TNFAIP1

Gene Symbol TNFAIP1
Entrez Gene 7126
Alt Symbol B12, B61, BTBD34, EDP1, hBACURD2
Species Human
Gene Type protein-coding
Description tumor necrosis factor, alpha-induced protein 1 (endothelial)
Other Description BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2|BTB/POZ domain-containing protein TNFAIP1
Swissprots B7Z6M4 Q5TZQ1 Q13829
Accessions AAL38649 EAW51077 Q13829 AK300584 BAH13310 AK312387 BAG35304 BC001643 AAH01643 BC001949 AAH01949 BC003694 BT020121 AAV38924 CR456819 CAG33100 DB093553 DQ892758 ABM83684 DQ896003 ABM86981 M80783 AAA58385 NM_021137 NP_066960
Function Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in regulation of cytoskeleton structure. The BCR(BACURD2) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome, thereby regulating the actin cytoskeleton and cell migration. Its interaction with RHOB may regulate apoptosis. May enhance the PCNA-dependent DNA polymerase delta activity. {ECO:0000269|PubMed:19637314, ECO:0000269|PubMed:19782033}.
Subcellular Location Cytoplasm. Nucleus. Endosome. Note=Colocalizes with RHOB in endosomes.

TNF-IP 1 CRISPR/Cas9 KO Plasmid (h) - sc-409695 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TNF-IP 1 HDR Plasmid (h) - sc-409695-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TNF-IP 1 Double Nickase Plasmid (h) - sc-409695-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TNF-IP 1 Double Nickase Plasmid (h2) - sc-409695-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TNF-IP 1 CRISPR Activation Plasmid (h) - sc-409695-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TNF-IP 1 CRISPR Activation Plasmid (h2) - sc-409695-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TNF-IP 1 Lentiviral Activation Particles (h) - sc-409695-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TNF-IP 1 Lentiviral Activation Particles (h2) - sc-409695-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TNFα-IP 1 siRNA (h) - sc-76696 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TNFα-IP 1 shRNA Plasmid (h) - sc-76696-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TNFα-IP 1 shRNA (h) Lentiviral Particles - sc-76696-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU040661 from Sigma-Aldrich

Category siRNA

CompoZr® Knockout ZFN Kit - CKOZFN21731 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21731 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR11523 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr11523

TNFAIP1 siRNA (Human) - CRH4887 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TNFAIP1 RNAi - H00007126-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

TNFAIP1 - MBS8214282 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human TNFAIP1 (NM_021137.4) - SHH431760 from Creative biogene

Category siRNA
Species Reactivities Human

Human TNFAIP1 siRNA - orb265389 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TNFAIP1 shRNA Plasmid (Human) - CHH4887 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

TNFAIP1 miRNA 3'UTR clone - MiUTR4H-TG09221 from Creative biogene

Species Reactivities Human
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