Gene Symbol | TNFAIP1 |
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Entrez Gene | 7126 |
Alt Symbol | B12, B61, BTBD34, EDP1, hBACURD2 |
Species | Human |
Gene Type | protein-coding |
Description | tumor necrosis factor, alpha-induced protein 1 (endothelial) |
Other Description | BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2|BTB/POZ domain-containing protein TNFAIP1 |
Swissprots | B7Z6M4 Q5TZQ1 Q13829 |
Accessions | AAL38649 EAW51077 Q13829 AK300584 BAH13310 AK312387 BAG35304 BC001643 AAH01643 BC001949 AAH01949 BC003694 BT020121 AAV38924 CR456819 CAG33100 DB093553 DQ892758 ABM83684 DQ896003 ABM86981 M80783 AAA58385 NM_021137 NP_066960 |
Function | Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in regulation of cytoskeleton structure. The BCR(BACURD2) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome, thereby regulating the actin cytoskeleton and cell migration. Its interaction with RHOB may regulate apoptosis. May enhance the PCNA-dependent DNA polymerase delta activity. {ECO:0000269|PubMed:19637314, ECO:0000269|PubMed:19782033}. |
Subcellular Location | Cytoplasm. Nucleus. Endosome. Note=Colocalizes with RHOB in endosomes. |
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 (TNFAIP1), Human, ELISA Kit - E01B0980 from ARP American Research Products
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BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 (TNFAIP1), ELISA Kit - MBS7207695 from MyBioSource
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BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 (TNFAIP1), ELISA Kit - MBS7248156 from MyBioSource
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BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 (TNFAIP1), ELISA Kit - MBS7235113 from MyBioSource
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BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 (TNFAIP1), ELISA Kit - MBS7239745 from MyBioSource
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BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 (TNFAIP1), ELISA Kit - MBS7238216 from MyBioSource
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BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 (TNFAIP1), ELISA Kit - MBS7233906 from MyBioSource
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BTB/POZ domain containing adapter for CUL3 mediated RhoA degradation protein 2 (TNFAIP1), ELISA Kit - MBS7212478 from MyBioSource
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BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 (TNFAIP1), ELISA Kit - MBS7203205 from MyBioSource
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BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 (TNFAIP1), ELISA Kit - MBS7216283 from MyBioSource
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BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 (TNFAIP1), ELISA Kit - MBS7216307 from MyBioSource
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BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 (TNFAIP1), ELISA Kit - MBS7219674 from MyBioSource
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BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 (TNFAIP1), ELISA Kit - MBS7223779 from MyBioSource
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Human TNFAIP1 ELISA Kit - E005380 from Biobool
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anti-TNFAIP1 antibody - ARG55388 from Arigo Biolaboratories
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anti-TNFAIP1 antibody - ARG65676 from Arigo Biolaboratories
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anti-TNFAIP1 antibody - ARG65795 from Arigo Biolaboratories
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