TIGIT

Gene Symbol	TIGIT
Entrez Gene	201633
Alt Symbol	VSIG9, VSTM3, WUCAM
Species	Human
Gene Type	protein-coding
Description	T cell immunoreceptor with Ig and ITIM domains
Other Description	T-cell immunoreceptor with Ig and ITIM domains|V-set and immunoglobulin domain containing 9|V-set and immunoglobulin domain-containing protein 9|V-set and transmembrane domain containing 3|V-set and transmembrane domain-containing protein 3|Washington University cell adhesion molecule
Swissprots	Q8N877 Q495A1 Q6MZS2 Q495A3 Q5JPD8
Accessions	EAW79602 Q495A1 AK097192 BAC04973 AL833175 CAI46183 BC101288 AAI01289 BC101289 AAI01290 BC101290 AAI01291 BC101291 AAI01292 BX640915 CAE45956 EU675310 ACD74757 XM_011512538 XP_011510840 XM_011512539 XP_011510841 NM_173799 NP_776160
Function	Binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T-cell activation by promoting the generation of mature immunoregulatory dendritic cells. {ECO:0000269|PubMed:19011627}.
Subcellular Location	Cell membrane {ECO:0000269|PubMed:19011627}; Single-pass type I membrane protein {ECO:0000269|PubMed:19011627}.
Tissue Specificity	Expressed at low levels on peripheral memory and regulatory CD4+ T-cells and NK cells and is up-regulated following activation of these cells (at protein level). {ECO:0000269|PubMed:19011627}.
Top Pathways	Cell adhesion molecules (CAMs)

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

T cell immunoreceptor with Ig and ITIM domains (TIGIT), Human, ELISA Kit - CSB-EL023545HU from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

T cell immunoreceptor with Ig and ITIM domains, ELISA Kit - MBS925929 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.039 ng/ml. Range 0.156 ng/ml-10 ng/ml.

T-Cell Immunoreceptor With Ig And ITIM Domains Protein (TIGIT), ELISA Kit - MBS2024744 from MyBioSource Category ELISA Kit Prices $410.00, $610.00, $830.00, $3,420.00, $6,200.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity Typically less than 0.137ng/mL. Range 0.313-20ng/mL

ELISA Kit for T-Cell Immunoreceptor With Ig And ITIM Domains Protein (TIGIT) - SEN056Hu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.137ng/mL. Range 0.313-20ng/mL The standard curve concentrations used for the ELISA’s were 20ng/mL, 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL

Human T cell immunoreceptor with Ig and ITIM domains(TIGIT) ELISA kit - CSB-EL023545HU from Cusabio Category ELISA Kit Sensitivity 0.039 ng/ml Range 0.156 ng/ml-10 ng/ml

ELISA Kit for T-Cell Immunoreceptor With Ig And ITIM Domains Protein (TIGIT) - SEN056Hu from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.137ng/mL. Range 0.313-20ng/mL The standard curve concentrations used for the ELISA's were 20ng/mL, 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL

Human T-Cell Immunoreceptor With Ig And ITIM Domains Protein (TIGIT) ELISA Kit - EKU08370 from Biomatik Category ELISA Kit Prices $809.00, $3,557.00, $6,468.00 Sizes 96 t, 5x96t, 10x96t Sensitivity 0.133 ng/mL Range 0.312-20 ng/mL

Human T-Cell Immunoreceptor With Ig And ITIM Domains Protein ELISA Kit - abx258129 from Abbexa Category ELISA Kit Range 0.313 ng/ml - 20 ng/ml

Human TIGIT ELISA Kit (Sandwich ELISA) - LS-F25608 from LifeSpan Bioscience Category ELISA Kit Prices $850.00 Sizes 1 plate Sensitivity 0.118 ng/ml Range 0.313-20 ng/ml

Human T cell immunoreceptor with Ig and ITIM domains(TIGIT) ELISA Kit - EKC35707 from Biomatik Category ELISA Kit Prices $705.00, $2,820.00, $5,287.50 Sizes 96 t, 5x96t, 10x96t Sensitivity 0.039 ng/ml Range 0.156 ng/ml-10 ng/ml

Human TIGIT ELISA - ELH-TIGIT-1 from RayBiotech Category ELISA Kit Prices $615.00, $1,107.00, $2,460.00 Sizes 1 plate kit, 2 plate kit, 5 plate kit

Custom Human TIGIT ELISA Kit - orb384879 from Biorbyt Category ELISA Kit Prices $1,411.00, $2,448.00, $5,321.00 Sizes 96 assays, 192 assays, 480 assays

Human TIGIT ELISA Kit - E037270 from Biobool Category ELISA Kit

TIGIT ELISA Kit (Human) (OKCD01082) - OKCD01082 from Aviva Systems Biology Category ELISA Kit Prices $585.00 Sizes 96 wells Sensitivity < 0.133 ng/mL Range 0.312-20 ng/mL

Human T cell immunoreceptor with Ig and ITIM domains (TIGIT) ELISA Kit - AE59653HU from ARP American Research Products Category ELISA Kit Prices $549.00 Sizes 96 t Sensitivity 0.133 ng/mL Range 0.312-20 ng/mL

T cell immunoreceptor with Ig and ITIM domains (TIGIT), ELISA Kit - MBS2610495 from MyBioSource Category ELISA Kit Prices $300.00, $475.00, $1,825.00, $3,425.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Human T cell immunoreceptor with Ig and ITIM domains (TIGIT) ELISA kit - EKC41976 from Biomatik Category ELISA Kit Prices $709.00 Sizes 96 tests Sensitivity 0.039 ng/mL Range 0.156 ng/mL-10 ng/mL

TIGIT (Human) ELISA Kit - E4549 from Biovision Category ELISA Kit Prices $750.00 Sizes 100 assays

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