ARC

Gene Symbol	ARC
Entrez Gene	23237
Alt Symbol	Arg3.1
Species	Human
Gene Type	protein-coding
Description	activity-regulated cytoskeleton-associated protein
Other Description	ARC/ARG3.1|activity-regulated gene 3.1 protein homolog
Swissprots	Q9UJW6 Q9Y469 Q7LC44
Accessions	AAG33705 CBX47608 EAW82320 EAW82321 Q7LC44 AF193421 AAF07185 AI096899 BC012321 AAH12321 BC075802 AAH75802 BI752734 D87468 BAA19667 DQ893666 ABM84592 DQ895780 ABM86706 NM_015193 NP_056008
Function	Required for consolidation of synaptic plasticity as well as formation of long-term memory. Regulates endocytosis of AMPA receptors in response to synaptic activity. Required for homeostatic synaptic scaling of AMPA receptors (By similarity). Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the stress fiber dynamics and cell migration. {ECO:0000250, ECO:0000269|PubMed:21834987}.
Subcellular Location	Cytoplasm, cytoskeleton {ECO:0000250}. Endosome {ECO:0000250|UniProtKB:Q63053, ECO:0000250|UniProtKB:Q9WV31}. Cytoplasmic vesicle, secretory vesicle, acrosome {ECO:0000250|UniProtKB:Q63053, ECO:0000250|UniProtKB:Q9WV31}. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density {ECO:0000250}. Cell projection, dendrite {ECO:0000250}. Cell projection, dendritic spine {ECO:0000250}. Cell junction, synapse {ECO:0000250}. Note=Associated with the cell cortex of neuronal soma and dendrites. Enriched in postsynaptic density of dendritic spines. Associated with the sperm tail (By similarity). Enriched on the plasma membrane. {ECO:0000250, ECO:0000269|PubMed:21834987}.
Top Pathways	Amphetamine addiction

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Mouse ARC / Arg3.1 ELISA Kit (Sandwich ELISA) - LS-F7194 from LifeSpan Bioscience Category ELISA Kit Prices $740.00 Sizes 1 plate Sensitivity 0.065 ng/ml Range 0.156-10 ng/ml

Rat ARC / Arg3.1 ELISA Kit (Sandwich ELISA) - LS-F9610 from LifeSpan Bioscience Category ELISA Kit Prices $780.00 Sizes 1 plate Sensitivity 0.051 ng/ml Range 0.156-10 ng/ml

Human ARC / Arg3.1 ELISA Kit (Sandwich ELISA) - LS-F10880 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 0.156 ng/ml Range 0.156-10 ng/ml

Activity-regulated cytoskeleton-associated protein (ARC), Human, ELISA Kit - CSB-EL001981HU from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Activity regulated cytoskeleton associated protein (ARC), ELISA Kit - MBS7241755 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.1 ng/mL.

Activity Regulated Cytoskeleton Associated Protein (ARC), ELISA Kit - MBS2022192 from MyBioSource Category ELISA Kit Prices $405.00, $605.00, $820.00, $3,375.00, $6,125.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity Typically less than 0.051ng/mL. Range 0.156-10ng/mL

Activity Regulated Cytoskeleton Associated Protein (ARC), ELISA Kit - MBS2019759 from MyBioSource Category ELISA Kit Prices $385.00, $575.00, $785.00, $3,210.00, $5,825.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity Typically less than 0.059ng/mL. Range 0.156-10ng/mL

activity-regulated cytoskeleton-associated protein, ELISA Kit - MBS915576 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 6.25 pg/ml. Range 25 pg/ml-1600 pg/ml.

Activity-regulated cytoskeleton-associated protein, ELISA Kit - MBS282867 from MyBioSource Category ELISA Kit Prices $425.00, $720.00, $3,160.00, $6,055.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Activity-regulated cytoskeleton-associated protein (ARC), ELISA Kit - MBS7207171 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Activity-regulated cytoskeleton-associated protein (ARC), ELISA Kit - MBS7205647 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Activity-regulated cytoskeleton-associated protein (ARC), ELISA Kit - MBS7202112 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Activity-regulated cytoskeleton-associated protein (ARC), ELISA Kit - MBS7221329 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Activity-regulated cytoskeleton-associated protein (ARC), ELISA Kit - MBS7226724 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Activity-regulated cytoskeleton-associated protein (ARC), ELISA Kit - MBS7227252 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Activity-regulated cytoskeleton-associated protein (ARC), ELISA Kit - MBS7247531 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Activity-regulated cytoskeleton-associated protein (ARC), ELISA Kit - MBS7218882 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Activity-regulated cytoskeleton-associated protein (ARC), ELISA Kit - MBS7242184 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Activity-regulated cytoskeleton-associated protein (ARC), ELISA Kit - MBS7223261 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Activity-regulated cytoskeleton-associated protein (ARC), ELISA Kit - MBS7219950 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.1 ng/mL.

ELISA Kit for Activity Regulated Cytoskeleton Associated Protein (ARC) - SEJ620Mu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.059ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA’s were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

ELISA Kit for Activity Regulated Cytoskeleton Associated Protein (ARC) - SEJ620Ra from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.051ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA’s were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

Human Activity-regulated cytoskeleton-associated protein(ARC) ELISA kit - CSB-EL001981HU from Cusabio Category ELISA Kit Sensitivity 6.25 pg/ml Range 25 pg/ml-1600 pg/ml

Mouse ARC / Arg3.1 ELISA Kit (Custom ELISA) - LS-F20128 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity To be determined Range 0.156-10 ng/ml

Rat ARC / Arg3.1 ELISA Kit (Custom ELISA) - LS-F20130 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity To be determined Range 0.156-10 ng/ml

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