOCS4 (full length, N-term HIS tag, transcript variant 2) - TP760840 from Acris Antibodies Category Protein Prices $199.00 Sizes 50 µg Source E. coli Species Human

SOCS4, Peptide - MBS425492 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Pig, Bovine

SOCS-7/Nck/NAP4 Recombinant Protein Antigen - NBP2-13363PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

SOCS7 Peptide, Human - M34GP14880H from Creative Peptides Category Peptide Source Synthetic. Species Human

SOCS7 Immunizing peptide - orb55023 from Biorbyt Category Peptide Prices $247.00 Sizes 100 μg

SOCS-4 Recombinant Protein Antigen - NBP2-58238PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

Suppressor of cytokine signaling 4 (SOCS4), Recombinant Protein - MBS1401951 from MyBioSource Category Protein Prices $1,220.00, $1,220.00, $1,440.00, $1,440.00, $1,975.00, $1,975.00, $2,440.00, $2,440.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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