TNFAIP1

Gene Symbol	TNFAIP1
Entrez Gene	7126
Alt Symbol	B12, B61, BTBD34, EDP1, hBACURD2
Species	Human
Gene Type	protein-coding
Description	tumor necrosis factor, alpha-induced protein 1 (endothelial)
Other Description	BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2|BTB/POZ domain-containing protein TNFAIP1
Swissprots	B7Z6M4 Q5TZQ1 Q13829
Accessions	AAL38649 EAW51077 Q13829 AK300584 BAH13310 AK312387 BAG35304 BC001643 AAH01643 BC001949 AAH01949 BC003694 BT020121 AAV38924 CR456819 CAG33100 DB093553 DQ892758 ABM83684 DQ896003 ABM86981 M80783 AAA58385 NM_021137 NP_066960
Function	Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in regulation of cytoskeleton structure. The BCR(BACURD2) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome, thereby regulating the actin cytoskeleton and cell migration. Its interaction with RHOB may regulate apoptosis. May enhance the PCNA-dependent DNA polymerase delta activity. {ECO:0000269|PubMed:19637314, ECO:0000269|PubMed:19782033}.
Subcellular Location	Cytoplasm. Nucleus. Endosome. Note=Colocalizes with RHOB in endosomes.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Recombinant Human TNFAIP1 Protein - H00007126-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

TNFAIP1 / EDP1 - H00007126-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

TNFAIP1 / EDP1 - H00007126-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

TNFAIP1 Peptide - 8345P from ProSci Category Peptide Species Human

TNFAIP1 fusion protein - ag12941 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

TNFAIP1 fusion protein - Ag0132 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

TNFAIP1 fusion protein - ag7873 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

TNFAIP1 fusion protein - Ag0220 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human Tumor Necrosis Factor, Alpha-Induced Protein 1 (Endothelial), T7-tagged - TNFAIP1-3005H from Creative Biomart Category Protein

TNFAIP1 Blocking Peptide - CBP3342 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat, Monkey

TNF-IP 1 (S122) Peptide - BS2484P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Recombinant Human BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2(TNFAIP1) - CSB-YP622686HU CSB-EP622686HU CSB-BP622686HU CSB-MP622686HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

TNFAIP1 Recombinant Protein Antigen - NBP1-88931PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

TNFAIP1 Recombinant Protein Antigen - NBP1-88930PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

TNFAIP1 Blocking Peptide - abx162204 from Abbexa Category Peptide Species Human, Mouse, Rat, Monkey

TNFAIP1-Blocking-Peptide-C-term - BP5410b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

TNFAIP1 Peptide, Human - M34GP16341H from Creative Peptides Category Peptide Source Synthetic. Species Human

BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 (TNFAIP1), Recombinant Protein - MBS1290813 from MyBioSource Category Protein Prices $1,075.00, $1,075.00, $1,305.00, $1,305.00, $1,685.00, $1,685.00, $2,150.00, $2,150.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

TNFAIP1 Peptide - orb224228 from Biorbyt Category Peptide Species Human, Mouse, Rat, Monkey

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