DKK2

Gene Symbol	DKK2
Entrez Gene	27123
Alt Symbol	DKK-2
Species	Human
Gene Type	protein-coding
Description	dickkopf WNT signaling pathway inhibitor 2
Other Description	dickkopf 2 homolog|dickkopf homolog 2|dickkopf related protein-2|dickkopf-2|dickkopf-related protein 2|hDkk-2
Swissprots	Q9UIU3 B2R6S7 A0AVE9 Q9UBU2
Accessions	BAA87056 EAX06208 EAX06209 Q9UBU2 AB033208 BAA85465 AB033941 BAB20420 AF177395 AAF02675 AK309466 AK312695 BAG35574 AY358414 AAQ88780 BC075077 AAH75077 BC075078 AAH75078 BC126328 AAI26329 BC126330 AAI26331 HQ258135 ADR82889 NM_014421 NP_055236
Function	Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero- posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease (By similarity). {ECO:0000250}.
Subcellular Location	Secreted.
Tissue Specificity	Expressed in heart, brain, skeletal muscle and lung.
Top Pathways	Wnt signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human DKK2 ELISA Kit (Sandwich ELISA) - LS-F4401 from LifeSpan Bioscience Category ELISA Kit Prices $690.00 Sizes 1 plate Sensitivity 33 pg/ml Range 78.13-5000 pg/ml

Human DKK2 ELISA Kit (Sandwich ELISA) - LS-F11302 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 0.312 Range 78.13-5000 pg/ml

Human DKK2 ELISA Kit - abx151323 from Abbexa Category ELISA Kit Sensitivity 3.4 pg/ml Range 7.813 pg/ml - 500 pg/ml

Dickkopf Related Protein 2 (DKK2), Human, ELISA Kit - SEB033Hu from ARP American Research Products Category ELISA Kit Prices $685.00 Sizes 96 t Sensitivity 3.4pg/mL Range 7.8-500pg/mL

Dickkopf-related protein 2 (DKK2), Human, ELISA Kit - CSB-EL006921HU from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Dickkopf-related protein 2, DKK2, Human, ELISA Kit - E9039h from ARP American Research Products Category ELISA Kit Prices $660.00 Sizes 96 t Range 0.312-20 ng/mL

Dickkopf Related Protein 2, DKK2, Human, ELISA Kit - E-EL-H0862 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 0.094 Range 0.156-10ng/mL

Dickkopf Related Protein 2, DKK2, Mouse, ELISA Kit - E-EL-M0414 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t Sensitivity 4.688 Range 7.813-500pg/mL

Dickkopf Related Protein 2, DKK2, Rat, ELISA Kit - E-EL-R0333 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t Sensitivity 0.094 Range 0.156-10U/mL

Dickkopf Related Protein 2, DKK2, Rabbit, ELISA Kit - E-EL-RB1005 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Dickkopf Related Protein 2, DKK2, Chicken, ELISA Kit - E-EL-Ch0850 from ARP American Research Products Category ELISA Kit Prices $504.00 Sizes 96 t

Dickkopf Related Protein 2, DKK2, Porcine, ELISA Kit - E-EL-P1430 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Dickkopf Related Protein 2, DKK2, Guinea Pig, ELISA Kit - E-EL-GP0463 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t

Dickkopf Related Protein 2, DKK2, Monkey, ELISA Kit - E-EL-MK0321 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Human DKK2 ELISA Kit - HD0170 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Anserine DKK2 ELISA Kit - AD0170 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Human DKK2(Dickkopf Related Protein 2) ELISA Kit - E-EL-H0862 from Elabscience Category ELISA Kit Sensitivity 0.10 ng/mL Range 0.16—10 ng/mL

Human DKK2 (Dickkopf Related Protein 2) CLIA Kit - E-CL-H0598 from Elabscience Category CLIA Kit Sensitivity 18.75 pg/mL Range Average Recovery (%)

dickkopf homolog 2 (Xenopus laevis) , ELISA Kit - MBS934064 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of human DKK2 is typically less than 0.078 ng/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations. Range 0.312 ng/ml-20 ng/ml.

Dickkopf Related Protein 2, ELISA Kit - MBS040450 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Dickkopf Related Protein 2, ELISA Kit - MBS065282 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Dickkopf Related Protein 2, ELISA Kit - MBS085021 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Dickkopf Related Protein 2, ELISA Kit - MBS721698 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Dickkopf Related Protein 2, ELISA Kit - MBS049455 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Dickkopf Related Protein 2, ELISA Kit - MBS007729 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

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