TNFAIP1

Gene Symbol TNFAIP1
Entrez Gene 7126
Alt Symbol B12, B61, BTBD34, EDP1, hBACURD2
Species Human
Gene Type protein-coding
Description tumor necrosis factor, alpha-induced protein 1 (endothelial)
Other Description BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2|BTB/POZ domain-containing protein TNFAIP1
Swissprots B7Z6M4 Q5TZQ1 Q13829
Accessions AAL38649 EAW51077 Q13829 AK300584 BAH13310 AK312387 BAG35304 BC001643 AAH01643 BC001949 AAH01949 BC003694 BT020121 AAV38924 CR456819 CAG33100 DB093553 DQ892758 ABM83684 DQ896003 ABM86981 M80783 AAA58385 NM_021137 NP_066960
Function Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in regulation of cytoskeleton structure. The BCR(BACURD2) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome, thereby regulating the actin cytoskeleton and cell migration. Its interaction with RHOB may regulate apoptosis. May enhance the PCNA-dependent DNA polymerase delta activity. {ECO:0000269|PubMed:19637314, ECO:0000269|PubMed:19782033}.
Subcellular Location Cytoplasm. Nucleus. Endosome. Note=Colocalizes with RHOB in endosomes.

TNFAIP1-Over-expression-Lysate - LY14579a from Abgent, a WuXi AppTec company

Category Cell Lysate
Prices $325.00
Sizes 100 µg
Western blot analysis of his-tag TNFAIP1 (arrow) using his tag antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 13) or transiently transfected with theTNFAIP1 gene.

TNFAIP1 Overexpression Lysate (Native) - NBP2-06561 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: TNFAIP1 Overexpression Lysate (Adult Normal) [NBP2-06561] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for TNFAIP1.

Panoply™ Human TNFAIP1 Knockdown Stable Cell Line - CSC-DC016341 from Creative biogene

Category Cell Line
Species Human
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