TNFAIP1

Gene Symbol	TNFAIP1
Entrez Gene	7126
Alt Symbol	B12, B61, BTBD34, EDP1, hBACURD2
Species	Human
Gene Type	protein-coding
Description	tumor necrosis factor, alpha-induced protein 1 (endothelial)
Other Description	BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2|BTB/POZ domain-containing protein TNFAIP1
Swissprots	B7Z6M4 Q5TZQ1 Q13829
Accessions	AAL38649 EAW51077 Q13829 AK300584 BAH13310 AK312387 BAG35304 BC001643 AAH01643 BC001949 AAH01949 BC003694 BT020121 AAV38924 CR456819 CAG33100 DB093553 DQ892758 ABM83684 DQ896003 ABM86981 M80783 AAA58385 NM_021137 NP_066960
Function	Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in regulation of cytoskeleton structure. The BCR(BACURD2) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome, thereby regulating the actin cytoskeleton and cell migration. Its interaction with RHOB may regulate apoptosis. May enhance the PCNA-dependent DNA polymerase delta activity. {ECO:0000269|PubMed:19637314, ECO:0000269|PubMed:19782033}.
Subcellular Location	Cytoplasm. Nucleus. Endosome. Note=Colocalizes with RHOB in endosomes.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human-TNFAIP1-cDNA-Clone - DC00760 from Abgent, a WuXi AppTec company Prices $426.60 Sizes 10 µg Species Human Accession BC001643

TNFAIP1 - MBS1273578 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC001643

Human TNFAIP1 ORF Clone(NM_021137.4) - CDCL179184 from Creative Biomart Species Human Accession NM_021137.4

human TNFAIP1 ORF clone - CDCH093388 from Creative Biomart Species Human Accession NM_021137

human TNFAIP1 ORF clone - CDCH093389 from Creative Biomart Species Human Accession NM_021137

Human TNFAIP1 Gene ORF cDNA clone in cloning vector - HG14716-G from Sino Biological Species Human

Human TNFAIP1 Gene ORF cDNA clone expression plasmid, N-HA tag - HG14716-NY from Sino Biological Species Human

Human TNFAIP1 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG14716-NF from Sino Biological Species Human

Human TNFAIP1 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG14716-ACG from Sino Biological Species Human

Human TNFAIP1 Gene ORF cDNA clone expression plasmid, N-His tag - HG14716-NH from Sino Biological Species Human

Human TNFAIP1 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG14716-CF from Sino Biological Species Human

Human TNFAIP1 Gene ORF cDNA clone expression plasmid, C-His tag - HG14716-CH from Sino Biological Species Human

Human TNFAIP1 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG14716-NM from Sino Biological Species Human

Human TNFAIP1 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG14716-CM from Sino Biological Species Human

Human TNFAIP1 Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - HG14716-ANG from Sino Biological Species Human

Human TNFAIP1 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG14716-ACR from Sino Biological Species Human

Human TNFAIP1 Gene ORF cDNA clone expression plasmid, N-OFPSpark tag - HG14716-ANR from Sino Biological Species Human

Human TNFAIP1 Gene ORF cDNA clone expression plasmid - HG14716-UT from Sino Biological Species Human

Human TNFAIP1 Gene ORF cDNA clone expression plasmid, C-HA tag - HG14716-CY from Sino Biological Species Human

Human TNFAIP1 ORF Clone (BC001643) - CDCS415291 from Creative biogene Species Human Accession Q13829

Human TNFAIP1 ORF clone (BC001643) - CDCB158608 from Creative biogene Species Human

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